The TNF alpha Antibody from Rockland Immunochemicals, Inc. is a Rabbit Polyclonal antibody to TNF, and Tumor necrosis factor. This antibody recognizes Homo Sapiens, and Human antigen. The TNF alpha Antibody has been validated for the following applications: EIA, Immunoassay, Microscopy, ELISA, Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
Anti TNF alpha Antibody recognizes TNF alpha (TNF, cachexin, cachectin, tumor necrosis factor-alpha or TNF-α) a cytokine involved in systemic inflammation. TNF alpha is a member of a group of cytokines that stimulate the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by other cell types as well. The primary role of TNF alpha is in the regulation of immune cells. TNF is an endogenous pyrogen that is able to induce fever, apoptotic cell death, sepsis (through IL-1 & IL-6 production), cachexia, inflammation, and to inhibit tumorigenesis and viral replication. Dysregulation of TNF production has been implicated in a variety of human diseases, including Alzheimer's disease, cancer, major depression, and inflammatory bowel disease (IBD). Anti-TNF alpha Antibody is useful for researches interested in TNF/TNFR pathways, apoptosis signaling pathways, and cell proliferation