InVivoMab anti-mouse CD28 BE0015-1-R050mg from Bio X Cell

Product Specs
ItemInVivoMab anti-mouse CD28
CompanyBio X Cell
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberBE0015-1-R050mg
Quantity50 mg
Applicationsin vitro T cell stimulation/activation, in vivo CD28 blockade
ConcentrationLot specific,typically between 4-11 mg/ml
Conjugate/TagUnconjugated
ReactivityMouse
TargetCD28
IsotypeIgG2
Clone37.51
HostSyrian hamster
NCBI Full Gene NameCD28 antigen
ClonalityMonoclonal
ImmunogenC57BL/6 mouse T cell lymphoma EL-4 cells
Antibody TypePrimary Antibody
Purity>95%, Determined by SDS-PAGE
FormatPBS, pH 6.0, 0.01% Tween, Contains no stabilizers or preservatives
Research AreaCancer Biology, Immune Checkpoint Protein, Immunology

Specifications/Features

Other available quantities: Available in 1, 5, 10, 25, 50, 100 mg and bulk sizes. Academic discount available.

Endotoxin: <2EU/mg (<0.002EU/µg), Determined by LAL gel clotting assay

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Bio X Cell

39 Labombard Rd

Lebanon, NH 03766

United States

Phone: 1-866-787-3444

Email: customerservice@bxcell.com

Company Profile

Website: bioxcell.com

(1) Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor ImmunityCellDecember 23, 2020Ringel AE, Drijvers JM, Baker GJ, Catozzi A, García-Cañaveras JC, Gassaway BM, Miller BC, Juneja VR, Nguyen TH, Joshi S, et al.#145-2C11",BioXCell,Cat#BE0001-1; RRID: AB_1107634 "InVivoMAb anti-mouse CD28, Clone #37.51",BioXCell,Cat#BE0015-1-A050MG; RRID: AB_1107624 "InVivoMAb rat IgG2b isotype control, anti-keyhole limpet hemocyanin",BioXCell,Clone:

(2) Sensing of ATP via the Purinergic Receptor P2RX7 Promotes CD8⁺ Trm Cell Generation by Enhancing Their Sensitivity to the Cytokine TGF-βImmunityJuly 14, 2020Borges da Silva H, Peng C, Wang H, Wanhainen KM, Ma C, Lopez S, Khoruts A, Zhang N, Jameson SC.145–2C11, Cat no. BE0001–1; RRID:AB_1107634" InVivoMAb anti-mouse CD28,BioXCell,"Clone 37.51, Cat no. BE0015–1-A050mg; RRID:AB_1107624" Anti-mouse pSMAD2/3 (pS465/pS467) PE,BD Biosciences,"Clone 072–670, Cat no. 562586;

(3) TLR1/2 Specific Small-Molecule Agonist Suppresses Leukemia Cancer Cell Growth by Stimulating Cytotoxic T LymphocytesAdvanced science (Weinheim, Baden-Wurttemberg, Germany)May 17, 2019Cen X, Zhu G, Yang J, Yang J, Guo J, Jin J, Nandakumar KS, Yang W, Yin H, Liu S, et al.stimulated with 5 µg mL−1 plate‐bound anti‐CD3 (BE0001‐1‐A005MG, BioXcell) and anti‐CD28 antibodies (BE0015‐1‐A005MG, BioXcell) for 48 or 72 h and incubated in 1 mL proliferation culture medium (1640 + 10% FBS+βME+10

(4) NF-κB inducing kinase (NIK) is an essential post-transcriptional regulator of T-cell activation affecting F-actin dynamics and TCR signalingJournal of autoimmunityNovember 1, 2018Lacher SM, Thurm C, Distler U, Mohebiany AN, Israel N, Kitic M, Ebering A, Tang Y, Klein M, Wabnitz GH, et al.

(5) Retinoic Acid Signaling in Thymic Epithelial Cells Regulates ThymopoiesisJournal of immunology (Baltimore, Md. : 1950)July 15, 2018Wendland K, Niss K, Kotarsky K, Wu NYH, White AJ, Jendholm J, Rivollier A, Izarzugaza JMG, Brunak S, Holländer GA, et al.

(6) Mitochondrial Biogenesis and Proteome Remodeling Promote One-Carbon Metabolism for T Cell ActivationCell metabolismJuly 12, 2016Ron-Harel N, Santos D, Ghergurovich JM, Sage PT, Reddy A, Lovitch SB, Dephoure N, Satterstrom FK, Sheffer M, Spinelli JB, et al.

(7) Regulation of bifurcating B cell trajectories by mutual antagonism between transcription factors IRF4 and IRF8Nature immunologyDecember 1, 2015Xu H, Chaudhri VK, Wu Z, Biliouris K, Dienger-Stambaugh K, Rochman Y, Singh H.

(8) LEF-1 and TCF-1 orchestrate T(FH) differentiation by regulating differentiation circuits upstream of the transcriptional repressor Bcl6Nature immunologySeptember 1, 2015Choi YS, Gullicksrud JA, Xing S, Zeng Z, Shan Q, Li F, Love PE, Peng W, Xue HH, Crotty S.

(9) Roles of lymphatic endothelial cells expressing peripheral tissue antigens in CD4 T-cell tolerance inductionNature communicationsApril 10, 2015Rouhani SJ, Eccles JD, Riccardi P, Peske JD, Tewalt EF, Cohen JN, Liblau R, Mäkinen T, Engelhard VH.

(10) A critical role for transcription factor Smad4 in T cell function that is independent of transforming growth factor β receptor signalingImmunityJanuary 20, 2015Gu AD, Zhang S, Wang Y, Xiong H, Curtis TA, Wan YY.

(11) The oncoprotein and transcriptional regulator Bcl-3 governs plasticity and pathogenicity of autoimmune T cellsImmunityOctober 16, 2014Tang W, Wang H, Claudio E, Tassi I, Ha HL, Saret S, Siebenlist U.

(12) The E3 ubiquitin ligase Itch is required for the differentiation of follicular helper T cellsNature immunologyJuly 1, 2014Xiao N, Eto D, Elly C, Peng G, Crotty S, Liu YC.

(13) Differential kinetics of antigen dependency of CD4+ and CD8+ T cellsJournal of immunology (Baltimore, Md. : 1950)April 15, 2014Rabenstein H, Behrendt AC, Ellwart JW, Naumann R, Horsch M, Beckers J, Obst R.

(14) Bcl6 expressing follicular helper CD4 T cells are fate committed early and have the capacity to form memoryJournal of immunology (Baltimore, Md. : 1950)April 15, 2013Choi YS, Yang JA, Yusuf I, Johnston RJ, Greenbaum J, Peters B, Crotty S.

(15) Multiple layers of CD80/86-dependent costimulatory activity regulate primary, memory, and secondary lymphocytic choriomeningitis virus-specific T cell immunityJournal of virologyFebruary 1, 2012Eberlein J, Davenport B, Nguyen TT, Victorino F, Sparwasser T, Homann D.

(16) Regulation of IL-9 expression by IL-25 signalingNature immunologyMarch 1, 2010Angkasekwinai P, Chang SH, Thapa M, Watarai H, Dong C.

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InVivoMab anti-mouse CD28

InVivoMab anti-mouse CD28 from Bio X Cell

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Bio X Cell

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InVivoMab anti-mouse CD28 from Bio X Cell

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