Fig 1: Expression of select surfaceome proteins from top quartile of gene expression. (A) Primary PSCCs (n = 12) were stained for BSG/CD147 (left), FGFR1 (middle), and SLC16A1/MCT1 (right) proteins; top row demonstrates representative staining patterns. (B) Magnification (20×; scale bar is 50 μm) of representative sections demonstrating nuclear vs. membrane localization. (C) Percent of cells with protein expression at the plasma membrane vs. the nuclear compartment (see Section 2 for details). Tumor samples were labeled by HPV status (blue circle = HPV-neg; red triangle = HPV-pos).
Fig 2: Overall survival association with select surfaceome gene expression. Target genes (A) BSG/CD147, (B) FGFR1, (C) SLC16A1/MCT1 were dichotomized into high and low by the median gene expression value. Kaplan–Meier estimates are shown with log-rank comparison between groups.
Supplier Page from Abcam for Anti-CD147 antibody [8D6]