Fig 1: HSP60 processing in frataxin-deficient neurons. Western blot detection of HSP60 precursor (p) and mature (m) forms in crude extracts from Scr, Fxn1 and Fxn2 cells after 5 days of culture without treatment (lanes 1–3) or treated with TAT-MTScs-frataxin at 7 µg/ml (lanes 4–6). Mw markers are indicated. Note that precursor form increases in untreated Fxn1 and Fxn2 cultures and the processing is restored by TAT-MTScs-FXN addition.