Fig 1: The expression of PDGFB is significantly increased after SCI or macrophages M2 polarization. (A) Western blot was used to detect the expression levels of PDGFB, PDGFD and PDGFRβ before (Pre) and at 3, 7, and 14 dpi in the injury core of mice (n = 5 per group). (B) Quantitative analysis of PDGFB in (A). The blots were quantified as previously described. **p < 0.01, *p < 0.05 (3 and 7 dpi vs. pre); ### p < 0.001, ## p < 0.01 (3 and 7 dpi vs. 14 dpi). (C) Quantitative analysis of PDGFD in (A). ****p < 0.0001 (3, 7, and 14 dpi vs. pre). (D) Quantitative analysis of PDGFRβ in (A). ***p < 0.001 (7, 14 dpi vs. pre and 3 dpi). (E) Western blot was used to detect the expression levels of PDGFB in M0, M1 or M2 macrophages (n = 5 per group). (F) Quantitative analysis of PDGFB in (E), the blots were quantified as previously described, **p < 0.01 (M2 vs. M0), ### p < 0.001 (M2 vs. M1). (G) ELISA was used to detect the concentration of PDGFB in CM0, CM1 or CM2 (n = 5 per group), The results were expressed as mean ± SD. **p < 0.01 (CM2 vs. other groups).