Description
Product Characteristics:
Endothelins are endothelium-derived vasoconstrictor peptides.
Subcellular location: Secreted
Synonyms: ET1, QME, PPET1, ARCND3, HDLCQ7, Endothelin-1, Preproendothelin-1, EDN1
Target Information: The protein encoded by this gene is proteolytically processed to release a secreted peptide termed endothelin 1. This peptide is a potent vasoconstrictor and is produced by vascular endothelial cells. Endothelin 1 also can affect the central nervous system. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2009]