CometAssay Single Cell Gel Electrophoresis Assay 4250-050-K from R&D Systems, a Bio-Techne Brand

Product Specs
ItemCometAssay Single Cell Gel Electrophoresis Assay
CompanyR&D Systems, a Bio-Techne Brand
Price Pricing Info Supplier Page View Company Product Page
Catalog Number4250-050-K
Quantity50 Tests
Brand/TrademarkR&D Systems, a Bio-Techne Brand
StorageThe product requires storage at both 2 - 8 °C and room temperature. Consult the product insert for specific storage temperatures. Do not use past expiration date

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) SOD1 is a synthetic lethal target in PPM1D-mutant leukemia cellsbioRxiv : the preprint server for biologyJanuary 17, 2024Zhang L, Hsu JI, Braekeleer ED, Chen CW, Patel TD, Martell AG, Guzman AG, Wohlan K, Waldvogel SM, Urya H, et al.

(2) Targeting of RRM2 suppresses DNA damage response and activates apoptosis in atypical teratoid rhabdoid tumorJ Exp Clin Cancer ResDecember 20, 2023Le Hien Giang, Kuo-Sheng Wu, Wei-Chung Lee, Shing-Shung Chu, Anh Duy Do, Chun A. Changou, Huy Minh Tran, Tsung-Han Hsieh, Hsin-Hung Chen, Chia-Ling Hsieh, et al.according to the manufacturer’s instructions of Comet Assay kit (R&D System, Bio-Techne, MN, USA, cat# 4250-050-K). The individual cells or comets were viewed and photographed using a fluorescent microscope (Zeiss)

(3) The synthetic food dye, Red 40, causes DNA damage, causes colonic inflammation, and impacts the microbiome in miceToxicology reportsDecember 1, 2023Zhang Q, Chumanevich AA, Nguyen I, Chumanevich AA, Sartawi N, Hogan J, Khazan M, Harris Q, Massey B, Chatzistamou I, et al.

(4) Copy Number Variation That Influences the Ionizing Radiation Sensitivity of Oral Squamous Cell CarcinomaCellsOctober 10, 2023Tadahide Izumi, Piotr Rychahou, Li Chen, Molly H. Smith, Joseph Valentinoreagents, including low melting agarose, lysis buffer, and slides, were included in the comet assay kit (4250-050-K) purchased from R&D systems (Minneapolis, MN, USA). FaDu cells and their shRNA knockdown (kd) derivatives

(5) DePARylation is critical for S phase progression and cell survivalbioRxiv : the preprint server for biologyOctober 6, 2023Nie L, Wang C, Huang M, Liu X, Feng X, Tang M, Li S, Hang Q, Teng H, Shen X, et al.

(6) Downregulation of Krüppel-like factor 14 accelerated cellular senescence and agingAging cellOctober 1, 2023Hou Y, Song Q, Wang Y, Liu J, Cui Y, Zhang X, Zhang J, Fu J, Cao M, Zhang C, et al.

(7) Bortezomib Is Effective in the Treatment of T Lymphoblastic Leukaemia by Inducing DNA Damage, WEE1 Downregulation, and Mitotic CatastropheInternational Journal of Molecular SciencesSeptember 27, 2023Rahman Ud Din, Anan Jiao, Yinxia Qiu, Aarmann Anil Mohinani Mohan, Kei-Ching Yuen, Hoi-Tung Wong, Timothy Ming-Hun Wan, Phoebe On-Yi Wong, Chun-Fung SinMeasuring DNA Damage CometAssay® Reagent Kit for a Single Cell Gel Electrophoresis Assay Catalog # 4250-050-K was purchased from R&D systems, and the reagents were made according to the manufacturer’s instructions.

(8) A Side-by-Side Comparison of Wildtype and Variant Melanocortin 1 Receptor Signaling with Emphasis on Protection against Oxidative Damage to DNAInternational journal of molecular sciencesSeptember 21, 2023Cerdido S, Sánchez-Beltrán J, Lambertos A, Abrisqueta M, Padilla L, Herraiz C, Olivares C, Jiménez-Cervantes C, García-Borrón JC.

(9) The fructose-bisphosphate, Aldolase A (ALDOA), facilitates DNA-PKcs and ATM kinase activity to regulate DNA double-strand break repairScientific reportsSeptember 13, 2023Sobanski T, Suraweera A, Burgess JT, Richard I, Cheong CM, Dave K, Rose M, Adams MN, O''Byrne KJ, Richard DJ, et al.

(10) Frailty, sex, and poverty are associated with DNA damage and repair in frail, middle-aged urban adultsDNA repairSeptember 1, 2023Smith JT, Noren Hooten N, Mode NA, Zonderman AB, Ezike N, Kaushal S, Evans MK.

(11) The microbial genotoxin colibactin exacerbates mismatch repair mutations in colorectal tumorsNeoplasiaSeptember 1, 2023Michael W. Dougherty, Rafael Valdés-Mas, Kevin M. Wernke, Raad Z. Gharaibeh, Ye Yang, Jason O. Brant, Alberto Riva, Marcus Muehlbauer, Eran Elinav, Jens Puschhof, et al.strand breaks were analyzed by alkaline comet assay using the CometAssay Single Gel Electrophoresis Kit (4250-050-K, R&D Systems) following the manufacturer's protocol as previously described [32]. DNA was stained with

(12) Circadian control of cisplatin-DNA adduct repair and apoptosis in culture cellsThe international journal of biochemistry & cell biologySeptember 1, 2023Jeon J, Lee S, Park JM, Lee TH, Kang TH.

(13) The DDUP protein encoded by the DNA damage-induced CTBP1-DT lncRNA confers cisplatin resistance in ovarian cancerCell death & diseaseAugust 26, 2023Ren L, Qing X, Wei J, Mo H, Liu Y, Zhi Y, Lu W, Zheng M, Zhang W, Chen Y, et al.

(14) Identification of a de novo mutation in TLK1 associated with a neurodevelopmental disorder and immunodeficiencymedRxiv : the preprint server for health sciencesAugust 24, 2023Villamor-Payà M, Sanchiz-Calvo M, Smak J, Pais L, Sud M, Shankavaram U, Lovgren AK, Austin-Tse C, Ganesh VS, Gay M, et al.

(15) Loss of SYNCRIP unleashes APOBEC-driven mutagenesis, tumor heterogeneity, and AR-targeted therapy resistance in prostate cancerCancer cellAugust 14, 2023Li X, Wang Y, Deng S, Zhu G, Wang C, Johnson NA, Zhang Z, Tirado CR, Xu Y, Metang LA, et al.One Shot™ Stbl3™ Chemically Competent E. coli,Thermo Fisher Scientific,C737303 CometAssay Single Cell Gel Electrophoresis Assay,R&D Systems,4250-050-K ,, Deposited data,Deposited data,Deposited data ,, RNA-seq,This paper,[GEO]: [GSE202321] Exome-seq,This

(16) PC4-mediated Ku complex PARylation facilitates NHEJ-dependent DNA damage repairThe Journal of biological chemistryAugust 1, 2023Pan Q, Luo P, Shi C.manufacturer’s instructions of the single-cell gel electrophoresis assay kit made by R&D systems (Catalog#4250-050-K). In brief, cells were treated with 2 Gy of X-ray irradiation (Rad source) and harvested either just

(17) RAD54L regulates replication fork progression and nascent strand degradation in BRCA1/2-deficient cellsbioRxiv : the preprint server for biologyJuly 26, 2023Uhrig ME, Sharma N, Maxwell P, Selemenakis P, Wiese C.

(18) BRD4 directs mitotic cell division by inhibiting DNA damagebioRxiv : the preprint server for biologyJuly 25, 2023Wu T, Hou H, Dey A, Bachu M, Chen X, Wisniewski J, Kudoh F, Chen C, Chauhan S, Xiao H, et al.

(19) Replisome dysfunction upon inducible TIMELESS degradation synergizes with ATR inhibition to trigger replication catastropheNucleic acids researchJuly 7, 2023Patel JA, Zezelic C, Rageul J, Saldanha J, Khan A, Kim H.

(20) A novel multifunctional radioprotective strategy using P7C3 as a countermeasure against ionizing radiation-induced bone lossBone researchJune 29, 2023Wei F, Tuong ZK, Omer M, Ngo C, Asiatico J, Kinzel M, Pugazhendhi AS, Khaled AR, Ghosh R, Coathup M.area (µm2) was quantified using ZEN 3.1 software (Zeiss, USA). DNA damage in hBMSCs A Comet Assay® (4250-050-K, R&D Systems, USA) was used to assess IR-induced DNA damage to hBMSCs. Briefly, the cells were detached

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CometAssay Single Cell Gel Electrophoresis Assay from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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CometAssay Single Cell Gel Electrophoresis Assay from R&D Systems, a Bio-Techne Brand

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