Description
Product Characteristics:
The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+-ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May2009].
Subcellular location: Cell membrane
Synonyms: alpha 1 Sodium Potassium ATPase phospho Y260, Na,K-ATPase alpha-1, Na+/K+ ATPase 1, Sodium pump 1, ATP1A4, ATP1AL2, ATP1B, ATP1B1, ATPase Na+/K+ transporting alpha 1 polypeptide, ATPase Na+/K+ transporting alpha 4 polypeptide, ATPase Na+/K+ transporting beta 1 polypeptide, MGC1798, MGC25056, MGC3285, MGC51750, Sodium/potassium dependent ATPase beta 1 subunit, Sodium/potassium transporting ATPase alpha 1 chain, Sodium/potassium transporting ATPase subunit beta 1, alpha 1 Sodium Potassium ATPase.
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