InVivoPlus anti-mouse TIM-3 (CD366) BP0115-R025mg from Bio X Cell

Product Specs
ItemInVivoPlus anti-mouse TIM-3 (CD366)
CompanyBio X Cell
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberBP0115-R025mg
Quantity25 mg
Applicationsin vivo TIM-3 neutralization, in vitro TIM-3 blocking, Flow cytometry
ConcentrationLot specific,typically between 4-11 mg/ml
Conjugate/TagUnconjugated
ReactivityMouse
TargetTIM-3
IsotypeIgG2a, κ
CloneRMT3-23
Hostrat
NCBI Full Gene Namehepatitis A virus cellular receptor 2
NCBI Gene AliasesTIM-3, Tim3, Timd3
ClonalityMonoclonal
ImmunogenRecombinant mouse TIM-3
Antibody TypePrimary Antibody
Purity>95%, Determined by SDS-PAGE
FormatPBS, pH 7.0, Contains no stabilizers or preservatives
Research AreaApoptosis, Cancer Biology, Immune Checkpoint Protein, Immunology

Specifications/Features

Other available quantities: Available in 1, 5, 10, 25, 50, 100 mg and bulk sizes. Academic discount available.

Endotoxin: <1EU/mg (<0.001EU/µg), Determined by LAL gel clotting assay

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Bio X Cell

39 Labombard Rd

Lebanon, NH 03766

United States

Phone: 1-866-787-3444

Email: customerservice@bxcell.com

Company Profile

Website: bioxcell.com

(1) Leveraging TCR Affinity in Adoptive Immunotherapy against Shared Tumor/Self-AntigensCancer Immunology ResearchJanuary 1, 2019Aaron M. Miller, Milad Bahmanof, Dietmar Zehn, Ezra E. W. Cohen, Stephen P. Schoenberger#BP0033-2), InVivoPlus anti-mouse LAG-3 (C9B7W; Cat. #BP0174) and InVivoPlus anti-mouse TIM-3 (RMT3-23; Cat. #BP0115). A total of 250 µg of each antibody was transferred intravenously in 200 µL of PBS into recipient mice. Statistical

(2) Blockade of TIM3 relieves immunosuppression through reducing regulatory T cells in head and neck cancerJournal of experimental & clinical cancer research : CRMarch 5, 2018Liu JF, Wu L, Yang LL, Deng WW, Mao L, Wu H, Zhang WF, Sun ZJ.

(3) TIGIT predominantly regulates the immune response via regulatory T cellsThe Journal of clinical investigationNovember 2, 2015Kurtulus S, Sakuishi K, Ngiow SF, Joller N, Tan DJ, Teng MW, Smyth MJ, Kuchroo VK, Anderson AC.

(4) A Threshold Level of Intratumor CD8+ T-cell PD1 Expression Dictates Therapeutic Response to Anti-PD1Cancer researchSeptember 15, 2015Ngiow SF, Young A, Jacquelot N, Yamazaki T, Enot D, Zitvogel L, Smyth MJ.

(5) Effect of TIM-3 Blockade on the Immunophenotype and Cytokine Profile of Murine Uterine NK CellsPloS oneJanuary 1, 2015Tripathi S, Chabtini L, Dakle PJ, Smith B, Akiba H, Yagita H, Guleria I.

(6) Programmed death-1 impairs secondary effector lung CD8⁺ T cells during respiratory virus reinfectionJournal of immunology (Baltimore, Md. : 1950)November 15, 2014Erickson JJ, Rogers MC, Hastings AK, Tollefson SJ, Williams JV.

(7) Antimetastatic effects of blocking PD-1 and the adenosine A2A receptorCancer researchJuly 15, 2014Mittal D, Young A, Stannard K, Yong M, Teng MW, Allard B, Stagg J, Smyth MJ.

(8) Liver-primed CD8+ T cells suppress antiviral adaptive immunity through galectin-9-independent T-cell immunoglobulin and mucin 3 engagement of high-mobility group box 1 in miceHepatology (Baltimore, Md.)April 1, 2014Dolina JS, Braciale TJ, Hahn YS.

(9) Immunotherapy-induced CD8+ T cells instigate immune suppression in the tumorMolecular therapy : the journal of the American Society of Gene TherapyJanuary 1, 2014McGray AJ, Hallett R, Bernard D, Swift SL, Zhu Z, Teoderascu F, Vanseggelen H, Hassell JA, Hurwitz AA, Wan Y, et al.

(10) Combining regulatory T cell depletion and inhibitory receptor blockade improves reactivation of exhausted virus-specific CD8+ T cells and efficiently reduces chronic retroviral loadsPLoS pathogensJanuary 1, 2013Dietze KK, Zelinskyy G, Liu J, Kretzmer F, Schimmer S, Dittmer U.

(11) Virus-specific CD8+ T cells upregulate programmed death-1 expression during acute friend retrovirus infection but are highly cytotoxic and control virus replicationJournal of immunology (Baltimore, Md. : 1950)October 1, 2011Zelinskyy G, Myers L, Dietze KK, Gibbert K, Roggendorf M, Liu J, Lu M, Kraft AR, Teichgräber V, Hasenkrug KJ, et al.

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InVivoPlus anti-mouse TIM-3 (CD366)

InVivoPlus anti-mouse TIM-3 (CD366)

InVivoPlus anti-mouse TIM-3 (CD366) from Bio X Cell

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Specifications/Features

Bio X Cell

Citations (11)

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InVivoPlus anti-mouse TIM-3 (CD366) from Bio X Cell

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