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Anti-TRPC6 antibody
Anti-TRPC6 antibody from Abcam
Be the first to write a review!
Citations:
(20)
Supplier Page
Supplier Page from
Abcam for
Anti-TRPC6 antibody
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Anti-TRPC6 antibody
Company
Abcam
Price
Pricing Info
Supplier Page
View Company Product Page
Catalog Number
ab62461
Antibody Type
Primary
Clonality
Polyclonal
Applications
Immunocytochemistry/ Immunofluorescence, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Western blot
Isotype
IgG
Host
Rabbit
Quantity
100 UG
Conjugate/Tag
Unconjugated
Concentration
1 mg/ml
Gene Name
TRPC6
Reactivity
Human, Mouse
Target
TRPC6
Add to Compare List
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB2 0AX
United Kingdom
Phone
: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600
Company Profile
Website:
http://www.abcam.com
Citations (20)
(1)
Insights into the Regulation of GFR by the Keap1-Nrf2 Pathway
Kidney360
October 1, 2023
Kengo Kidokoro, Hiroyuki Kadoya, David Z. I. Cherney, Megumi Kondo, Yoshihisa Wada, Reina Umeno, Seiji Kishi, Hajime Nagasu, Kojiro Nagai, Takafumi Suzuki,
et al.
Assay
Designs, Ann Arbor, MI);
TRPC5
(
25890-1-AP
; acquired from
Proteintech
, Rosemont, IL); and TRPC6 (
ab62461
; purchased from
Abcam
, Cambridge, United Kingdom). Signals were detected using an enhanced chemiluminescence
(2)
Putative malignant hyperthermia mutation CaV1.1-R174W is insufficient to trigger a fulminant response to halothane or confer heat stress intolerance
Journal of Biological Chemistry
June 29, 2023
Wei Feng, Jose R. Lopez, Shane Antrobus, Jing Zheng, Arkady Uryash, Yao Dong, Donald Beqollari, Roger A. Bannister, Philip M. Hopkins, Kurt G. Beam,
et al.
with primary antibodies: anti-TRPC3, dilution
1:2500
(
ab51560
;
Abcam
), anti-TRPC6, dilution
1:2500
(
ab62461
,
Abcam
), anti-actin, dilution of
1:5000
(SC8432), and secondary fluorescent antibodies (Abcam). The
(3)
Polydatin Ameliorates High Fructose-Induced Podocyte Oxidative Stress via Suppressing HIF-1α/NOX4 Pathway
Pharmaceutics
October 16, 2022
Hong Ding, Chuanfeng Tang, Wei Wang, Ying Pan, Ruiqing Jiao, Lingdong Kong
anti-
NOX4
(
ab133303
,
1:1000
), anti-SDF-1α (
ab18919
,
1:500
), anti-
CXCR4
(
ab124824
,
1:1000
), and anti-TRPC6 (
ab62461
,
1:1000
) and were purchased from
Abcam
(Cambridge, MA, USA). The primary antibody of anti-glyceraldehyde-3-phosphate
(4)
Role of TRPC6 in periodontal tissue reconstruction mediated by appropriate stress
Stem Cell Research & Therapy
August 5, 2022
Li Wang et al.
density.
Immunohistochemical staining
Immunohistochemical staining
was conducted as previously described [25]. Anti-TRPC6 (
ab62461
;
Abcam
, Cambridge, UK) and anti-COL1 (
ab34710
;
Abcam
, Cambridge, UK) primary antibodies were used. TRAP
(5)
Hsa_circ_0003204 Knockdown Weakens Ox-LDL-Induced Cell Injury by Regulating miR-188-3p/TRPC6 Axis in Human Carotid Artery Endothelial Cells and THP-1 Cells
Frontiers in Cardiovascular Medicine
November 29, 2021
Wenjia Peng, Shuai Li, Shiyue Chen, Jiacheng Yang, Ze Sun
(Solarbio). The
membranes
were blocked in 5% fat-free milk and incubated with primary antibodies anti-TRPC6 (
ab62461
,
Abcam
, Cambridge, MA, USA), anti-
BAX
(
ab104156
,
Abcam
), anti-
BCL2
(
ab194583
,
Abcam
), or anti-β-actin
(6)
Astragaloside IV inhibits palmitic acid-induced apoptosis through regulation of calcium homeostasis in mice podocytes
Molecular Biology Reports
February 19, 2021
Yingjun Zang, Shuang Liu, Aili Cao, Xiangyu Shan, Wenjuan Deng, Zhijun Li, Hao Wang, Yunman Wang, Li Wang, Wen Peng
(
ab216341
,
Abcam
, Cambridge, MA, USA), cytochrome c (
12963S
,
Cell Signaling
, Beverly, MA) or TRPC6 (
ab62461
,
Abcam
, Cambridge, MA, USA) diluted in PBST and then washed three times in PBST and incubated for 1
(7)
Overexpressed lncRNA AC068039.4 Contributes to Proliferation and Cell Cycle Progression of Pulmonary Artery Smooth Muscle Cells Via Sponging miR-26a-5p/TRPC6 in Hypoxic Pulmonary Arterial Hypertension
Shock
February 1, 2021
Yuhan Qin, Boqian Zhu, Linqing Li, Dong Wang, Yong Qiao, Bo Liu, Erfei Luo, Jiantong Hou, Gaoliang Yan, Chengchun Tang
incubated with primary antibody overnight. Antibodies used in the experiment included: anti-TRPC6 antibody (
ab62461
), anti-PCNA antibody (
ab92552
),
anti-Cyclin
A1 (
ab53699
),
anti-Cyclin
D1 (
ab53699
), antiCyclin E1 (
ab133266
)
(8)
Lithium Reduces Migration and Collagen Synthesis Activity in Human Cardiac Fibroblasts by Inhibiting Store-Operated Ca2+ Entry
International Journal of Molecular Sciences
January 15, 2021
Pao-Huan Chen, Cheng-Chih Chung, Yuan-Feng Lin, Yu-Hsun Kao, Yi-Jen Chen
Laboratories, San Jose, CA, USA), TRPC3 (
1:1000
, polyclonal, #
ab51560
,
Abcam
), TRPC6 (
1:1000
, polyclonal, #
ab62461
,
Abcam
), total
Akt
(
1:2000
, monoclonal, #
4685
,
Cell Signaling Technology
, Danvers, MA, USA), phosphorylated
(9)
Tacrolimus ameliorates tubulointerstitial inflammation in diabetic nephropathy via inhibiting the NFATc1/TRPC6 pathway
Journal of cellular and molecular medicine
September 1, 2020
Zhang S, Wang H, Liu Y, Yang W, Liu J, Han Y, Liu Y, Liu F, Sun L, Xiao L.
incubated with primary antibody against anti‐
NFATc1
(Abcam, Cambridge, UK,
ab175134
), anti‐TRPC6 (
Abcam
,
ab62461
), anti‐fibronectin (
Abcam
,
ab2413
), anti‐collagen‐1 (
Affinity
,
AF7001
), anti‐
IL‐6
(
Proteintech
, Wuhan,
(10)
Transient Receptor Potential Cation Channels and Calcium Dyshomeostasis in a Mouse Model Relevant to Malignant Hyperthermia
Anesthesiology
August 1, 2020
Jose Rafael Rafael Lopez, Vikas Kaura, Phillip Hopkins, Xiaochen Liu, Arkady Uryach, Jose Adams, Paul D. Allen
rabbit anti -TRPC3, dilution
1:2500
(
ab51560
;
Abcam
, MA, USA), rabbit anti -TRPC6, dilution
1:2500
(
ab62461
,
Abcam
, MA, USA),
human
anti-actin, dilution of
1:5000
(SC8432; Santa Cruz, CA, USA). All of these antibodies
(11)
miR-135b levels in the peripheral blood serve as a marker associated with acute ischemic stroke
Experimental and Therapeutic Medicine
March 30, 2020
Sha Yang, Xinyu Zhan, Min He, Jingjing Wang, Xuemei Qiu
previously described (22).
Membranes
were incubated with primary antibodies against TRPC6 (cat. no.
ab62461
;
1:1,000
;
Abcam
) and anti-
GAPDH
(cat. no.
2118
;
1:5,000
;
Cell Signaling Technology
, Inc.) overnight
(12)
TRPC6 Attenuates Cortical Astrocytic Apoptosis and Inflammation in Cerebral Ischemic/Reperfusion Injury
Frontiers in cell and developmental biology
January 1, 2020
Liu L, Chen M, Lin K, Xiang X, Yang J, Zheng Y, Xiong X, Zhu S.
antibodies overnight at 4°C:
GFAP
(
1:400
; #
80788S
and #
3670S
;
Cell Signaling Technology
), TRPC6 (
1:100
; #
ab62461
;
Abcam
). Next, the slices were washed with PBS and incubated with secondary fluorescent antibodies (
1:100
;
(13)
Endothelial or vascular smooth muscle cell-specific expression of human NOX5 exacerbates renal inflammation, fibrosis and albuminuria in the Akita mouse
Diabetologia
September 1, 2019
Jay C. Jha, Aozhi Dai, Chet E. Holterman, Mark E. Cooper, Rhian M. Touyz, Chris R. Kennedy, Karin A. M. Jandeleit-Dahm
transient receptor potential cation channel subfamily C member 6 (TRPC-6) (rabbit polyclonal, catalogue no.
ab62461
;
Abcam
). Blots were then incubated with secondary antibodies as follows:
goat
anti-rabbit for
NOX5
,
(14)
Arterial smooth muscle cell PKD2 (TRPP1) channels regulate systemic blood pressure
eLife
December 4, 2018
Bulley S, Fernández-Peña C, Hasan R, Leo MD, Muralidharan P, Mackay CE, Evanson KW, Moreira-Junior L, Mata-Daboin A, Burris SK,
et al
.
monoclonal),
Abcam
,Cat#
ab64085
,WB
1:100
dilution Antibody,anti TRPC6 (rabbit polyclonal),
Abcam
,Cat#
ab62461
,WB
1:1000
dilution
Antibody
,
anti TRPM4 (rabbit polyclonal
),
Abcam
,Cat#
ab106200
,WB
1:500
dilution Antibody,anti
(15)
Aging-related increase in store-operated Ca
2+
influx in human ventricular fibroblasts
American Journal of Physiology-Heart and Circulatory Physiology
July 10, 2018
Momin Mohis, Stacie Edwards, Sean Ryan, Farhan Rizvi, A. Jamil Tajik, Arshad Jahangir, Gracious R. Ross
COOH-terminal antibody (catalog no.
ab188802
,
Abcam
) at
1:100
dilution, and polyclonal anti-TRPC6 antibody (catalog no.
ab62461
,
Abcam
) at
1:200
dilution, respectively. All samples were subjected to
immunoblot
analysis simultaneously. TGF-1
(16)
Role of transient receptor potential channel 6 in the odontogenic differentiation of human dental pulp cells
Experimental and therapeutic medicine
July 1, 2017
Yang X, Song Z, Chen L, Wang R, Huang S, Qin W, Guo J, Lin Z.
5% skim milk solution, the
membranes
were subsequently incubated with anti-TRPC6 antibodies (
1:500
;
ab62461
;
Abcam
, Cambridge, UK), anti-dentin sialophosphoprotein (anti-DSPP) antibodies (
1:500
;
sc73632
;
Santa Cruz
(17)
Natriuretic Peptide Receptor Guanylyl Cyclase-A in Podocytes is Renoprotective but Dispensable for Physiologic Renal Function
Journal of the American Society of Nephrology
January 1, 2017
Janina Staffel, Daniela Valletta, Anna Federlein, Katharina Ehm, Regine Volkmann, Andrea M. Füchsl, Ralph Witzgall, Michaela Kuhn, Frank Schweda
2017 www.jasn.org polyclonal
goat
anti-podocin (
sc-22298
;
Santa Cruz
), polyclonal rabbit anti-TRPC6 (
ab62461
;
Abcam
, Inc.), polyclonal
goat
anti-4-hydroxy-2nonenal antibody (HNE11-S; Alpha Diagnostic International,
(18)
Mechanisms of BDNF regulation in asthmatic airway smooth muscle
American Journal of Physiology-Lung Cellular and Molecular Physiology
August 1, 2016
Bharathi Aravamudan, Michael A. Thompson, Christina M. Pabelick, Y. S. Prakash
(cat. no.
A5316
; dilution:
1:500
), and
TRPC3
(cat. no.
ab188802
; dilution:
1:500
) and TRPC6 (cat. no.
ab62461
; dilution:
1:500
) antibodies were obtained from
Abcam
(Cambridge, MA). Quantikine ELISA kit to estimate
(19)
Mechanosensitive ATP release from hemichannels and Ca²⁺ influx through TRPC6 accelerate wound closure in keratinocytes
Journal of cell science
October 1, 2014
Takada H, Furuya K, Sokabe M.
CX43
(rabbit polyclonal;
3512
,
Cell Signaling Technology
; Danvers, MA) or TRPC6 (rabbit polyclonal;
ab62461
,
Abcam
; Cambridge, UK). Incubations were performed in antibody blocking buffer (10% normal goat serum,
(20)
Identification of TRPC6 as a possible candidate target gene within an amplicon at 11q21-q22.2 for migratory capacity in head and neck squamous cell carcinomas
BMC Cancer
March 14, 2013
Sandra Bernaldo de Quirós, Anna Merlo, Pablo Secades, Iriana Zambrano, Ines Saenz de Santa María, Nerea Ugidos, Eloisa Jantus-Lewintre, Rafael Sirera, Carlos Suarez, María-Dolores Chiara
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Anti-TRPC6 antibody from Abcam
Supplier Page
View Company Product Page
Pricing Info
Product Specs
Company Info
Citations
Reviews
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