Fig 1: Vitro experiments. CCK-8 assay detected the proliferation rate of U87 (A) and U251 cells (B) after co-cultured with Control, sh LILRB1#1, sh LILRB1#2. Transwell results of the Control, sh LILRB1#1, sh LILRB1#2 effect on the migration and invasion of U87 and U251 cells (C-G). ns, P = 0.05; ***, P < 0.001
Fig 2: Immune infiltrates and LILRB1 expression in LGG and GBM are correlated. B cells, CD4+T cells, macrophages, neutrophils, and dendritic cells infiltrations were favorably linked with LILRB1 expression (A). A worse prognosis was associated with greater infiltration of B cells (B), CD4+T cells (C), M2 macrophages (D) and neutrophils (E)
Fig 3: Multivariate Cox analysis of clinical pathological variables and LILRB1 expression. Multivariate Cox analysis of clinical pathological variables and LILRB1 expression for OS (A), DSS (B) and PFI (C). Covariates -LILRB1 expression, age, gender, race, WHO grade and IDH status
Fig 4: MRI images of typical glioma instances showing both low and high LILRB1 expression levels. Scale bars indicate 10 cm (A). Volumes of peritumoral T2WI abnormalities are distributed in low (n = 19) and high (n = 19) expression groups (B). LILRB1 levels are used to group the distribution of maximum spread distances (C). **, P < 0.01; ***, P < 0.001
Fig 5: Differential LILRB1 expression levels in all tumors and correlation with survival in glioma. Differential LILRB1 expression in all cancers between the tumor and adjacent normal tissues (A) and patients with glioma (B) in TCGA. The association between tumor grade and LILRB1 in patients with glioma (C, E). Kaplan-Meier curves of patients with glioma sorted by LILRB1 expression (D, F). ns, P = 0.05; *, P < 0.05; ***, P < 0.001
Supplier Page from Abcam for Anti-LILRB1 antibody [EPR11256]