Anti-PARK7/DJ1 antibody [EP2815Y] ab76008 from Abcam

Product Specs
ItemAnti-PARK7/DJ1 antibody [EP2815Y]
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab76008
Antibody TypePrimary
Quantity10 UL, 40 UL, 100 UL
IsotypeIgG
ClonalityMonoclonal
CloneEP2815Y
ApplicationsFlow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Immunoprecipitation, Western blot, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Immunoprecipitation, Western blot, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Immunoprecipitation, Western blot
HostRabbit
Conjugate/TagUnconjugated
Gene NamePARK7
ValidationKnockOut Validated
ReactivityHuman, Mouse, Rat
TargetPARK7/DJ1

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Abcam

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Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

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Website: http://www.abcam.com

(1) S-Nitrosylation-mediated coupling of DJ-1 with PTEN induces PI3K/AKT/mTOR pathway-dependent keloid formationBurns TraumaDecember 18, 2023Dongming Lv, Zhongye Xu, Pu Cheng, Zhicheng Hu, Yunxian Dong, Yanchao Rong, Hailin Xu, Zhiyong Wang, Xiaoling Cao, Wuguo Deng, et al.chemiluminescence imager (SAGE CREATION, Beijing). The primary antibodies used were rabbit monoclonal anti-DJ1 (ab76008, Abcam), rabbit polyclonal anti-GAPDH (10494–1-AP, Proteintech), rabbit monoclonal anti-BAX (ab32503,

(2) Effects of DJ‑1 on apoptosis and mitophagy of glomerular podocytesExperimental and Therapeutic MedicineAugust 11, 2023Jing Xiao, Junjie Tan, Li Yu, Guosheng Liu, Shengyou Yumilk powder at 25˚C on a shaker for 2 h, after which, dropwise rabbit anti-DJ-1 (1:1,000; cat. no. ab76008; Abcam), rabbit anti-PTEN (1:1,000; cat. no. ab137337; Abcam), rabbit anti-LC3B (1:1,000; cat. no. ab192890;

(3) Type 2 Diabetes Mellitus Makes Corneal Endothelial Cells Vulnerable to Ultraviolet A-Induced Oxidative Damage Via Decreased DJ-1/Nrf2/NQO1 PathwayInvestigative ophthalmology & visual scienceNovember 1, 2022Zhang X, Qiu J, Huang F, Shan K, Zhang C.temperature, PVDF membranes were incubated with the following specific primary antibodies (1:1000): DJ-1 (ab76008; Abcam), Nrf2 (ab137550; Abcam), p-Nrf2 (BS-2013R; Bioss), NQO1 (11451-1-AP; Proteintech), β-actin (4970;

(4) Targeting PARK7 Improves Acetaminophen-Induced Acute Liver Injury by Orchestrating Mitochondrial Quality Control and Metabolic ReprogrammingAntioxidants (Basel)October 28, 2022Jiao Cai, Deqin Kong, Zi Long, Jiangzheng Liu, Rui Liu, Chunxu Haifrom Beijing Qing Ke Biotechnology. The primary antibodies used in this study included PARK7 (Abcam, #ab76008), LC3B (Abcam, #ab192890), P62 (Abcam, #ab109012), Keap1 (Abcam, #ab227828), Nrf2 (Abcam, #ab62352),

(5) DJ â€1 is not a deglycase and makes a modest contribution to cellular defense against methylglyoxal damage in neuronsJournal of NeurochemistryAugust 1, 2022Melissa Conti Mazza, Sarah C. Shuck, Jiusheng Lin, Michael A. Moxley, John Termini, Mark R. Cookson, Mark A. WilsonPVDF membranes using a Trans‐Blot Turbo system (Bio‐Rad). Antibodies to DJ‐1 (Abcam catalog number ab76008, 1:4000 dilution) and β‐actin (Sigma catalog number A1978, 1:40 000 dilution) were applied overnight

(6) DJ-1 Alleviates Neuroinflammation and the Related Blood-Spinal Cord Barrier Destruction by Suppressing NLRP3 Inflammasome Activation via SOCS1/Rac1/ROS Pathway in a Rat Model of Traumatic Spinal Cord InjuryJournal of Clinical MedicineJune 27, 2022Lingxin Cai, Liansheng Gao, Guoqiang Zhang, Hanhai Zeng, Xinyan Wu, Xiaoxiao Tan, Cong Qian, Gao Chencord 2 mm from the center of the injury site (20 μm) was taken and incubated with anti-DJ1 (1:125, AB76008, Abcam, Waltham, MA, USA) and anti-IBa1 (1:500, Abcam AB5076) antibodies at 4 °C overnight, respectively.

(7) DJ-1 promotes osteosarcoma progression through activating CDK4/RB/E2F1 signaling pathwayFrontiers in oncologyJanuary 1, 2022Han Z, Wang L, Wang D, Zhang L, Bi Y, Zheng X, Liu W, Bai G, Wang Z, Wan W, et al.by imaging with a microscope (Leica, Wetzlar, German) and measured with the antibodies against DJ1 (ab76008, Abcam, USA). The IHC stained specimens were assessed independently by three pathologists who were blind

(8) Ciclopirox Olamine Exerts Tumor-Suppressor Effects via Topoisomerase II Alpha in Lung AdenocarcinomaFrontiers in oncologyJanuary 1, 2022Yin J, Che G, Jiang K, Zhou Z, Wu L, Xu M, Liu J, Yan S.sc-7961), Rb (Santa Cruz Biotechnology, sc-102), cyclin D3 (Cell Signaling Technology, 2936), DJ-1 (Abcam, ab76008), phosphorylated-P53 (p-P53) (Cell Signaling Technology, 9286), p-ATR (Cell Signaling Technology, 2853),

(9) PARK7 promotes repair in early steroid-induced osteonecrosis of the femoral head by enhancing resistance to stress-induced apoptosis in bone marrow mesenchymal stem cells via regulation of the Nrf2 signaling pathwayCell Death & DiseaseOctober 13, 2021Fei Zhang, Yanglin Yan, Wuxun Peng, Lei Wang, Tao Wang, Zhihong Xie, Hong Luo, Jian Zhang, Wentao Dongthen incubated overnight at 4 °C with the following primary antibodies: rabbit anti-rat PARK7 (1:5000; ab76008) and mouse anti-rat Nrf2 (1 µg/ml; ab89443; Abcam Cambridge, UK), rabbit anti-rat glyceraldehyde-3-phosphate

(10) One carbon metabolism in human lung cancerTranslational Lung Cancer ResearchJune 1, 2021Sha Yao, Luogen Peng, Omar Elakad, Stefan Küffer, Marc Hinterthaner, Bernhard C. Danner, Alexander von von Hammerstein-Equord, Philipp Ströbel, Hanibal BohnenbergerAntibodies), TYMS (#AB232021, Abcam) and Anti-MTHFD2 (#H00010797-M01, Abnova) were used. Anti-PARK7 (1:1,000, #AB76008, Abcam) was used as loading control (24). Cell viability assay For siRNA viability assay, 25 μL transfection

(11) Psychological distress and lack of PINK1 promote bioenergetics alterations in peripheral blood mononuclear cellsScientific ReportsDecember 1, 2020Mariana Grigoruţă, Ruben K. Dagda, Ángel G. Díaz-Sánchez, Alejandro Martínez-Martínezat 4 °C: SOD1 (Abcam, ab16831, 1:2000, 17 kDa), SOD2 (Abcam, ab13533, 1:5000, 25 kDa), DJ-1 (Abcam, ab76008, 1:5000, 23 kDa), BDNF (Abcam, ab108319, 1:500, 14 and 28 kDa), TOM20 (Santa Cruz, sc11415, 1:500, 17

(12) AITC induces MRP1 expression by protecting against CS/CSE-mediated DJ-1 protein degradation via activation of the DJ-1/Nrf2 axisThe Korean Journal of Physiology & PharmacologyNovember 1, 2020Lingling Xu, Jie Wu, Nini Li, Chengjun Jiang, Yan Guo, Peng Cao, Dianlei WangN-acetylcysteine (NAC) was purchased from Shanghai Huicheng Biotechnology Co., Ltd. (Shanghai, China). Anti-DJ-1 (ab76008), anti-MRP1 (ab260038), anti-Nrf2 (ab62352), anti-HO-1 (ab52947), and anti-GAPDH (ab8245) antibodies

(13) Small-Molecule Activity-Based Probe for Monitoring Ubiquitin C-Terminal Hydrolase L1 (UCHL1) Activity in Live Cells and Zebrafish EmbryosJournal of the American Chemical SocietySeptember 30, 2020Kooij R, Liu S, Sapmaz A, Xin BT, Janssen GMC, van Veelen PA, Ovaa H, Dijke PT, Geurink PP.antibodies: UCHL1 (ab27053, Abcam) for cells, UCHL1 (HPA005993, ATLAS) for zebrafish embryos, PARK7 (ab76008, Abcam) for zebrafish embryos, Tubulin (2148, Cell Signaling) for cells and zebrafish embryos, GAPDH

(14) Effects of 2-MCPD on oxidative stress in different organs of male miceFood and Chemical ToxicologyAugust 1, 2020Katharina Schultrich, Colin J. Henderson, Thorsten Buhrke, Albert Braeuningsaline, 0.1% Tween 20). The following antibodies were used: rabbit monoclonal antibody against PARK7/DJ1 (ab76008; Abcam, Cambridge, UK; 1:5000 dilution), and goat-anti-rabbit-IgG-HRP (HAF008, R&D systems, Minneapolis, Canada;

(15) Psychological Stress Phenocopies Brain Mitochondrial Dysfunction and Motor Deficits as Observed in a Parkinsonian Rat ModelMolecular neurobiologyApril 1, 2020Grigoruţă M, Martínez-Martínez A, Dagda RY, Dagda RK.incubated for 12 h with the primary antibody: DJ-1 (Abcam, Rabbit anti-PARK7/DJ1 antibody [EP2815Y], ab76008, 1:5000, 23 kDa), SOD1 (Abcam, Rabbit anti-Superoxide Dismutase 1 antibody, ab16831, 1:2000, 17 kDa),

(16) Regulation of the 20S Proteasome by a Novel Family of Inhibitory ProteinsAntioxidants & redox signalingMarch 20, 2020Olshina MA, Arkind G, Kumar Deshmukh F, Fainer I, Taranavsky M, Hayat D, Ben-Dor S, Ben-Nissan G, Sharon M.Abcam), antiNQO1 (1:1000, ab28947; Abcam), anti-NRas (1:200, sc31; Santa Cruz), anti-DJ-1 (1:10,000, ab76008; Abcam), antiRhoA (1:200, sc418; Santa Cruz), and anti-RBBP9 (1:1000, 12230-2-AP; Proteintech). Secondary

(17) DJ-1 exerts anti-inflammatory effects and regulates NLRX1-TRAF6 via SHP-1 in strokeJournal of neuroinflammationMarch 9, 2020Peng L, Zhou Y, Jiang N, Wang T, Zhu J, Chen Y, Li L, Zhang J, Yu S, Zhao Y.at 37 °C and incubated with the following primary antibodies overnight at 4 °C: DJ-1 (1:1000, Abcam, ab76008), anti-β-actin (1:3000, Proteintech, 66009-1-Ig), IL-1β (1:200, Boster, PB0055), IL-6 (1:200, Boster,

(18) Correlation between 3-MCPD-induced organ toxicity and oxidative stress response in male miceFood and Chemical ToxicologyFebruary 1, 2020Katharina Schultrich, Colin J. Henderson, Albert Braeuning, Thorsten Buhrkeaccording to (Scharmach et al. 2012) by using a rabbit monoclonal antibody raised against PARK7/DJ1 (ab76008; Abcam, Cambridge, UK) in 1:5000 dilution, and goat-anti-rabbit-IgG-HRP (HAF008, R&D systems, Minneapolis,

(19) Sodium Benzoate Attenuates Secondary Brain Injury by Inhibiting Neuronal Apoptosis and Reducing Mitochondria-Mediated Oxidative Stress in a Rat Model of Intracerebral Hemorrhage: Possible Involvement of DJ-1/Akt/IKK/NFκB PathwayFrontiers in Molecular NeuroscienceApril 30, 2019Weilin Xu, Tao Li, Liansheng Gao, Cameron Lenahan, Jingwei Zheng, Jun Yan, Anwen Shao, Jianmin Zhangwere then fixed on slides and used for IF staining. The primary antibodies were DJ-1 (1:250, Abcam ab76008), caspase-3 (1:200, Abcam ab13847), NeuN (1:500, Abcam ab177487). Additionally, TUNEL (Roche Inc., Basel,

(20) Natrium Benzoate Alleviates Neuronal Apoptosis via the DJ-1-Related Anti-oxidative Stress Pathway Involving Akt Phosphorylation in a Rat Model of Traumatic Spinal Cord InjuryFrontiers in Molecular NeuroscienceFebruary 22, 2019Liansheng Gao et al.with Tris-buffered saline and Tween 20, specific primary antibodies including anti-DJ-1 (1:20,000, ab76008, Abcam, Cambridge, United Kingdom), anti-oxDJ-1 (1:5000, ab169520, Abcam), anti-p-Akt (1:2000, CST#4060s,

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Anti-PARK7/DJ1 antibody [EP2815Y] from Abcam

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Anti-PARK7/DJ1 antibody [EP2815Y] from Abcam

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