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Antibodies
Anti-LC3A/B antibody
Anti-LC3A/B antibody from Abcam
Be the first to write a review!
Citations:
(38)
Supplier Page
Supplier Page from
Abcam for
Anti-LC3A/B antibody
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Anti-LC3A/B antibody
Company
Abcam
Price
Supplier Page
View Company Product Page
Catalog Number
ab62721
Antibody Type
Primary
Isotype
IgG
Host
Rabbit
Applications
Western blot
Quantity
50 UL, 100 UL
Clonality
Polyclonal
Conjugate/Tag
Unconjugated
Concentration
1.3 mg/ml
Gene Name
MAP1LC3A
Reactivity
Rat
Target
LC3A/B
Add to Compare List
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB2 0AX
United Kingdom
Phone
: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600
Company Profile
Website:
http://www.abcam.com
Citations (38)
(1)
Autophagy-mediated NKG2D internalization impairs NK cell function and exacerbates radiation pneumonitis
Frontiers in Immunology
November 24, 2023
Ruiqing Wang, Xinyue Ma, Xinyu Zhang, Dizhi Jiang, Hongyuan Mao, Zerun Li, Yu Tian, Bo Cheng
(#
ab179511
,
Abcam
),
AP2A1
(#
ab189995
,
Abcam
), AP2M1(#
ab75995
,
Abcam
), LAMP2 (#
ab13524
,
Abcam
), LC3 (#
ab62721
,
Abcam
),
NKG2D
(#
ab36136
,
Abcam
), CXCR3 (#ab288437, Abcam). At room temperature, all the
membranes
were
(2)
Trehalose delays postmenopausal osteoporosis by enhancing AKT/TFEB pathway‑dependent autophagy flow in rats
Experimental and Therapeutic Medicine
October 2, 2023
Yongli Wang, Xingcun Li, Hongliang Gao, Qian Lu
cat. no.
bs5137R
),
GAPDH
(
1:2,000
, Multi Sciences cat. no. Mab5465 100), LC3 (
1:1,000
;
Abcam
; cat. no.
ab62721
) and
P62
(
1:1,000
;
Abcam
; cat. no.
ab109012
). Cells underwent three washes with TBST solution (5 min
(3)
METTL3 promotes hyperoxia-induced pyroptosis in neonatal bronchopulmonary dysplasia by inhibiting ATG8-mediated autophagy
Clinics (Sao Paulo)
July 19, 2023
Lili Xu, Zhan Shi, Zhaojun Pan, Rong Wu
blocking with 5% skimmed milk, the
membranes
were incubated with primary antibodies such as antiLC3I/II (
ab62721
,
1:2000
,
Abcam
, USA), antiATG8 (
ab98830
,
1:2000
,
Abcam
, USA), antiNLRP3 (
ab263899
,
1:1000
,
Abcam
, USA),
(4)
Thrombin aggravates hypoxia/reoxygenation injury of astrocytes by activating the autophagy pathway mediated by SPRED2
Experimental and Therapeutic Medicine
August 3, 2021
Xiaoning Wang, Weiwei Lu, Bing Liu, Yunhe Xu
1:1,000
),
SPRED2
(cat. no.
ab153700
;
1:500
), Beclin 1 (cat. no.
ab210498
;
1:1,000
), LC3-II/I (cat. no.
ab62721
;
1:2,000
) and GAPDH (cat. no.
ab181602
;
1:10,000
) overnight at 4˚C (all purchased from
Abcam
). Following
(5)
Propofol Ameliorates ox-LDL-Induced Endothelial Damage Through Enhancing Autophagy via PI3K/Akt/m-TOR Pathway: A Novel Therapeutic Strategy in Atherosclerosis
Frontiers in Molecular Biosciences
June 25, 2021
Hongyi Zhou, Fan Jiang, Yufang Leng
(
12694
),
mTOR
(
2972
;
Cell Signaling
, United States), p-mTOR (
2971
;
Cell Signaling
), LC3-I / II (
1:1,000
;
ab62721
;
Abcam
), Beclin-1 (
1:1,000
;
ab210498
;
Abcam
),
P62
(
1: 1,000
;
ab211324
;
Abcam
),
Bcl-2
(
1:1,000
;
ab218123
;
(6)
High glucose suppresses autophagy through the AMPK pathway while it induces autophagy via oxidative stress in chondrocytes
Cell Death & Disease
June 1, 2021
Ben Wang et al.
OA. Materials and methods Reagents and antibodies Primary antibodies including
p62
(
ab109012
), LC3 (
ab62721
),
B-cell lymphoma
2 (
Bcl-2
,
ab196495
), p16 (
ab51243
),
p21
(
ab109199
) and β-actin (
ab6276
) were acquired
(7)
Inhibition of the Wnt/β‑catenin signaling pathway reduces autophagy levels in complement treated podocytes
Experimental and Therapeutic Medicine
May 9, 2021
Zhaocheng Dong et al.
Santa Cruz Biotechnology, Inc
.), anti-beclin-1 rabbit mAb (
1:50
; cat. no.
ab217179
; Abcam), anti-LC3A/B rabbit pAb (
1:50
; cat. no.
ab62721
;
Abcam
), anti-SQSTM1 mouse mAb (
1:50
; cat. no.
ab109012
; Abcam), anti-β-catenin rabbit mAb (
1:50
; cat.
(8)
Ginsenoside Rg2 protects cardiomyocytes against trastuzumab‑induced toxicity by inducing autophagy
Experimental and Therapeutic Medicine
March 11, 2021
Guang Liu, Xiaoyong Qi, Xingtao Li, Fangyi Sun
anti-beclin 1 (cat. no.
ab210498
), anti-microtubule associated protein 1 light chain 3α (LC3, cat. no.
ab62721
) overnight at 4˚C. All primary antibodies were used at a
1:200
dilution and were purchased from
Abcam
.
(9)
ASPP2
expression predicts the prognosis of patients with hepatocellular carcinoma after transcatheter arterial chemoembolization
Experimental and Therapeutic Medicine
February 24, 2021
Jiaren Mao, Zhongjun Tan, Xiaoqi Pan, Feijian Meng
1:1,000
, cat. no.
ab210498
),
ASPP2
(dilution
1:2,000
, cat. no.
ab181377
), LC3-I (dilution
1:800
, cat. no.
ab62721
), LC3-II (dilution
1:1,000
, cat. no.
ab51520
), cleaved caspase 3 (dilution
1:1,500
, cat. no. ab32042),
(10)
RNA‐binding protein HuR suppresses senescence through Atg7 mediated autophagy activation in diabetic intervertebral disc degeneration
Cell Proliferation
February 1, 2021
Zhenxuan Shao et al.
was purchased from
Proteintech
, primary antibodies against p21WAF1 (
ab86696
),
p62
(
ab240635
), LC3 (
ab62721
), and
Atg7
(
ab223365
) were acquired from
Abcam
, and primary antibodies against
HuR
(#
12582
),
p53
(#
2524
),
(11)
BNIP3 decreases the LPS-induced inflammation and apoptosis of chondrocytes by promoting the development of autophagy
Journal of Orthopaedic Surgery and Research
December 1, 2020
Zetao Ma, Deli Wang, Jian Weng, Sheng Zhang, Yuanshi Zhang
Abcam
), Cleaved caspase3 (
ab49822
,
Abcam
), Cleaved caspase9 (
ab2324
,
Abcam
), Little Computer 3 (LC3) I/II (
ab62721
,
Abcam
), Autophagy-related protein 7 (
ATG7
) (
ab133528
,
Abcam
),
Beclin1
(#
3495S
,
Cell Signaling Technology
,
(12)
miR-512-3p Overcomes Resistance to Cisplatin in Retinoblastoma by Promoting Apoptosis Induced by Endoplasmic Reticulum Stress
Medical science monitor : international medical journal of experimental and clinical research
July 9, 2020
Kong M, Han Y, Zhao Y, Zhang H.
for 1 h. GAPDH was used as an internal control for the detection of
XBP-1
(
ab37152
,
Abcam
), LC3I/II (
ab62721
,
Abcam
), GRP78 (
ab21685
,
Abcam
),
ATF4
(
ab184909
,
Abcam
),
ATF6
(
ab203119
,
Abcam
), IRE1 (
ab37073
,
Abcam
),
(13)
Tubeimoside I induces autophagy in HepG2 cells by activating the AMP‑activated protein kinase signaling pathway
Oncology Letters
May 13, 2020
Chengxu Ruan, Lijuan You, Yingdong Qiu, Xiao Cui, Defeng Wu
ab32047
,
Abcam
), LC3-I (dilution
1:1,000
, cat. no.
ab128025
,
Abcam
), LC3-II (dilution
1:1,000
, cat. no.
ab62721
,
Abcam
) or β-actin (dilution
1:10,000
, cat. no.
ab8227
,
Abcam
) at 4°C overnight. The
membranes
were
(14)
Moderate Fluid Shear Stress Regulates Heme Oxygenase-1 Expression to Promote Autophagy and ECM Homeostasis in the Nucleus Pulposus Cells
Frontiers in cell and developmental biology
January 1, 2020
Chen S, Qin L, Wu X, Fu X, Lin S, Chen D, Xiao G, Shao Z, Cao H.
(
1:500
,
ab41037
;
Abcam
, United Kingdom),
HO-1
(
1:1000
,
10701-1-AP
;
Proteintech
, China), LC3-I/II (
1:1000
,
ab62721
;
Abcam
, United Kingdom), Beclin-1 (
1:1000
,
3738s
;
Cell Signaling Technology
, United States), IFT 88
(15)
Valosin‑containing protein promotes metastasis of osteosarcoma through autophagy induction and anoikis inhibition via the ERK/NF‑κβ/beclin‑1 signaling pathway
Oncology Letters
August 6, 2019
Xin Hua Long, Yun Fei Zhou, Min Lan, Shan Hu Huang, Zhi Li Liu, Yong Shu
ab36047
), ERK (cat. no.
ab79853
), NF‑κβ (cat. no.
ab16502
), beclin‑1 (cat. no.
ab62557
) and LC3 (cat. no.
ab62721
; all
Abcam
; dilution,
1:2,000
) and
GAPDH
(cat. no.
sc‑48166
,
Santa Cruz Biotechnology, Inc
.; dilution,
(16)
Exercise activates lysosomal function in the brain through AMPK-SIRT1-TFEB pathway
CNS Neuroscience & Therapeutics
March 12, 2019
Jun Huang, Xue Wang, Yi Zhu, Zhe Li, Yu-Ting Zhu, Jun-Chao Wu, Zheng-Hong Qin, Min Xiang, Fang Lin
used for immunofluorescence14
and Western blot
experiments:
LAMP1
(
Sigma
; #
SAB3500285
), LC3 (
Abcam
; #
ab62721
), β‐Actin (
Sigma
; #
A5441
), cathepsin D (
SANTA CRUZ
; #
SC‐377299
), Cathepsin L (
Abcam
; #
ab6314
), GAPDH
(17)
Correlation between autophagy levels in peripheral blood mononuclear cells and clinical parameters in patients with chronic obstructive pulmonary disease
Molecular medicine reports
June 1, 2018
Wu Y, Xu B, He X, Wu B, Li Y, Yu G, Tan C, Wang H.
primary antibodies against
microtubule
‑associated proteins 1A/1B light chain 3A (LC3I/II; cat. no.
ab62721
;
1:1,000
), ubiquitin‑binding protein p62 (p62; cat. no.
ab56416
;
1:1,000
) and beclin‑1 (cat. no.
ab207612
,
(18)
The Sineoculis Homeobox Homolog 1 (SIX1) Gene Regulates Paclitaxel Resistance by Affecting Reactive Oxygen Species and Autophagy in Human Hepatocellular Carcinoma Cell Line HepG2
Medical Science Monitor
April 15, 2018
Baowei Li, Shahe Zhao, Ruipeng Geng, Zhongchao Huo, Hui Zhang
Cambridge, MA, USA), b-Actin (#
A5441
,
1: 4,000
,
Sigma-Aldrich
, St. Louis, MO, USA), LC3 (
1: 1,000
;
Abcam
,
ab62721
), p62 (#12-1107,
1: 1,000
; American Research Product, Belmont, MA, USA). TAX inhibited growth of
HepG2 cells
(19)
Sphingosine kinase 2 activates autophagy and protects neurons against ischemic injury through interaction with Bcl-2 via its putative BH3 domain
Cell Death & Disease
July 1, 2017
Dan-Dan Song, Tong-Tong Zhang, Jia-Li Chen, Yun-Fei Xia, Zheng-Hong Qin, Christian Waeber, Rui Sheng
(20)
Local intra-articular injection of resveratrol delays cartilage degeneration in C57BL/6 mice by inducing autophagy via AMPK/mTOR pathway
Journal of Pharmacological Sciences
June 2, 2017
Na Qin, Liwei Wei, Wuyin Li, Wei Yang, Litao Cai, Zhuang Qian, Shufang Wu
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Anti-LC3A/B antibody from Abcam
Supplier Page
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Product Specs
Company Info
Citations
Reviews
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