Description
Product Characteristics: TRIP4, thyroid hormone receptor interactor 4, ASC-1, ASC1, HsT17391, TR-interacting protein 4, TRIP-4, activating signal cointegrator 1, thyroid receptor interacting protein 4, thyroid receptor-interacting protein 4
Target Information: Transcription coactivator of nuclear receptors which functions in conjunction with CBP-p300 and SRC-1 and may play an important role in establishing distinct coactivator complexes under different cellular conditions. Plays a pivotal role in the transactivation of NF-kappa-B, SRF and AP1. Acts as a mediator of transrepression between nuclear receptor and either AP1 or NF- kappa-B. Plays a role in androgen receptor transactivation and in testicular function (By similarity)