Met Antibody 4560S from Cell Signaling Technology

Product Specs
ItemMet Antibody
CompanyCell Signaling Technology
Price Pricing Info Supplier Page View Company Product Page
Catalog Number4560S
Quantity100 µl
ApplicationsW, IP
ReactivityH, Mk
TargetMet
HostRabbit
NCBI Gene AliasesAUTS9, DA11, DFNB97, HGFR, RCCP2, c-Met
NCBI Full Gene NameMET proto-oncogene, receptor tyrosine kinase
ClonalityPolyclonal
Research AreaRTK
Molecular Weight145

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Novel quinazoline-1,2,3-triazole hybrids with anticancer and MET kinase targeting propertiesScientific ReportsSeptember 6, 2023Motahareh Mortazavi, Masoomeh Eskandari, Fatemeh Moosavi, Tahereh Damghani, Mehdi Khoshneviszadeh, Somayeh Pirhadi, Luciano Saso, Najmeh Edraki, Omidreza Firuzi3126, Cell Signaling, Danvers, MA), and rabbit monoclonal anti-MET (dilution 1:1000, catalogue number: 4560, Cell Signaling, Danvers, MA) overnight at 4 °C. After incubation with secondary antibody (goat anti-rabbit

(2) Water Drop Evaporation on Slippery Liquid-Infused Porous Surfaces (SLIPS): Effect of Lubricant Thickness, Viscosity, Ridge Height, and Pattern GeometryLangmuirMay 9, 2023Rana Üçüncüoğlu, H. Yildirim ErbilSi oil,S-1,129,5.35,87,91,0.487,2.921,3960,2.22,14.6 350 cSt Si oil,S-1,277,7.89,83,99,0.468,2.145,4560,2.27,12.5 350 cSt Si oil,S-1,310,13.06,65,91,0.378,1.856,4860,1.90,27.0 350 cSt Si oil,S-2,37,0.03,97,101,0.529,3.143,3600,2.45,5.8 350

(3) A-to-I edited miR-411-5p targets MET and promotes TKI response in NSCLC-resistant cellsOncogeneMay 5, 2023Giulia Romano, Patricia Le, Giovanni Nigita, Michela Saviana, Lavender Micalo, Francesca Lovat, Daniel del Valle Morales, Howard Li, Patrick Nana-Sinkam, Mario Acunzo(#9275 S), p-ERK1/2 (#9101 S), p-Elk (#9181 S), Akt (#9272 S), ERK1/2 (#4696 S), Elk (#9182 S), c-Met (#4560 S), c-Jun (#9165), and c-Myc (#18583) antibodies were obtained from Cell Signaling Technologies (Danvers,

(4) Preclinical Characterization of XL092, a Novel Receptor Tyrosine Kinase Inhibitor of MET, VEGFR2, AXL, and MERMolecular Cancer TherapeuticsFebruary 1, 2023Jeff Hsu, Colin Chong, Jeffrey Serrill, Levina Goon, Joan Balayan, Eric N. Johnson, Grachelle Lorenzana, Sharon Wu, Kevin G. Leong, Theodore J. Yun, et al.analysis, antibodies used were from Cell Signaling Technology [VEGFR2 (#9698), pAXL (#5724), and cMET (#4560S)], Thermo Fisher Scientific [pVEGFR2 (#44-1047G) and pMET (#44-88G)] and Abcam [AXL (#ab215205)]. For flow cytometry

(5) Development of resistance to FGFR inhibition in urothelial carcinoma via multiple pathways in vitroThe Journal of PathologyFebruary 1, 2023Geoffrey A Pettitt, Carolyn D Hurst, Zubeda Khan, Helen R McPherson, Matthew C Dunning, Olivia Alder, Fiona M Platt, Emma VI Black, Julie E Burns, Margaret A Knowlessc‐13121; Santa Cruz Biotechnology), N‐cadherin (1:500, sc‐59987; Santa Cruz Biotechnology), MET (1:1000, #4560; Cell Signalling Technology), phospho‐Akt (Ser473: 1:1000, #4060; Cell Signaling Technology), phospho‐EGFR

(6) Responses to the Tepotinib in Gastric Cancers with MET Amplification or MET Exon 14 Skipping Mutations and High Expression of Both PD-L1 and CD44Cancers (Basel)July 15, 2022Sung-Hwa Sohn, Hee Jung Sul, Bum Jun Kim, Dae Young Zangusing standard procedures. Commercially available primary antibodies were directed against anti-MET (#4560; 1:1000; Cell Signaling Technology (CST), Danvers, MA, USA), anti-phospho-MET (#3077; 1:1000; CST),

(7) Regulation of growth, invasion and metabolism of breast ductal carcinoma through CCL2/CCR2 signaling interactions with MET receptor tyrosine kinasesNeoplasiaJune 1, 2022Diana Sofía Acevedo et al.cat no.SC-514148) and anti-SRC, or anti-CCR2 and anti-MET (1:100, Cell Signaling Technology, cat no.4560). Samples were incubated with Duolink in situ Probes; anti-rabbit Minus (cat no.DUO92005) and anti-mouse

(8) ERα36-High Cancer-Associated Fibroblasts as an Unfavorable Factor in Triple-Negative Breast CancerCancersApril 15, 2022Nagel A, Popeda M, Muchlinska A, Sadej R, Szade J, Zielinski J, Skokowski J, Niemira M, Kretowski A, Markiewicz A, et al.antibodies were purchased: from Cell Signaling Technology—anti-c-Met-Tyr1234/1235 (#3077), anti-c-Met (#4560), anti-Akt-Ser473 (#4058), anti-Akt (#9272), anti-ERK1/2-Thr202/Tyr204 (#9101), anti-ERK (#4695); from

(9) Tepotinib suppresses proliferation, invasion, migration, and promotes apoptosis of melanoma cells via inhibiting MET and PI3K/AKT signaling pathwaysOncology LettersApril 13, 2022Guifang Jing, Fang Yu, Huandong Xuecaspase 3 (cat. no. 9664T), caspase 3 (cat. no. 14220T), phospho (p)-MET (cat. no. 3077T), MET (cat. no. 4560S), PI3K (cat. no. 4249T), p-AKT (cat. no. 4060T), AKT (cat. no 4685S) GAPDH (cat. no. 5174T; all from

(10) Imidazopyridine hydrazone derivatives exert antiproliferative effect on lung and pancreatic cancer cells and potentially inhibit receptor tyrosine kinases including c-MetScientific ReportsDecember 1, 2021Tahereh Damghani, Fatemeh Moosavi, Mehdi Khoshneviszadeh, Motahareh Mortazavi, Somayeh Pirhadi, Zahra Kayani, Luciano Saso, Najmeh Edraki, Omidreza Firuzi3126, Cell Signaling, Danvers, MA) and rabbit monoclonal anti-MET (dilution 1:1000, catalogue number: 4560, Cell Signaling, Danvers, MA) overnight at 4 °C. After incubation with secondary antibody (goat anti-rabbit

(11) Phosphorylation of slit diaphragm proteins NEPHRIN and NEPH1 upon binding of HGF promotes podocyte repairThe Journal of biological chemistrySeptember 1, 2021Solanki AK, Arif E, Srivastava P, Furcht CM, Rahman B, Wen P, Singh A, Holzman LB, Fitzgibbon WR, Budisavljevic MN, et al.Puromycin were obtained from Sigma-Aldrich. Antibodies against SHP-2 (Cat. No. 3752S), MET (Cat No. 4560S), phospho-MET (Cat. No. 3077S), and FYN (Cat no. 4023) were obtained from Cell Signaling Technologies.

(12) The translocon-associated protein (TRAP) complex regulates quality control of N-linked glycosylation during ER stressScience advancesJanuary 1, 2021Phoomak C, Cui W, Hayman TJ, Yu SH, Zhao P, Wells L, Steet R, Contessa JN.(1:1000; Cell Signaling Technology, Y1135, DA7A8, 3918), anti-MET (1:1000; Cell Signaling Technology, 4560), anti-pMET (1:500; Cell Signaling Technology, Y1234/1235, D26, 3077), anti-EGFR (1:1000; Cell Signaling Technology

(13) Liposomal Delivery of Mitoxantrone and a Cholesteryl Indoximod Prodrug Provides Effective Chemo-immunotherapy in Multiple Solid TumorsACS nanoOctober 27, 2020Mei KC, Liao YP, Jiang J, Chiang M, Khazaieli M, Liu X, Wang X, Liu Q, Chang CH, Zhang X, et al.analyzed using ImageJ v1.5.2 software (NIH, USA). The primary antibodies were used to stain vinculin (#4560, CST, 1: 1000 dilution), IDO-1 (#51851S, CST, 1: 1000 dilution) and GAPDH (#ab8245, Abcam, 1: 5000 dilution).

(14) Blocking c-MET/ERBB1 Axis Prevents Brain Metastasis in ERBB2+ Breast CancerCancers (Basel)October 1, 2020Shailendra K. Gautam et al.primary antibody cocktail, ERBB1 (D38B1; 1:400), ERBB2 (Cat. No. 2242; 1:200), and c-MET (Cat. No. 4560; 1:200, purchased from Cell Signaling technologies, Beverly, MA, USA. The next day, after washing off

(15) Tepotinib Inhibits the Epithelial–Mesenchymal Transition and Tumor Growth of Gastric Cancers by Increasing GSK3β, E-Cadherin, and Mucin 5AC and 6 LevelsInternational Journal of Molecular SciencesAugust 21, 2020Sung-Hwa Sohn, Hee Jung Sul, Bohyun Kim, Bum Jun Kim, Hyeong Su Kim, Dae Young Zanganti-phospho-c-MET (Tyr1234/1235; 1:1000; #3077; Cell Signaling Technology, Danvers, MA, USA), anti-c-MET (1:1000; #4560; Cell Signaling Technology), anti-phospho-ERK (1:1000; #9101; Cell Signaling Technology), anti-ERK (1:1000;

(16) Combinatorial Inhibition of Cell Surface Receptors Using Dual Aptamer-Functionalized Nanoconstructs for Cancer TreatmentPharmaceuticsJuly 21, 2020Hyojin Lee, Tae Hee Kim, Daechan Park, Mihue Jang, Justin J. Chung, Soo Hyun Kim, Sang-Heon Kim, Kwan Hyi Lee, Youngmee Jung, Seung Ja Oh(4561094; Bio-Rad, Hercules, CA, USA), primary antibodies, anti-c-Met (ab51067; Abcam, Cambridge, UK; 4560; Cell Signaling, Massachusetts, USA), anti-nucleolin (ab22578/ ab13541; Abcam), anti-HER2 (SC-08; Santa Cruz

(17) Deciphering MET-dependent modulation of global cellular responses to DNA damage by quantitative phosphoproteomicsMolecular oncologyJune 1, 2020Bensimon A, Koch JP, Francica P, Roth SM, Riedo R, Glück AA, Orlando E, Blaukat A, Aebersold DM, Zimmer Y, et al.cycle‐dependent kinase 2 (CDK2; #2546T), H2AX (#7631S), 11 (#8967), SMC3 (#5696), and MET (#8198S and #4560) antibodies were all obtained from Cell Signaling Technology (Danvers, MA, USA). Histone H2AX Ser139

(18) Single-Molecule Super-Resolution Microscopy Reveals Heteromeric Complexes of MET and EGFR upon Ligand ActivationInternational Journal of Molecular SciencesApril 17, 2020Marie-Lena I.E. Harwardt et al.Phospho-EGF Receptor (Tyr1068) antibody (Cell Signaling Technology, #2234), Met antibody (Cell Signaling Technology, #4560), Phospho-Met (tyr1234/1235) (D26) XP rabbit antibody (Cell Signaling Technology, #3077)) were incubated

(19) Foretinib Inhibits Cancer Stemness and Gastric Cancer Cell Proliferation by Decreasing CD44 and c-MET SignalingOncoTargets and TherapyFebruary 3, 2020Sung-Hwa Sohn, Bohyun Kim, Hee Jung Sul, Bo Youn Choi, Hyeong Su Kim, Dae Young Zanganti-phospho-c-MET (Tyr1234/1235; 1:1000; #3077; Cell Signaling Technology, Danvers, MA, USA), anti-c-MET (1:1000; #4560; Cell Signaling Technology), antiphospho-AKT (1:1000; #4060; Cell Signaling Technology), anti-AKT (1:1000;

(20) Comparative oncogenomics identifies combinations of driver genes and drug targets in BRCA1-mutated breast cancerNature CommunicationsDecember 1, 2019Stefano Annunziato et al.stained for four hours at room temperature using the primary antibody anti-Met (1:1000, Cell Signaling 4560S), anti-phosphoMet (1:1000, Cell Signaling 3077S), anti-Myc (1:1000, Abcam ab32072), or anti-Mcl1 (1:1000,

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Met Antibody

Met Antibody from Cell Signaling Technology

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Cell Signaling Technology

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Met Antibody from Cell Signaling Technology

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