Description
Product Characteristics:
CPXCR1 is widely expressed in fetal tissues, including the tongue, mandible and palate with an unknown function. Cleft palate most commonly occurs as a sporadic multifactorial disorder with a clear but difficult to define genetic component. As a semi-dominant disorder, X-linked cleft palate (CPX) provides a useful model to investigate a congenital defect that is little influenced by non-genetic factors.
Subcellular location: Cytoplasm, Nucleus, Secreted, Extracellular matrix
Synonyms: Cancer/testis antigen 77, CPX chromosome region, candidate 1, CPX candidate region 1 protein, CPX chromosomal region candidate gene 1 protein, CPX chromosomal region candidate gene 1 protein homolog, CPX chromosome region, candidate 1, CT77, Gm1143, CPXCR_HUMAN.
Target Information: This gene is one of several genes identified in a region of the X chromosome associated with an X-linked cleft palate (CPX) disorder. The encoded protein contains a motif similar to a motif found in zinc-finger proteins. Mutation analysis of this gene has not revealed any mutation which causes the CPX disorder. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2011]