CD4 Antibody MAB554-100 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemCD4 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberMAB554-100
Quantity100 ug (also 500 ug, 25 ug)
ApplicationsFlow Cytometry, Immunohistochemistry, Immunoprecipitation, Cell depletion, Costimulation of T Cells, Inhibition of T Cell Function, CyTOF-ready
Conjugate/TagUnconjugated
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ReactivityMouse
TargetCD4
IsotypeIgG2b
CloneGK1.5
HostRat
ImmunogenMouse CTL clone V4
NCBI Full Gene NameCD4 antigen
NCBI Gene AliasesL3T4, Ly-4
ClonalityMonoclonal
Brand/TrademarkR&D Systems, a Bio-Techne Brand
PurityProtein A or G purified from hybridoma culture supernatant
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Unconjugated

Specificity: Reacts with mouse CD4, an antigen co-receptor on the T cell surface which interacts with MHC II molecules on antigen presenting cells

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Eggerthella lenta augments preclinical autoantibody production and metabolic shift mimicking senescence in arthritisScience AdvancesSeptember 1, 2023Baskar Balakrishnan, David Luckey, Kerry Wright, John M. Davis, Jun Chen, Veena Taneja

(2) CD4(+) T cells aggravate hemorrhagic brain injuryScience advancesJune 9, 2023Shi SX, Xiu Y, Li Y, Yuan M, Shi K, Liu Q, Wang X, Jin WN.(15365-1-AP, Proteintech), anti-human Foxp3 (12632, Cell Signaling Technology), anti-mouse CD4 (GK1.5, MAB554-100, R&D Systems), anti-mouse CD8 (EPR20305, ab209775, Abcam), anti-human/mouse CD19 (6OMP31, 14-0194-82,

(3) Alzheimer's disease protease-containing plasma extracellular vesicles transfer to the hippocampus via the choroid plexusEBioMedicineMarch 1, 2022Lee JH, Ostalecki C, Oberstein T, Schierer S, Zinser E, Eberhardt M, Blume K, Plosnita B, Stich L, Bruns H, et al.

(4) Survival of Stem Cells and Progenitors in the Intestine Is Regulated by LPA₅-Dependent SignalingCellular and molecular gastroenterology and hepatologyJanuary 1, 2022Liang Z, He P, Han Y, Yun CC.

(5) Chronic mild hypoxia accelerates recovery from preexisting EAE by enhancing vascular integrity and apoptosis of infiltrated monocytesProceedings of the National Academy of Sciences of the United States of AmericaMay 19, 2020Halder SK, Milner R.

(6) Interleukin-12p35 Deficiency Reverses the Th1/Th2 Imbalance, Aggravates the Th17/Treg Imbalance, and Ameliorates Atherosclerosis in ApoE-/- MiceMediators of inflammationJanuary 1, 2019Huang Y, Hu H, Liu L, Ye J, Wang Z, Que B, Liu W, Shi Y, Zeng T, Shi L, et al.

(7) Hypoxic pre-conditioning suppresses experimental autoimmune encephalomyelitis by modifying multiple properties of blood vesselsActa neuropathologica communicationsSeptember 3, 2018Halder SK, Kant R, Milner R.

(8) Combination of CD40 Agonism and CSF-1R Blockade Reconditions Tumor-Associated Macrophages and Drives Potent Antitumor ImmunityCancer immunology researchDecember 1, 2017Wiehagen KR, Girgis NM, Yamada DH, Smith AA, Chan SR, Grewal IS, Quigley M, Verona RI.

(9) The efficacy of combination therapy with oncolytic herpes simplex virus HF10 and dacarbazine in a mouse melanoma modelAmerican journal of cancer researchJanuary 1, 2017Tanaka R, Goshima F, Esaki S, Sato Y, Murata T, Nishiyama Y, Watanabe D, Kimura H.

(10) PAX7 expression defines germline stem cells in the adult testisThe Journal of clinical investigationSeptember 1, 2014Aloisio GM, Nakada Y, Saatcioglu HD, Peña CG, Baker MD, Tarnawa ED, Mukherjee J, Manjunath H, Bugde A, Sengupta AL, et al.

(11) Oncolytic viral therapy with a combination of HF10, a herpes simplex virus type 1 variant and granulocyte-macrophage colony-stimulating factor for murine ovarian cancerInternational journal of cancerJune 15, 2014Goshima F, Esaki S, Luo C, Kamakura M, Kimura H, Nishiyama Y.

(12) Extracellular adenosine signaling induces CX3CL1 expression in the brain to promote experimental autoimmune encephalomyelitisJournal of neuroinflammationAugust 10, 2012Mills JH, Alabanza LM, Mahamed DA, Bynoe MS.

(13) CXCR3-dependent recruitment of antigen-specific T lymphocytes to the liver during murine cytomegalovirus infectionJournal of virologyFebruary 1, 2007Hokeness KL, Deweerd ES, Munks MW, Lewis CA, Gladue RP, Salazar-Mather TP.

(14) Blockade of experimental atopic dermatitis via topical NF-kappaB decoy oligonucleotideThe Journal of investigative dermatologyAugust 1, 2006Dajee M, Muchamuel T, Schryver B, Oo A, Alleman-Sposeto J, De Vry CG, Prasad S, Ruhrmund D, Shyamsundar R, Mutnick D, et al.

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CD4 Antibody

CD4 Antibody

CD4 Antibody

CD4 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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CD4 Antibody from R&D Systems, a Bio-Techne Brand

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