Fig 1: (A) The expression of ATP5A1, ATP5G1/G2/G3 and ATPAF1 was determined using immunohistochemistry in a tissue microarray which included clear cell (ccRCC), papillary (pRCC) and sarcomatoid (sRCC) renal cell carcinoma as well as oncocytoma (ONC) and normal renal (proximal tubules, PT; distal tubules, DT; loop of Henle, LoH; collecting duct, CD) tissue. ccRCC tissues were characterized by lower levels of ATP5A1, ATP5G1/G2/G3, and ATPAF1 compared to other RCC subtypes and normal renal tissue. (B) Kaplan Meier estimates demonstrated significant shorter overall survival in ccRCC patients with high levels of ATPAF1 and ATP5G1/G2/G3.
Fig 2: The expression profile of 29 subunits of the ATP synthase (complex V) was retrieved from NextBio database: 12 genes (ATP5A1, ATP5B, ATPAF1, ATP5C1, ATP5D, ATP5O, ATP5F1, ATP5G1, ATP5G2, ATP5G3, ATP5I, and ATP5S) had distinct expression differences of normal and clear cell renal cell carcinoma tissue in several microarray gene expression studies.
Supplier Page from Abcam for Anti-ATP5G1/G2/G3 antibody [EPR13908]