Anti-Lrp2 / Megalin antibody [CD7D5] ab184676 from Abcam

Product Specs
ItemAnti-Lrp2 / Megalin antibody [CD7D5]
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab184676
Quantity50 UL
ApplicationsImmunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Conjugate/TagUnconjugated
IsotypeIgG1
CloneCD7D5
HostMouse, Nude mouse
Antibody TypePrimary
NCBI Gene AliasesDBS, GP330
ClonalityMonoclonal
Concentration1 mg/ml
Gene NameLRP2
ReactivityMouse
TargetLrp2 / Megalin

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Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) WBP2 restrains the lysosomal degradation of GPX4 to inhibit ferroptosis in cisplatin-induced acute kidney injuryRedox BiologySeptember 1, 2023Zebin Deng, Yilong Wang, Jiachen Liu, Hao Zhang, Lizhi Zhou, Hao Zhao, Yachun Han, Shu Yan, Zheng Dong, Yinhuai Wang, et al.evaluation. The incorporated antibodies were: WBP2(Proteintech, #12030-1-AP, 1:200), Megalin (Abcam, # ab184676; 1:500), GPX4(Santa Cruz, #sc-166570, 1: 200), Lamp1 (Abmart, #TD7033S, 1: 100), CK18 (AMSBIO, #A01357-1,

(2) GSDMD-dependent neutrophil extracellular traps promote macrophage-to-myofibroblast transition and renal fibrosis in obstructive nephropathyCell death & diseaseAugust 8, 2022Wang Y, Li Y, Chen Z, Yuan Y, Su Q, Ye K, Chen C, Li G, Song Y, Chen H, et al.Anti-Histone H3 (citrulline R2 + R8 + R17) antibody (ab5103, Abcam), anti-F4/80 [CI: A3-1] (ab6640, Abcam), anti-Lrp2/Megalin (ab184676, Abcam), as well as antibodies against α-SMA, collagen I, GSDMD (ab239377), and DAPI were used for immunofluorescence

(3) Functionally Essential Tubular Proteins Are Lost to Urine-Excreted, Large Extracellular Vesicles during Chronic Renal InsufficiencyKidney360July 15, 2021Ryan J. Adam, Mark R. Paterson, Lukus Wardecke, Brian R. Hoffmann, Alison J. KriegelImmunohistochemistry for megalin was performed as previously described (7), with 1:50 megalin antibody (AB184676; Abcam) and 1:100 Texas Red–labeled anti-mouse antibody (T-862, 1:100; Invitrogen). Immunohistochemistry

(4) Notch signaling regulates Akap12 expression and primary cilia length during renal tubule morphogenesisThe FASEB JournalJuly 1, 2020Malini Mukherjee et al.antibodies used in this study include: Aqp2 (1:200, sc-9882, Santa Cruz Biotechnology), Megalin (1:200, ab184676, Abcam), and acetylated-α-tubulin (1:500, T7451, Sigma). Secondary antibodies conjugated with Alexa

(5) Protein kinase C and protein kinase A are involved in the protection of recombinant human glucagon-like peptide-1 on glomeruli and tubules in diabetic ratsJournal of diabetes investigationMay 1, 2019Yin W, Jiang Y, Xu S, Wang Z, Peng L, Fang Q, Deng T, Zhao W, Zhang W, Lou J.(NO) synthase (iNOS; Abcam, ab15323), superoxide dismutase 1 (SOD1; Abcam, ab13498), megalin (Abcam, ab184676), cubilin (Abcam, ab191073), GLP‐1R (Abcam, ab218532), insulin (Abcam, ab7842), podocin (Abcam, ab50339),

(6) Nonmuscle myosin 2 proteins encoded by Myh9, Myh10, and Myh14 are uniquely distributed in the tubular segments of murine kidneyPhysiological reportsDecember 1, 2017Otterpohl KL, Hart RG, Evans C, Surendran K, Chandrasekar I.dilution Myh10, 909901, Biolegend; 1:500 dilution Myh14, 919201, Biolegend; 1:100 dilution Megalin, ab184676, Abcam; 1:200 dilution Uromodulin, PA5‐47706, Thermo Scientific; 1:1000 dilution Calbindin D‐28K, NBP2‐50028,

(7) TMBIM6 (transmembrane BAX inhibitor motif containing 6) enhances autophagy and reduces renal dysfunction in a cyclosporine A-induced nephrotoxicity modelAutophagyJanuary 1, 2015Yadav RK, Lee GH, Lee HY, Li B, Jung HE, Rashid HO, Choi MK, Yadav BK, Kim WH, Kim KW, et al.

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Anti-Lrp2 / Megalin antibody [CD7D5] from Abcam

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Anti-Lrp2 / Megalin antibody [CD7D5] from Abcam

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