Activin A βA subunit Antibody MAB3381-100 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemActivin A βA subunit Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberMAB3381-100
Quantity100 ug (also 500 ug, 25 ug)
ApplicationsNeutralization, ELISA Capture (Matched Antibody Pair)
Conjugate/TagUnconjugated
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ReactivityHuman, Mouse, Rat
TargetActivin A
IsotypeIgG1
Clone69403
HostMouse
ImmunogenChinese hamster ovary cell line CHO-derived recombinant human Activin A
ClonalityMonoclonal
PurityProtein A or G purified from hybridoma culture supernatant
Brand/TrademarkR&D Systems, a Bio-Techne Brand
NCBI Full Gene Nameinhibin subunit beta A
NCBI Gene AliasesEDF, FRP
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Unconjugated

Specificity: Detects recombinant human Activin A in ELISAs. Also recognizes Activin A precursor. The amino acid sequences of mature beta A subunits from human, mouse and rat are identical. Therefore, this antibody will also detect the mature beta A subunit from mouse and rat

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) GDF8 Contributes to Liver Fibrogenesis and Concomitant Skeletal Muscle WastingBiomedicinesJuly 6, 2023Culver A, Hamang M, Wang Y, Jiang H, Yanum J, White E, Gawrieh S, Vuppalanchi RK, Chalasani NP, Dai G, et al.

(2) Orally-active, clinically-translatable senolytics restore α-Klotho in mice and humansEBioMedicineMarch 1, 2022Zhu Y, Prata LGPL, Gerdes EOW, Netto JME, Pirtskhalava T, Giorgadze N, Tripathi U, Inman CL, Johnson KO, Xue A, et al.

(3) Role of stromal activin A in human pancreatic cancer and metastasis in miceScientific reportsApril 12, 2021Mancinelli G, Torres C, Krett N, Bauer J, Castellanos K, McKinney R, Dawson D, Guzman G, Hwang R, Grimaldo S, et al.

(4) Activin A programs the differentiation of human TFH cellsNature immunologyAugust 1, 2016Locci M, Wu JE, Arumemi F, Mikulski Z, Dahlberg C, Miller AT, Crotty S.

(5) Adipose Stromal Cell Contact with Endothelial Cells Results in Loss of Complementary Vasculogenic Activity Mediated by Induction of Activin AStem CellsOctober 1, 2015Merfeld-Clauss S, Lupov IP, Lu H, March KL, Traktuev DO.

(6) Low miR-143/miR-145 Cluster Levels Induce Activin A Overexpression in Oral Squamous Cell Carcinomas, Which Contributes to Poor PrognosisPloS oneJanuary 1, 2015Bufalino A, Cervigne NK, de Oliveira CE, Fonseca FP, Rodrigues PC, Macedo CC, Sobral LM, Miguel MC, Lopes MA, Paes Leme AF, et al.

(7) CCL2 shapes macrophage polarization by GM-CSF and M-CSF: identification of CCL2/CCR2-dependent gene expression profileJournal of immunology (Baltimore, Md. : 1950)April 15, 2014Sierra-Filardi E, Nieto C, Domínguez-Soto A, Barroso R, Sánchez-Mateos P, Puig-Kroger A, López-Bravo M, Joven J, Ardavín C, Rodríguez-Fernández JL, et al.

(8) Activin A skews macrophage polarization by promoting a proinflammatory phenotype and inhibiting the acquisition of anti-inflammatory macrophage markersBloodMay 12, 2011Sierra-Filardi E, Puig-Kröger A, Blanco FJ, Nieto C, Bragado R, Palomero MI, Bernabéu C, Vega MA, Corbí AL.

(9) Activin A is an anticatabolic autocrine cytokine in articular cartilage whose production is controlled by fibroblast growth factor 2 and NF-kappaBArthritis and rheumatismNovember 1, 2007Alexander S, Watt F, Sawaji Y, Hermansson M, Saklatvala J.

(10) The neuroprotective effect of Activin A and B: implication for neurodegenerative diseasesJournal of neurochemistryNovember 1, 2007Kupershmidt L, Amit T, Bar-Am O, Youdim MB, Blumenfeld Z.

(11) Fibroblast growth factor 2 modulates transforming growth factor beta signaling in mouse embryonic fibroblasts and human ESCs (hESCs) to support hESC self-renewalStem CellsFebruary 1, 2007Greber B, Lehrach H, Adjaye J.

(12) Requirement of Smad3 for mast cell growthCellular immunologyMarch 1, 2006Funaba M, Nakaya K, Ikeda T, Murakami M, Tsuchida K, Sugino H.

(13) N-cadherin is regulated by activin A and associated with tumor aggressiveness in esophageal carcinomaClinical cancer research : an official journal of the American Association for Cancer ResearchSeptember 1, 2004Yoshinaga K, Inoue H, Utsunomiya T, Sonoda H, Masuda T, Mimori K, Tanaka Y, Mori M.

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Activin A βA subunit Antibody

Activin A βA subunit Antibody

Activin A βA subunit Antibody

Activin A βA subunit Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (13)

Reviews

Activin A βA subunit Antibody from R&D Systems, a Bio-Techne Brand

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