Description
Product Characteristics:
Stimulatory or required for the translocation of secretory proteins across the ER membrane.
Subcellular location: Cytoplasm
Synonyms: TRAM, PNAS8, TRAMP, Translocating chain-associated membrane protein 1, TRAM1
Target Information: This gene encodes a multi-pass membrane protein that is part of the mammalian endoplasmic reticulum. The encoded protein influences glycosylation and facilitates the translocation of secretory proteins across the endoplasmic reticulum membrane by regulating which domains of the nascent polypeptide chain are visible to the cytosol during a translocational pause. [provided by RefSeq, Oct 2009]