Anti-p53 (acetyl K120) antibody [10E5] ab78316 from Abcam

Product Specs
ItemAnti-p53 (acetyl K120) antibody [10E5]
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab78316
Antibody TypePrimary
Conjugate/TagUnconjugated
ClonalityMonoclonal
ApplicationsELISA, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Western blot
Clone1000000
HostMouse, Nude mouse
Quantity100 UG
IsotypeIgG1
Concentration1 mg/ml
ModificationsAcetyl-K120
Gene Nametp53
ReactivityHuman
Targetp53

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Abcam

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Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) Metabolic rescue ameliorates mitochondrial encephalo-cardiomyopathy in murine and human iPSC models of Leigh syndromeClinical and translational medicineJuly 1, 2022Yoon JY, Daneshgar N, Chu Y, Chen B, Hefti M, Vikram A, Irani K, Song LS, Brenner C, Abel ED, et al.A13519), p53 (ABclonal, A0263), Acetyl‐p53 (Lys382) (Invitrogen, 710294), Anti‐p53 (acetyl K120) (Abcam, ab78316), cleaved caspase‐3 (Cell Signaling Technology, Asp175), VGluT1(Sigma–Aldrich, ZRB2374), VGAT (Sigma–Aldrich,

(2) Loss of peptidase D binding restores the tumor suppressor functions of oncogenic p53 mutantsCommunications BiologyDecember 8, 2021Lu Yang, Yun Li, Arup Bhattacharya, Yuesheng Zhanginhibit cancer cell growth in vitro and in vivo. Methods Antibodies Anti-acetyl-p53 (K120) (Cat# ab78316), anti-acetyl-p53 (K305) (Cat# ab109396), anti-acetyl-p53 (K386) (Cat# ab52172), and anti-PEPD (Cab#

(3) The hepatic AMPK-TET1-SIRT1 axis regulates glucose homeostasiseLifeNovember 5, 2021Chunbo Zhang, Tianyu Zhong, Yuanyuan Li, Xianfeng Li, Xiaopeng Yuan, Linlin Liu, Weilin Wu, Jing Wu, Ye Wu, Rui Liang, et al.ab26), p53 acetyl 382 (Abcam, Waltham, MA, USA, ab75754), p53 acetyl 120 (Abcam, Waltham, MA, USA, ab78316), FOXO1 (Abcam, Waltham, MA, USA, ab52857), PGC-1α (Abcam, Waltham, MA, USA, ab54481), histone H3(Abcam,

(4) Sirt-1 Regulates Physiological Process and Exerts Protective Effects against Oxidative StressBioMed Research InternationalMarch 23, 2021Lei Liu, Guangyuan Xia, Peifan Li, Yiming Wang, Qian ZhaoAbcam, #ab26; p21, Abcam, #ab109520; p53 (acetyl K382), Abcam, #ab75754; p53 (acetyl K120), Abcam, #ab78316. β-Actin was used as an internal control. The chemiluminescence detection kit ECL (Millipore, USA) was used

(5) A New Regulatory Mechanism Between P53 And YAP Crosstalk By SIRT1 Mediated Deacetylation To Regulate Cell Cycle And Apoptosis In A549 Cell LinesCancer Management and ResearchSeptember 23, 2019Fang Yuan, Jinliang Wang, Ruixin Li, Xiao Zhao, Yuxuan Zhang, Biao Liu, Yonghong Lei, Yi HuAbcam, ab62376), anti-P53 (acetyl K370) (1:1000, Abcam, ab183544), anti-P53 (acetyl K120) (1:100, Abcam, ab78316), anti-YAP (acetyl K494) (1:500, in-house), anti-YAP (acetyl K497) (1:500, in-house), anti-GAPDH (1:5000,

(6) Auranofin Protects Intestine against Radiation Injury by Modulating p53/p21 Pathway and Radiosensitizes Human Colon TumorClinical Cancer ResearchAugust 1, 2019Dhrubajyoti Nag, Payel Bhanja, Randal Riha, Giselle Sanchez Sanchez-Guerrero, Bruce F. Kimler, Terance T. Tsue, Chris Lominska, Subhrajit Sahap21(1:1000) (Catalog no. sc397) (Santa Cruz Biotechnology, Dallas, TX, USA); p53 (acetyl K120) (Catalog no. ab78316, Abcam, Cambridge, MA), Tip60 (phospho S86) (Catalog no. ab73207, Abcam, Cambridge, MA); PERK (1:500)

(7) Molecular Mechanism for Selective Cytotoxicity towards Cancer Cells of Diselenide-Containing Paclitaxel NanoparticlesInternational Journal of Biological SciencesJuly 3, 2019Jing Li et al.incubated in 4% paraformaldehyde for 20 min, 1% of bovine serum albumin was used for cell blocking, p53 (ab78316; Abcam) or LC3-II (ab48394; Abcam) was used for incubation of primary antibodies. The blocking time

(8) Tubastatin A inhibits HDAC and Sirtuin activity rather than being a HDAC6-specific inhibitor in mouse oocytesAging (Albany NY)March 26, 2019Yun-Jung Choi, Min-Hee Kang, Kwonho Hong, Jin-Hoi Kimanti-Cyclin B1-Alexa Fluor® 647 (ab215945, Abcam), Anti-NAT10 (ab194297, Abcam), and anti-acetyl-p53 at K120 (ab78316, Abcam)]. All stained samples were mounted using Vectashield mounting medium containing 4′,6-diamidino-2phenylindole

(9) Acetylation of Cytidine in mRNA Promotes Translation EfficiencyCellDecember 13, 2018Arango D, Sturgill D, Alhusaini N, Dillman AA, Sweet TJ, Hanson G, Hosogane M, Sinclair WR, Nanan KK, Mandler MD, et al.Cat#:ab47915, Abcam) and mouse monoclonal anti-p53 (acetylK120) (1:1000 dilution, clone 10E5, Cat#:ab78316, Abcam) were incubated in a solution containing 2% BSA in 0.05% Tween-20 TBS buffer overnight at 4 °C.

(10) ARID1A-mutated ovarian cancers depend on HDAC6 activityNature Cell BiologyAugust 1, 2017Benjamin G. Bitler et al.antibodies were obtained from the indicated suppliers: mouse anti-acetylated-p53 K120 (Abcam, Cat. No. ab78316, 1:1000 for western blot and 1:100 for IHC), rabbit anti-acetylated-p53 K373 (Abcam, Cat. No. ab62376,

(11) Expression of the MOZ-TIF2 oncoprotein in mice represses senescenceExperimental hematologyApril 1, 2016Anne Largeot, Flor Maria Perez-Campo, Elli Marinopoulou, Michael Lie-a-Ling, Valerie Kouskoff, Georges Lacaud,Western blot,Sigma,SAB4500072,"1/2,000" β-Actin,Western blot,Sigma,A1978,"1/10,000" p53,Western blot,Abcam,ab78316,"1/1,000" p53 k120 Ac,Western blot,Abcam,ab26,"1/1,000" Ty1,ChIP,Diagenode,C15200054,6 μg per IP IgG

(12) p53's choice of myocardial death or survival: Oxygen protects infarct myocardium by recruiting p53 on NOS3 promoter through regulation of p53-Lys(118) acetylationEMBO molecular medicineNovember 1, 2013Rajan Gogna, Esha Madan, Mahmood Khan, Uttam Pati, Periannan Kuppusamy

(13) ING5 is a Tip60 cofactor that acetylates p53 in response to DNA damageCancer researchJune 15, 2013Nansong Liu, Jiadong Wang, Jifeng Wang, Rukai Wang, Zhongle Liu, Yao Yu, Hong Lu

(14) Orphan Nuclear Receptor PNR/NR2E3 Stimulates p53 Functions by Enhancing p53 AcetylationMolecular and Cellular BiologyJanuary 1, 2012Zhi Wen, Dohun Pyeon, Yidan Wang, Paul Lambert, Wei Xu, Paul AhlquistK382 [Upstate catalog no. 04-1146], K320 [Upstate catalog no. 06-1283], and K120 [AbCam catalog no. ab78316]) (1:1,000), mouse anti-total p53 antibody (Calbiochem catalog no. OP43) (1:1,000), rabbit anti-PNR

(15) The Ccr4a (CNOT6) and Ccr4b (CNOT6L) deadenylase subunits of the human Ccr4–Not complex contribute to the prevention of cell death and senescenceMolecular Biology of the CellMarch 15, 2011Saloni Mittal, Akhmed Aslam, Rachel Doidge, Rachel Medica, G. Sebastiaan WinklerCruz), p27/Kip1 (2552, 1:1000 dilution; Cell Signaling Technology, Danvers, MA), p53-K120ac antibody (ab78316, 1:500 dilution; Abcam), and β-actin (AC-15, 1:1000; Sigma, St. Louis, MO). All horseradish peroxidase–conjugated

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Anti-p53 (acetyl K120) antibody [10E5] from Abcam

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Anti-p53 (acetyl K120) antibody [10E5] from Abcam

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