Description
Product Characteristics:
Immediate-early transcription factor that controls the initiation of viral lytic gene expression and lytic reactivation from latency. Triggers lytic replication, and initiates a cellular senescence program in epithelial cells. Upregulates human DCR3/TNFRSF6B by directly binding to its receptor.
Synonyms: Replication and transcription activator, Rta, Immediate-early protein Rta, BRLF1
Target Information: Immediate-early transcription factor that controls the initiation of viral lytic gene expression and lytic reactivation from latency. Triggers lytic replication, and initiates a cellular senescence program in epithelial cells. Upregulates human DCR3/TNFRSF6B by directly binding to its receptor. {ECO:0000269:PubMed:17301127, ECO:0000269:PubMed:19098430}