NKG2D/CD314 Antibody MAB1547-100 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemNKG2D/CD314 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberMAB1547-100
Quantity100 ug (also 500 ug, 25 ug)
ApplicationsWestern Blot, Flow Cytometry, Blockade of Receptor-ligand Interaction, CyTOF-ready
Conjugate/TagUnconjugated
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ReactivityMouse
TargetNKG2D/CD314
IsotypeIgG2b
Clone191004
HostRat
ImmunogenMouse myeloma cell line NS0-derived recombinant mouse NKG2D, Phe94-Val232, Accession # O54709
NCBI Full Gene Namekiller cell lectin-like receptor subfamily K, member 1
NCBI Gene AliasesNkg2d, D6H12S2489E, NKG2-D
ClonalityMonoclonal
PurityProtein A or G purified from hybridoma culture supernatant
Brand/TrademarkR&D Systems, a Bio-Techne Brand
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Unconjugated

Specificity: Detects mouse NKG2D in direct ELISAs and Western blots. Does not cross-react with recombinant human NKG2D

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Combination of anti-CD25 antibody and poly I:C treatment in pregnant NOD mice may be used as 'pregnancy-related' type 1 diabetes modelJournal of diabetes investigationSeptember 1, 2022Shimada A, Toda K, Inoue I, Yamada T, Oikawa Y.

(2) NKG2D ligand RAE1ε induces generation and enhances the inhibitor function of myeloid-derived suppressor cells in miceJournal of cellular and molecular medicineSeptember 1, 2017Qian L, Liu Y, Wang S, Gong W, Jia X, Liu L, Ye F, Ding J, Xu Y, Fu Y, et al.

(3) NKG2D-dependent activation of dendritic epidermal T cells in contact hypersensitivityThe Journal of investigative dermatologyMay 1, 2015Nielsen MM, Dyring-Andersen B, Schmidt JD, Witherden D, Lovato P, Woetmann A, Ødum N, Poulsen SS, Havran WL, Geisler C, et al.

(4) HkRP3 is a microtubule-binding protein regulating lytic granule clustering and NK cell killingJournal of immunology (Baltimore, Md. : 1950)April 15, 2015Ham H, Huynh W, Schoon RA, Vale RD, Billadeau DD.

(5) NKG2D triggers cytotoxicity in murine epidermal γδ T cells via PI3K-dependent, Syk/ZAP70-independent signaling pathwayThe Journal of investigative dermatologyFebruary 1, 2014Ibusuki A, Kawai K, Yoshida S, Uchida Y, Nitahara-Takeuchi A, Kuroki K, Kajikawa M, Ose T, Maenaka K, Kasahara M, et al.

(6) CEACAM1 on activated NK cells inhibits NKG2D-mediated cytolytic function and signalingEuropean journal of immunologySeptember 1, 2013Hosomi S, Chen Z, Baker K, Chen L, Huang YH, Olszak T, Zeissig S, Wang JH, Mandelboim O, Beauchemin N, et al.

(7) CX3CL1 expression in the conjunctiva is involved in immune cell trafficking during toxic ocular surface inflammationMucosal immunologyNovember 1, 2012Denoyer A, Godefroy D, Célérier I, Frugier J, Riancho L, Baudouin F, Rostène W, Baudouin C.

(8) Small intestinal intraepithelial lymphocytes expressing CD8 and T cell receptor γδ are involved in bacterial clearance during Salmonella enterica serovar Typhimurium infectionInfection and immunityFebruary 1, 2012Li Z, Zhang C, Zhou Z, Zhang J, Zhang J, Tian Z.

(9) Recombinant mouse cytomegalovirus expressing a ligand for the NKG2D receptor is attenuated and has improved vaccine propertiesThe Journal of clinical investigationDecember 1, 2010Slavuljica I, Busche A, Babić M, Mitrović M, Gašparović I, Cekinović D, Markova Car E, Pernjak Pugel E, Ciković A, Lisnić VJ, et al.

(10) Bortezomib treatment and regulatory T-cell depletion enhance the antitumor effects of adoptively infused NK cellsBloodJune 11, 2009Lundqvist A, Yokoyama H, Smith A, Berg M, Childs R.

(11) Two novel NKG2D ligands of the mouse H60 family with differential expression patterns and binding affinities to NKG2DJournal of immunology (Baltimore, Md. : 1950)February 1, 2008Takada A, Yoshida S, Kajikawa M, Miyatake Y, Tomaru U, Sakai M, Chiba H, Maenaka K, Kohda D, Fugo K, et al.

(12) Activation of immature hepatic NK cells as immunotherapy for liver metastatic diseaseJournal of immunology (Baltimore, Md. : 1950)December 1, 2007Bahjat KS, Prell RA, Allen HE, Liu W, Lemmens EE, Leong ML, Portnoy DA, Dubensky TW Jr, Brockstedt DG, Giedlin MA.

(13) T regulatory cells control numbers of NK cells and CD8alpha+ immature dendritic cells in the lymph node paracortexJournal of immunology (Baltimore, Md. : 1950)October 1, 2007Giroux M, Yurchenko E, St-Pierre J, Piccirillo CA, Perreault C.

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NKG2D/CD314 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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NKG2D/CD314 Antibody from R&D Systems, a Bio-Techne Brand

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