Description
Product Characteristics:
General factor that plays a major role in the activation of eukaryotic genes transcribed by RNA polymerase II.
Subcellular location: Nucleus
Synonyms: TF2B, TFIIB, Transcription initiation factor IIB, General transcription factor TFIIB, S300-II, GTF2B
Target Information: This gene encodes the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II. [provided by RefSeq, Jul 2008]