PerCP/Cyanine5.5 anti-mouse CD8b (Ly-3) 126610 from BioLegend

Product Specs
ItemPerCP/Cyanine5.5 anti-mouse CD8b (Ly-3)
CompanyBioLegend
Price Pricing Info Supplier Page View Company Product Page
Catalog Number126610
NCBI Gene AliasesCd8b, Ly-3, Ly-C, Lyt-3
IsotypeIgG2b, Kappa
Conjugate/TagPERCP_CYANINE5.5
ApplicationsFlow Cytometry (FC)
ReactivityMouse
CloneYTS156.7.7
HostRat
Quantity100 µg
NCBI Full Gene NameCD8 subunit beta 1
Concentration0.20 mg/mL
FormatPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
ImmunogenMouse thymocytes
Antibody TypePrimary
ClonalityMonoclonal
TargetCD8beta

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BioLegend

8999 BioLegend Way

San Diego, California 92121

United States

Phone: 1-877-246-5343 Toll-Free, USA & Canada
1-858-768-5800 International
Fax: 1-877-455-9587

Company Profile

Website: biolegend.com

(1) Variable staphyloxanthin production by Staphylococcus aureus drives strain-dependent effects on diabetic wound-healing outcomesCell ReportsOctober 19, 2023Amy E. Campbell, Amelia R. McCready-Vangi, Aayushi Uberoi, Sofía M. Murga-Garrido, Victoria M. Lovins, Ellen K. White, Jamie Ting-Chun Pan, Simon A.B. Knight, Alexis R. Morgenstern, Colleen Bianco, et al.stained using CD45 (Clone: 30-F11, BioLegend, Cat 103108), CD8b (clone: YTS156.7.7, BioLegend, Cat 126609), CD11b (clone: M1/70, BioLegend, cat 101235), CD90.2 (clone: 30-H12, BioLegend, cat 105343), Ly6C (clone:

(2) T cell receptor signaling strength establishes the chemotactic properties of effector CD8(+) T cells that control tissue-residencyNature communicationsJuly 4, 2023Abdelbary M, Hobbs SJ, Gibbs JS, Yewdell JW, Nolz JC.450 (1:200; Clone 2F1; Tonbo; Cat# 75-5893-U100), CD8β PerCP/Cy5.5 (Clone YST156.7.7; BioLegend; Cat# 126609), CD69 FITC or Pacific Blue (1:100; Clone H1.2FE, BioLegend; Cat# 104506 or 104523), CD103 PE (1:200;

(3) Fcγ receptor-dependent antibody effector functions are required for vaccine protection against infection by antigenic variants of SARS-CoV-2bioRxivMay 8, 2023Samantha R. Mackin, Pritesh Desai, Bradley M. Whitener, Courtney E. Karl, Meizi Liu, Ralph S. Baric, Darin K. Edwards, Taras M. Chicz, Ryan P. McNamara, Galit Alter, et al.CD45 (BUV395; Clone 30-F11; Cat: 564279; BD Biosciences), CD8β (PerCP/Cy5.5; Clone YTS156.7.7; Cat: 126610; BioLegend), CD4 (FITC; Clone GK1.5; Cat: 100406; BioLegend), CD44 (APC/Cy7; Clone IM7; Cat: 103028;

(4) Targeting PD-L2-RGMb overcomes microbiome-related immunotherapy resistanceNatureMay 1, 2023Park JS, Gazzaniga FS, Wu M, Luthens AK, Gillis J, Zheng W, LaFleur MW, Johnson SB, Morad G, Park EM, et al.YTS156.7.7 (BioLegend Cat#126629 1:200), PerCP-Cy5.5 anti-mouse CD8β clone YTS156.7.7 (BioLegend Cat#126610 1:200), Alexa Flour 700 anti-mouse CD8α clone 53-6.7 (BioLegend Cat#100730 1:200), BUV395 anti-mouse

(5) Inhibition of the mitochondrial pyruvate carrier simultaneously mitigates hyperinflammation and hyperglycemia in COVID-19Science ImmunologyApril 14, 2023Bibo Zhu, Xiaoqin Wei, Harish Narasimhan, Wei Qian, Ruixuan Zhang, In Su Cheon, Yue Wu, Chaofan Li, Russell G. Jones, Mark H. Kaplan, et al.anti-CD4-BV510 (Biolegend, clone RM4–5, Cat# 100559), anti-CD8-PerCP-Cy5.5 (Biolegend, clone YTS156.7.7, Cat# 126610), Influenza NP366 Tetramer (NIH Tetramer Facility, Cat# H-2D(b) ASNENMETM), Influenza PA224 Tetramer

(6) Intestinal tissue-resident T cell activation depends on metabolite availabilityProceedings of the National Academy of SciencesAugust 23, 2022Špela Konjar, Cristina Ferreira, Filipa Sofia Carvalho, Patrícia Figueiredo-Campos, Júlia Fanczal, Sofia Ribeiro, Vanessa Alexandra Morais, Marc Veldhoensheet CD8α,APC,53-6.7,BioLegend,100712,https://www.biolegend.com/en-us/products/apc-anti-mouse-cd8a-antibody-150?GroupID=BLG6765 CD8α,SB600,53-6.7,eBioscience,63-0081-82,https://www.thermofisher.com/antibody/product/CD8a-Antibody-clone-53-6-7-Monoclonal/63-0081-82 CD8α,FITC,53-6.7,BioLegend,100706,https://www.biolegend.com/en-us/search-results/fitc-anti-mouse-cd8a-antibody-153?GroupID=BLG2559 CD8α,BV605,53-6.7,BioLegend,100744,https://www.biolegend.com/en-us/products/brilliant-violet-605-anti-mouse-cd8a-antibody-7636?GroupID=BLG2559 CD44,AF700,IM7,BioLegend,103026,https://www.biolegend.com/en-us/products/alexa-fluor-700-anti-mouse-human-cd44-antibody-3406 CD44,PacificB,IM7,BioLegend,103020,https://www.biolegend.com/en-us/products/pacific-blue-anti-mouse-human-cd44-antibody-3099?GroupID=BLG10425 CD8β,PerCP-Cy5.5,YTS156.7.7,BioLegend,126610,https://www.biolegend.com/en-us/search-results/percp-cyanine5-5-anti-mouse-cd8b-antibody-4477 CD8β,AF647,YTS156.7.7,BioLegend,126612,https://www.biolegend.com/en-us/search-results/alexa-fluor-647-anti-mouse-cd8b-antibody-4478?GroupID=BLG4212 CD4,eF506,RM4-5,Invitrogen,69-0042-82,https://www.thermofisher.com/antibody/product/CD4-Antibody-clone-RM4-5-Monoclonal/69-0042-82 CD4,V500,RM4-5,BD Bioscience

(7) IL-17A Increases Doxorubicin Efficacy in Triple Negative Breast CancerFrontiers in OncologyJuly 18, 2022Nicholas R. Hum, Aimy Sebastian, Kelly A. Martin, Naiomy D. Rios-Arce, Sean F. Gilmore, David M. Gravano, Elizabeth K. Wheeler, Matthew A. Coleman, Gabriela G. Loots103116, 157613), CD3ϵ (1:50; Cat# 100312), CD4 (1:100; Cat# 100414, 100406), CD8b (1:100, Cat# 126622, 126609), CD279 (PD-1) (1:100, Cat# 135213), IL-17A (1:100, Cat# 506922), TCR γ/δ (1:100, Cat# 118107; Miltenyi

(8) ICAM-1-mediated adhesion is a prerequisite for exosome-induced T cell suppressionDevelopmental CellFebruary 1, 2022Wei Zhang, Wenqun Zhong, Beike Wang, Jiegang Yang, Jingbo Yang, Ziyan Yu, Zhiyuan Qin, Alex Shi, Wei Xu, Cathy Zheng, et al.anti-mouse CD3,BioLegend,Cat# 100204; RRID:AB_312661 Rat monoclonal anti-mouse CD8b,BioLegend,Cat# 126610; RRID:AB_2260149 Rat monoclonal anti-mouse CD4,BioLegend,Cat# 100451; RRID:AB_2564591 Mouse monoclonal

(9) Cancer-cell-derived GABA promotes β-catenin-mediated tumour growth and immunosuppressionNature cell biologyFebruary 1, 2022Huang D, Wang Y, Thompson JW, Yin T, Alexander PB, Qin D, Mudgal P, Wu H, Liang Y, Tan L, et al.126614, 1:100 dilution; PerCP/Cyanine5.5 anti-mouse CD8b (Clone YTS156.7.7) antibody, BioLegend Cat# 126610, 1:100 dilution; FITC anti-mouse I-Ab (Clone AF6–120.1) antibody, BioLegend Cat# 116406, 1:100 dilution;

(10) Effector T cell responses unleashed by regulatory T cell ablation exacerbate oral squamous cell carcinomaCell reports. MedicineSeptember 21, 2021Chao JL, Korzinkin M, Zhavoronkov A, Ozerov IV, Walker MT, Higgins K, Lingen MW, Izumchenko E, Savage PA.RRID:AB_2563950" "anti-mouse CD8b (Ly-3) antibody, clone YTS156.7.7, PerCP/Cy5.5 conjugated",BioLegend,"Cat# 126609, RRID:AB_961304" "EGR2 Monoclonal Antibody, clone erongr2, APC conjugated",eBioscience,"Cat# 17-6691-80,

(11) Butyrophilin-like 2 regulates site-specific adaptations of intestinal γδ intraepithelial lymphocytesCommunications biologyJuly 26, 2021Panea C, Zhang R, VanValkenburgh J, Ni M, Adler C, Wei Y, Ochoa F, Schmahl J, Tang Y, Siao CJ, et al.CD8α-AF700 (Biolegend, Clone#53-6.7, Cat#100730), CD8β-PerCP/Cy5.5 (Biolegend, Clone#YTS156.7.7, Cat#126610), TCRβ-BV711 (Biolegend, Clone#H57-597, Cat#109243), TCRβ-APC/Cy7 (Biolegend, Clone#H57-597, Cat#109220),

(12) Uncoupling of macrophage inflammation from self-renewal modulates host recovery from respiratory viral infectionImmunityJune 8, 2021Zhu B, Wu Y, Huang S, Zhang R, Son YM, Li C, Cheon IS, Gao X, Wang M, Chen Y, et al.RM4-5),Biolegend,Cat# 100559; RRID: AB_2562608 Anti CD8-PerCP-Cy5.5(clone YTS156.7.7),Biolegend,Cat# 126610; RRID: AB_2260149 Anti human HLA-DR-PerCP-Cy5.5 (clone L243),Biolegend,Cat# 307630; RRID: AB_893567 Anti

(13) A Single-Dose Intranasal ChAd Vaccine Protects Upper and Lower Respiratory Tracts against SARS-CoV-2CellOctober 1, 2020Hassan AO, Kafai NM, Dmitriev IP, Fox JM, Smith BK, Harvey IB, Chen RE, Winkler ES, Wessel AW, Case JB, et al.AB_2651134 PE anti-CD44,BioLegend,Cat # 103024; RRID: AB_493687 PerCP/Cy5.5 anti-CD8b,BioLegend,Cat # 126610; RRID: AB_2260149 APC/Cy7 anti-CD19,BioLegend,Cat # 115530; RRID: AB_830707 Fixable Aqua dead cell stain

(14) Butyrophilin-like proteins display combinatorial diversity in selecting and maintaining signature intraepithelial γδ T cell compartmentsNature communicationsJuly 28, 2020Jandke A, Melandri D, Monin L, Ushakov DS, Laing AG, Vantourout P, East P, Nitta T, Narita T, Takayanagi H, et al.FITC,GL-2,BD,552143,1:100 TCR Vδ4 PE,GL-2,BioLegend,134905,1:100 CD8β PerCpCy5.5,YTS156.7.7,BioLegend,126610,1:200 TCR Vγ1.1/Cr4 FITC,2.11,BioLegend,141103,1:100 TCR Vγ4 APC,UC3-10A6,BioLegend,137708,1:100 TCRδ

(15) PD-1 Signaling Promotes Control of Chronic Viral Infection by Restricting Type-I-Interferon-Mediated Tissue DamageCell reportsNovember 26, 2019Raju S, Verbaro DJ, Egawa T.RRID:AB_2732919 Anti-CD8a-FITC,Biolegend,CAT#100706; RRID:AB_312745 Anti-CD8b-PerCP-Cy5.5,Biolegend,CAT#126610; RRID:AB_2260149 Anti-EOMES-PerCP-e710,Invitrogen,CAT#46–4875–82; RRID:AB_10597455 Anti-Fas-PE-Cy7,BD,CAT#557653;

(16) PTPN2 regulates the generation of exhausted CD8⁺ T cell subpopulations and restrains tumor immunityNature immunologyOctober 1, 2019LaFleur MW, Nguyen TH, Coxe MA, Miller BC, Yates KB, Gillis JE, Sen DR, Gaudiano EF, Al Abosy R, Freeman GJ, et al.

(17) A Gorilla Adenovirus-Based Vaccine against Zika Virus Induces Durable Immunity and Confers Protection in PregnancyCell reportsSeptember 3, 2019Hassan AO, Dmitriev IP, Kashentseva EA, Zhao H, Brough DE, Fremont DH, Curiel DT, Diamond MS.# 103024 PE/Cy7 anti-mouse anti-CD4,BioLegend,Cat # 100422 PerCP/Cy5.5 anti-CD8b,BioLegend,Cat # 126610 APC/Cy7 anti-CD19,BioLegend,Cat # 115530 Alexa Fluor 488 anti-CD3,BioLegend,Cat # 100210 Fixable

(18) Tumor-intrinsic PIK3CA represses tumor immunogenecity in a model of pancreatic cancerThe Journal of clinical investigationMay 21, 2019Sivaram N, McLaughlin PA, Han HV, Petrenko O, Jiang YP, Ballou LM, Pham K, Liu C, van der Velden AW, Lin RZ.by flow cytometry using different anti-CD4 (BioLegend 116025, clone RM4-4) and anti-CD8 (BioLegend 126610, clone YTS156.7.7) antibodies. The control mouse received PBS injections. On day 4, mice were implanted

(19) A CRISPR-Cas9 delivery system for in vivo screening of genes in the immune systemNature communicationsApril 10, 2019LaFleur MW, Nguyen TH, Coxe MA, Yates KB, Trombley JD, Weiss SA, Brown FD, Gillis JE, Coxe DJ, Doench JG, et al.(1:100 dilution), CD8α Biolegend Cat# 100737 (1:100 dilution), CD8β Biolegend Cat# 126606, 126608, 126610, 126620 (1:100 dilution), c-Kit Biolegend Cat# 135108 (1:100 dilution), F4/80 Biolegend Cat# 123116

(20) A Human Gain-of-Function STING Mutation Causes Immunodeficiency and Gammaherpesvirus-Induced Pulmonary Fibrosis in MiceJournal of virologyFebruary 15, 2019Bennion BG, Ingle H, Ai TL, Miner CA, Platt DJ, Smith AM, Baldridge MT, Miner JJ.system: CD4 (catalog no. 100437; BioLegend), CD8␣ (catalog no. 100734; BioLegend), CD8␤ (catalog no. 126609; BioLegend), CD19 (catalog no. 115528; BioLegend), CD45 (catalog no. 103139; BioLegend), IFN-␥ (catalog

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5/28/2020This BioLegend Antibody Is Great for Identifying CD8b+ T Cells Robert YuanThe antibody is great for identifying the CD8b+ population of T cells.

PerCP/Cyanine5.5 anti-mouse CD8b (Ly-3) from BioLegend

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PerCP/Cyanine5.5 anti-mouse CD8b (Ly-3) from BioLegend

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