Description
Product Characteristics:
The REL gene encodes c-Rel, a transcription factor that is a member of the Rel/NFKB family, which also includes RELA (MIM 164014), RELB (604758), NFKB1 (MIM 164011), and NFKB2 (MIM 164012). These proteins are related through a highly conserved N-terminal region termed the 'Rel domain,' which is responsible for DNA binding, dimerization, nuclear localization, and binding to the NFKB inhibitor (MIM 164008) (Belguise and Sonenshein, 2007 [PubMed 18037997]).[supplied by OMIM, May 2008].
Subcellular location: Nucleus
Synonyms: c-Rel phospho S503, c-Rel phospho Ser503, p-c-Rel phospho S503, p-c-Rel S503, Avian reticuloendotheliosis, C REL, C Rel protein, c Rel proto oncogene protein, Oncogene REL, Oncogene REL avian reticuloendotheliosis, REL, v rel avian reticuloendotheliosis viral oncogene homolog, v rel reticuloendotheliosis viral oncogene homolog.
Target Information: component of the NF-kappa B complex\, involved in transcriptional activation [RGD, Feb 2006]