Description
Product Characteristics:
Replicates viral genomic DNA. The replication complex is composed of six viral proteins: the DNA polymerase, processivity factor, primase, primase-associated factor, helicase, and ssDNA-binding protein. Additionally, the polymerase contains an intrinsic ribonuclease H (RNase H) activity that specifically degrades RNA/DNA heteroduplexes or duplex DNA substrates in the 5' to 3' direction. Therefore, it can catalyze the excision of the RNA primers that initiate the synthesis of Okazaki fragments at a replication fork during viral DNA replication.
Subcellular location: Nucleus
Synonyms: DPOL_HHV11, DNA polymerase catalytic subunit, UL30, HHV1gp046.
Target Information: Please see product details or send an inquiry to antibodies-online for additional target information