Bioss Inc.'s NPSR1/GPR154 Polyclonal Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: EIA, Immunoassay, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, Immunohistochemistry - frozen, and Western Blot. The NPSR1/GPR154 Polyclonal Antibody was generated using NPSR1 as the antigen and it reacts with Human.
Description
G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR154 (G-protein coupled receptor 154), also known as NPSR1 (neuropeptide S receptor), GPRA (G-protein coupled receptor for asthma susceptibility) or PGR14, is a 371 amino acid protein that is thought to play a role in autocrine or paracrine signaling pathways. Ubiquitously expressed, GPR154 exists as nine alternatively spliced isoforms. Defects in the gene encoding GPR154 is the cause of asthma-related traits type 2 (ASRT2)