MyBioSource.com's ASIC1 Antibody: ATTO 390 is a Mouse monoclonal antibody. The ASIC1 Antibody: ATTO 390 was generated using ASIC, ASIC1, ASIC1a, and asic1b as the antigen. It reacts with Mouse, and Rat. This antibody has been shown to work in applications such as: Immunocytochemistry, Immunohistochemistry, and Western Blot.
Description
Background Info: Detects ~60kDa
Scientific Background: Acid sensing ion channel ASIC1, also designated ACCN2, BNAC2 and ASIC1a, is present in brain as a 4.3-kb transcript with localization to rat dorsal root ganglia. In situ hybridization of rat brain suggests that ASIC1 is most abundant in the main olfactory bulb, cerebral cortex, hippocampal formation, habenula, basolateral amygdaloid nuclei and cerebellum. ASIC1 and H+-gated currents may contribute to the development of fear and anxiety