Anti-p53 (phospho S46) antibody [EP42Y] ab76242 from Abcam

Product Specs
ItemAnti-p53 (phospho S46) antibody [EP42Y]
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab76242
Antibody TypePrimary
Conjugate/TagUnconjugated
IsotypeIgG
ClonalityMonoclonal
CloneEP42Y
ApplicationsImmunocytochemistry/ Immunofluorescence, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Immunoprecipitation, Western blot, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Immunoprecipitation, Western blot, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Immunoprecipitation, Western blot
HostRabbit
Quantity10 UL, 40 UL, 100 UL
ModificationsPhospho-S46
Gene Nametp53
ReactivityHuman
Targetp53

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Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) Icaritin inhibits PLK1 to activate DNA damage response in NK/T cell lymphoma and increases sensitivity to GELOX regimeMolecular therapy oncolyticsJune 16, 2022Zhang C, Xu H, Sui X, Chen L, Chen B, Lv H, Wang S, Wang X.Chk2 (#6334, CST); p-Chk2 T68 (#2197, CST); p-Chk2 T387 (ab55319, Abcam); p53 (ab1101, Abcam); p-p53 (ab76242, Abcam); ATM (ab26350, Abcam); p-ATM (ab81292, Abcam); FOXO3a (#12829, CST); γH2Ax (Ab26350, Abcam);

(2) Exercise downregulates HIPK2 and HIPK2 inhibition protects against myocardial infarctionEBioMedicineDecember 1, 2021Zhou Q, Deng J, Yao J, Song J, Meng D, Zhu Y, Xu M, Liang Y, Xu J, Sluijter JP, et al.resource,Source,Identifier,RRID Antibodies,,, HIPK2,Abcam,ab108543,AB_10860868 GAPDH,Bioworld,AP0063,AB_2651132 β-actin,Bioworld,AP0060,AB_2797445 Collagen1,Bioworld,BS1530,AB_1662101 p53,Proteintech,10442-1-AP,AB_2206609 p-p53 S15,CST,9284S,AB_331464 p-p53 S46,Abcam,ab76242,AB_1524137 p-p53 S33,ABclonal,AP0984,AB_2863878 p-p53 T81,ABclonal,AP1253,AB_2893244 CD63,ABclonal,A5271,AB_2766092 Bax,ABclonal,A12009,AB_2861644 Bcl2,Affinity,AF6139,AF6139 Caspase3,ABclonal,A2156,AB_2862975 Cell

(3) Small-molecule probe reveals a kinase cascade that links stress signaling to TCF/LEF and Wnt responsivenessCell Chemical BiologyMay 1, 2021Jiongjia Cheng et al.,Thermo Scientific,Cat#PA5–13045 anti-phospho-S209-TCF3,"Sergei Sokol (Hikasa and Sokol, 2011)",N/A anti-phospho-S46-p53,Abcam,Cat#ab76242 anti-phospho-S15-p53,Cell Signaling,Cat#9284 anti-TCF4,Abcam,Cat#ab217668 anti-TCF4 (for ChIP qPCR),Santa

(4) Caffeic acid phenethyl ester induces apoptosis in colorectal cancer cells via inhibition of survivinTURKISH JOURNAL OF BIOLOGYOctober 13, 2020Ceren SARI, Ceren SÜMER, Figen CELEP EYÜPOĞLUantisurvivin rabbit monoclonal antibody (ab76424), anti-p53 (phosphoS46) rabbit monoclonal antibody (ab76242), anti-p53 (phosphoS15) rabbit polyclonal antibody (ab1431), antiglyceraldehyde 3-phosphate dehydrogenase

(5) Cell type-dependent bimodal p53 activation engenders a dynamic mechanism of chemoresistanceScience advancesDecember 1, 2018Yang R, Huang B, Zhu Y, Li Y, Liu F, Shi J.Santa Cruz Biotechnology; γH2A.X (#06-570) from Millipore; and phospho-ATM (S1981) (#ab81292) and phospho-p53 (S46) (#ab76242) from Abcam. Anti-actin (#A5316) from Sigma-Aldrich was used as a loading control. Mathematical model

(6) MicroRNA-132 induces temozolomide resistance and promotes the formation of cancer stem cell phenotypes by targeting tumor suppressor candidate 3 in glioblastomaInternational Journal of Molecular MedicineNovember 1, 2017Zhen-Xiu Cheng, Wen-Bo Yin, Zhong-Yu Wangtranscription 3 (STAT3; 1:1,000; ab109085), mouse double minute 2 homolog (MDM2; 1:500; ab170880), p53 (1:500; ab76242), MET (1:1,000; ab68141), CD133 (1:500; ab19898), zinc finger protein, X-linked (ZFX; 1:500; ab115998)

(7) Variant 2 of KIAA0101, antagonizing its oncogenic variant 1, might be a potential therapeutic strategy in hepatocellular carcinomaOncotargetJuly 4, 2017Liu L, Liu Y, Chen X, Wang M, Zhou Y, Zhou P, Li W, Zhu F.(10442-1-AP, Proteintech, Chicago, IL, USA), P53 (acetyl K382) (ab75754, Abcam), P53 (phosphor S46) (ab76242, Abcam), BAX (50599-2-Ig, Proteintech), P21 (10355-1-AP, Proteintech). Peroxidase-conjugated anti-goat

(8) Piwil2 Inhibits Keratin 8 Degradation through Promoting p38-Induced Phosphorylation To Resist Fas-Mediated ApoptosisMolecular and Cellular BiologyNovember 1, 2014Siyuan Jiang, Lianfang Zhao, Yilu Lu, Meiling Wang, Yuan Chen, Dachang Tao, Yunqiang Liu, Huaqin Sun, Sizhong Zhang, Yongxin Ma

(9) RECQL4 is essential for the transport of p53 to mitochondria in normal human cells in the absence of exogenous stressJournal of cell scienceMay 15, 2012De S, Kumari J, Mudgal R, Modi P, Gupta S, Futami K, Goto H, Lindor NM, Furuichi Y, Mohanty D, et al.Phosphorylated p53 Ser15: #9284 rabbit polyclonal (Cell Signaling). Phosphorylated p53 Ser46: rabbit monoclonal ab76242 (Abcam). Anti-Bax: rabbit polyclonal sc-493 (Santa Cruz). Anti-Bcl-2: mouse monoclonal 100 (Santa Cruz). Anti-BrdU:

(10) Macrophage migration inhibitory factor inhibits BMP-4 induced apoptosisAdvances in Bioscience and BiotechnologyJanuary 1, 2012Nicholas Matluk, Tamara Adams, Aldona Karaczyn, Joseph Verdianti MIF (Santa Cruz, Cat. sc-20121) (1:1000 dilution), mouse anti p53 (Abcam, Cambridge, MA, Cat. ab76242) (1:500 dilution rabbit anti phospho-S46 p53 (Abcam, Cambridge, MA, Cat. ab76242) (1:500 dilution).

(11) Activation of the aryl hydrocarbon receptor by doxorubicin mediates cytoprotective effects in the heartCardiovascular researchMay 1, 2011Maria Volkova, Monica Palmeri, Kerry S Russell, Raymond R Russell

(12) Immunohistochemistry in diagnostic surgical pathology: contributions of protein life-cycle, use of evidence-based methods and data normalization on interpretation of immunohistochemical stainsInternational journal of clinical and experimental pathologyJanuary 1, 2009Halliday A Idikio

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Anti-p53 (phospho S46) antibody [EP42Y] from Abcam

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Anti-p53 (phospho S46) antibody [EP42Y] from Abcam

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