InVivoMab anti-mouse LAG-3 BE0174-R025mg from Bio X Cell

Product Specs
ItemInVivoMab anti-mouse LAG-3
CompanyBio X Cell
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberBE0174-R025mg
Quantity25 mg
Applicationsin vivo LAG-3 neutralization, in vitro LAG-3 neutralization, Flow cytometry, Western blot
ConcentrationLot specific,typically between 4-11 mg/ml
Conjugate/TagUnconjugated
ReactivityMouse
TargetLAG-3
IsotypeIgG1, κ
CloneC9B7W
Hostrat
NCBI Full Gene Namelymphocyte-activation gene 3
NCBI Gene AliasesCD223, LAG-3, Ly66
ClonalityMonoclonal
ImmunogenMouse CD223-Ig fusion protein
Antibody TypePrimary Antibody
Purity>95%, Determined by SDS-PAGE
FormatPBS, pH 7.0, Contains no stabilizers or preservatives
Research AreaCancer Biology, Immune Checkpoint Protein, Immunology

Other available quantities: Available in 1, 5, 10, 25, 50, 100 mg and bulk sizes. Academic discount available.

Endotoxin: <2EU/mg (<0.002EU/µg), Determined by LAL gel clotting assay

39 Labombard Rd

Lebanon, NH 03766

United States

Phone: 1-866-787-3444

Email: customerservice@bxcell.com

(1) LAG3⁺ Regulatory T Cells Restrain Interleukin-23-Producing CX3CR1⁺ Gut-Resident Macrophages during Group 3 Innate Lymphoid Cell-Driven ColitisImmunityAugust 21, 2018Bauché D, Joyce-Shaikh B, Jain R, Grein J, Ku KS, Blumenschein WM, Ganal-Vonarburg SC, Wilson DC, McClanahan TK, Malefyt RW, et al.

(2) Roles of lymphatic endothelial cells expressing peripheral tissue antigens in CD4 T-cell tolerance inductionNature communicationsApril 10, 2015Rouhani SJ, Eccles JD, Riccardi P, Peske JD, Tewalt EF, Cohen JN, Liblau R, Mäkinen T, Engelhard VH.

(4) Programmed death-1 impairs secondary effector lung CD8⁺ T cells during respiratory virus reinfectionJournal of immunology (Baltimore, Md. : 1950)November 15, 2014Erickson JJ, Rogers MC, Hastings AK, Tollefson SJ, Williams JV.

(5) Immunotherapy-induced CD8+ T cells instigate immune suppression in the tumorMolecular therapy : the journal of the American Society of Gene TherapyJanuary 1, 2014McGray AJ, Hallett R, Bernard D, Swift SL, Zhu Z, Teoderascu F, Vanseggelen H, Hassell JA, Hurwitz AA, Wan Y, et al.

(6) Lymphocyte Activation Gene 3 (LAG-3) modulates the ability of CD4 T-cells to be suppressed in vivoPloS oneJanuary 1, 2014Durham NM, Nirschl CJ, Jackson CM, Elias J, Kochel CM, Anders RA, Drake CG.

(7) Restoring immune function of tumor-specific CD4+ T cells during recurrence of melanomaJournal of immunology (Baltimore, Md. : 1950)May 1, 2013Goding SR, Wilson KA, Xie Y, Harris KM, Baxi A, Akpinarli A, Fulton A, Tamada K, Strome SE, Antony PA.

InVivoMab anti-mouse LAG-3