Description
Product Characteristics:
This gene encodes a member of the taxilin family. The encoded protein binds to the C-terminal coiled-coil region of syntaxin family members 1A, 3A and 4A, and may play a role in intracellular vesicle trafficking. This gene is up-regulated by lipopolysaccharide and the gene product may be involved in cell cycle regulation. The related mouse protein was also shown to inhibit activating transcription factor 4-mediated transcription and thus regulate bone mass accrual. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009].
Subcellular location: Cytoplasm, Nucleus, Cell membrane
Synonyms: chromosome X open reading frame 15, LSR5, CXorf15, Environmental lipopolysaccharide-responding gene protein, factor inhibiting activating transcription factor 4 ATF4-mediated transcription, Factor inhibiting ATF4-mediated transcription antibody FIAT, Gamma-taxilin, Lipopolysaccharide-specic response protein 5, LSR5, TXLNG, TXLNG_HUMAN.
Target Information: This gene encodes a member of the taxilin family. The encoded protein binds to the C-terminal coiled-coil region of syntaxin family members 1A, 3A and 4A, and may play a role in intracellular vesicle trafficking. This gene is up-regulated by lipopolysaccharide and the gene product may be involved in cell cycle regulation. The related mouse protein was also shown to inhibit activating transcription factor 4-mediated transcription and thus regulate bone mass accrual. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]