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Anti-KPNA2 antibody
Anti-KPNA2 antibody from Abcam
Be the first to write a review!
Citations:
(22)
Supplier Page
Supplier Page from
Abcam for
Anti-KPNA2 antibody
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Anti-KPNA2 antibody
Company
Abcam
Price
Pricing Info
Supplier Page
View Company Product Page
Catalog Number
ab84440
Antibody Type
Primary
Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Clonality
Polyclonal
Conjugate/Tag
Unconjugated
Isotype
IgG
Host
Rabbit
Quantity
100 UL
Gene Name
KPNA2
Reactivity
Human, Mouse
Target
KPNA2
Add to Compare List
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB2 0AX
United Kingdom
Phone
: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600
Company Profile
Website:
http://www.abcam.com
Citations (22)
(1)
Identification and Characterization of Cancer-Associated Fibroblast Subpopulations in Lung Adenocarcinoma
Cancers (Basel)
July 18, 2022
Daeseung Kim et al.
instructions. The sections were incubated with primary antibodies against rabbit polyclonal KPNA2 (
1:200
,
ab84440
;
Abcam
, Cambridge, UK) overnight at 4 °C. Antibody binding was visualized with an ImmPACT DAB Peroxidase
(2)
SARS-CoV-2 ORF6 disrupts nucleocytoplasmic trafficking to advance viral replication
Communications biology
May 19, 2022
Miyamoto Y, Itoh Y, Suzuki T, Tanaka T, Sakai Y, Koido M, Hata C, Wang CX, Otani M, Moriishi K,
et al
.
[58D6],
Cell Signaling Technology
(CST) Inc., Danvers, MA, USA),
STAT1
(#
9172
,
CST
), importin α1/KPNA2 (
ab84440
,
Abcam
, Cambridge, MA, USA; #610486, Anti-Karyopherin α (Rch1), BD Transduction Lab., San Jose, CA,
(3)
Long non-coding RNA HAGLROS facilitates tumorigenesis and progression in hepatocellular carcinoma by sponging miR-26b-5p to up-regulate karyopherin α2 (KPNA2) and inactivate p53 signaling
Bioengineered
March 16, 2022
Gaofeng Tang, Huibo Zhao, Zhantao Xie, Sidong Wei, Guoyong Chen
were cut into 4-μm-thick section, deparaffinized and incubated with antibody against KPNA2 (
Abcam
; Cat#
ab84440
), p53 (
Abcam
; Cat#
ab32389
),
p21
(
Cell Signaling Technology
, Cat#
2947
), PCNA (
Abcam
; Cat#
ab92729
) overnight
(4)
KPNA2 interaction with CBX8 contributes to the development and progression of bladder cancer by mediating the PRDM1/c-FOS pathway
Journal of Translational Medicine
December 1, 2021
Fanchang Zeng, Liumei Luo, Daoyuan Li, Juncheng Guo, Min Guo
and then probed with the following diluted primary antibodies: rabbit polyclonal antibodies to KPNA2 (
ab84440
,
1:1000
,
Abcam
Inc., Cambridge, UK),
CBX8
(
ab70796
,
1:500
,
Abcam
),
PRDM1
(
ab119401
,
1:1000
,
Abcam
),
(5)
Adaptor protein APPL1 links neuronal activity to chromatin remodeling in cultured hippocampal neurons
Journal of Molecular Cell Biology
August 18, 2021
Yu Wu et al.
(
4370S
) and anti-
GAPDH
(
2118
) from
Cell Signaling
Techonology, anti-HDAC2 (
ab32117
), anti-Importin α1 (
ab84440
), anti-Histone H4K5 (
ab51997
), anti-Histone H4K12 (
ab177793
), anti-APPL2 (
ab95196
), and anti-Histone
(6)
Increased Nuclear Transporter KPNA2 Contributes to Tumor Immune Evasion by Enhancing PD-L1 Expression in PDAC
Journal of immunology research
January 1, 2021
Zhou KX, Huang S, Hu LP, Zhang XL, Qin WT, Zhang YL, Yao LL, Yu Y, Zhou YQ, Zhu L,
et al
.
according to previously reported literature [14]. Primary antibodies used are as follows: KPNA2 (
Abcam
,
ab84440
), p-STAT3 (
CST
,
9145S
),
CD8
(
Abcam
,
ab217344
), and Granzyme B (Immunoway, YT6137). 2.5. Proliferation
(7)
Retracted Article: LncRNA SNHG5 regulates the cell viability and apoptosis of glioma cells by the miR-1297/KPNA2 axis
RSC Advances
January 7, 2020
Xueyuan Li, Qiankun Liu, Kang Wang, Wenzheng Luo, Tiansong Liang, Shanpeng Yuan, Yingwei Zhen, Dongming Yan
anti-
caspase-3
(
ab197202
), anti-LC3 (
ab225383
), anti-Beclin-1 (
ab207612
), anti-p62 (
ab109012
), anti-KPNA2 (
ab84440
), and anti-
GAPDH
(
ab181602
) (
Abcam
, Cambridge, MA, USA).
Luciferase reporter assay
A wild-type (WT)
(8)
Immunohistochemical Study of KPNA2 Expression in Correlation to PCNA Expression in Colorectal Carcinoma
The Medical Journal of Cairo University
September 1, 2019
MARYAM E. ABDO, M.Sc.; HEBA F. HARRAS, M.D., OMNIA K. RIZK, M.D.; KHAIRIA GAWEESH, M.D.
immunohistochemically labeled, using primary antibodies to KPNA2 (rabbit polyclonal antibody, Kit no.
ab84440
,
Abcam
, UK, dilution
1:150
) and PCNA (mouse monoclonal antibody,
clone
number (PC 10), Kit no.
AB29
,
Abcam
,
(9)
Nuclear pore heterogeneity influences HIV-1 infection and the antiviral activity of MX2
eLife
August 7, 2018
Kane M, Rebensburg SV, Takata MA, Zang TM, Yamashita M, Kvaratskhelia M, Bieniasz PD.
,
Novus Biologicals
,
NBP2-21596
CPSF6
,rabbit,
ProteinTech
,
15489–1-AP
CPSF6
,rabbit,
Abcam
,
ab175237
ELYS,
mouse
,
Abcam
,
ab53540
GAPDH
,
mouse
,
Santa Cruz
,
sc-32233
KPNA1
,rabbit,
ProteinTech
,
18137–1-AP
KPNA2,rabbit,
Abcam
,
ab84440
LAMIN B1,rabbit,
Abcam
,
ab133741
MX2,rabbit,Novus Biologicals,NBP1-8108 MYCtag,
mouse
,
Millipore
,
05–724
NDC1
,rabbit,
Novus Biologicals
(10)
MicroRNA-302 Cluster Downregulates Enterovirus 71–Induced Innate Immune Response by Targeting KPNA2
The Journal of Immunology
July 1, 2018
Nanfang Peng et al.
infectious dose/ml = 0.69 PFU/ml, as described previously (14). Reagents Abs against
human
KPNA2 (
ab84440
),
human
b-tubulin (
ab6046
),
human
Lamin B (
ab133741
),
human
JNK1
(
ab110724
),
human
JNK2 (
ab76125
),
human
(11)
Regulation of inflammatory responses by dynamic subcellular localization of RNA-binding protein Arid5a
Proceedings of the National Academy of Sciences
February 6, 2018
Mitsuru Higa, Masahiro Oka, Yoshitaka Fujihara, Kazuya Masuda, Yoshihiro Yoneda, Tadamitsu Kishimoto
(customized antibody; Sigma-Aldrich), anti–Regnase-1 (
sc-515275
;
Santa Cruz Biotechnology
), anti-KPNA2 (
ab84440
;
Abcam
), anti–Lamin-B (
PM064
;
MBL
), anti–α-tubulin (M175; MBL), anti-UPF1 (
sc-166092
;
Santa Cruz Biotechnology
),
(12)
Overexpression of karyopherin-α2 in cholangiocarcinoma correlates with poor prognosis and gemcitabine sensitivity via nuclear translocation of DNA repair proteins
Oncotarget
June 27, 2017
Mariko Tsukagoshi et al.
USA) for 30 min. The sections were then incubated with rabbit anti-KPNA2 polyclonal antibody (
1:400
;
ab84440
, anti-KPNA2 antibody,
Abcam
, Cambridge, England), anti-MRE11 rabbit monoclonal antibody (
1:400
;
ab109623
,
(13)
Development of a pipeline for automated, high-throughput analysis of paraspeckle proteins reveals specific roles for importin α proteins
Scientific Reports
April 1, 2017
Andrew T. Major, Yoichi Miyamoto, Camden Y. Lo, David A. Jans, Kate L. Loveland
antibodies specific to SFPQ and to the longer PSPC1 isoform were used67. Rabbit anti-IMPα2 (
Abcam
, cat#
ab84440
) and
goat
anti-IMPα4 (
Abcam
, cat#
ab6039
) were used to detect IMPα2 and IMPα4, respectively, for
immunofluorescence
.
(14)
Cellular apoptosis susceptibility (CAS) is linked to integrin β1 and required for tumor cell migration and invasion in hepatocellular carcinoma (HCC)
Oncotarget
April 19, 2016
Juliane Winkler et al.
and acetone for 30 sec and incubated with anti-imp-α1 rabbit monoclonal antibody for 1 h at RT (
1:50
,
ab84440
,
Abcam
, Cambridge, UK) and incubated with the corresponding secondary antibody (anti-rabbit MFP488 IgG,
(15)
KPNA2 is a nuclear export protein that contributes to aberrant localisation of key proteins and poor prognosis of breast cancer
British Journal of Cancer
June 9, 2015
A T Alshareeda, O H Negm, A R Green, C C Nolan, P Tighe, N Albarakati, R Sultana, S Madhusudan, I O Ellis, E A Rakha
Novolink Kit-polymer detection system (Leica, Newcastle, UK). Primary antibody used was KPNA2 (
clone
Ab84440
,
Abcam
Ltd, Cambridge, UK) with a dilution of
1 : 400
and 60 min
incubation
. 3-3′Diam-inobenzidine tetrahydrochloride
(16)
Identification and characterization of nuclear and nucleolar localization signals in 58-kDa microspherule protein (MSP58)
Journal of biomedical science
May 16, 2015
Yang CP, Chiang CW, Chen CH, Lee YC, Wu MH, Tsou YH, Yang YS, Chang WC, Lin DY.
In this study we used the following commercial antibodies: HA (HA.11; Babco/Covance), Importin α1 (
ab84440
;
Abcam
), Importin α3 (GTX 106325; GeneTex), Importin α6 (GTX 112203; GeneTex), Importin β (GTX 22811;
(17)
Specific interaction with the nuclear transporter importin α2 can modulate paraspeckle protein 1 delivery to nuclear paraspeckles
Molecular Biology of the Cell
April 15, 2015
Andrew T. Major, Cathryn A. Hogarth, Yoichi Miyamoto, Mai A. Sarraj, Catherine L. Smith, Peter Koopman, Yasuyuki Kurihara, David A. Jans, Kate L. Loveland
Australia).
Immunohistochemistry
Immunohistochemistry
with
anti-PSPC1
(Kuwahara et al., 2006) and anti‑IMPα2 (cat. no.
ab84440
;
Abcam
) antibodies was performed as previously described (Loveland et al., 1999) using 50 mM glycine
(18)
Checkpoint kinase1 (CHK1) is an important biomarker in breast cancer having a role in chemotherapy response
British Journal of Cancer
March 3, 2015
M M Al-kaabi et al.
CK17) and luminal (CK18) cytokeratin, nuclear transport protein importin subunit alpha-2 (KPNA2;
clone
Ab84440
,
Abcam
Ltd, Cambridge, UK) used in dilution of
1 : 400
with 60-min
incubation
; Alshareeda et al, 2014),
(19)
The a-importome of mammalian germ cell maturation provides novel insights for importin biology
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
August 1, 2014
Arash Arjomand, Mark A Baker, Chen Li, Ashley M Buckle, David A Jans, Kate L Loveland, Yoichi Miyamoto
(20)
High nuclear karyopherin α 2 expression is a strong and independent predictor of biochemical recurrence in prostate cancer patients treated by radical prostatectomy
Modern Pathology
January 1, 2014
Katharina Grupp et al.
and in one experiment. The primary antibody specific for KPNA2 (polyclonal; rabbit,
Abcam
; cat. no.
ab84440
; at 1/150 dilution) was applied, slides were deparaffinized and exposed to heatinduced antigen retrieval
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Anti-KPNA2 antibody from Abcam
Supplier Page
View Company Product Page
Pricing Info
Product Specs
Company Info
Citations
Reviews
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