Description
Product Characteristics: The HA (human influenza hemagglutinin) epitope tag is frequently engineered onto the N- or C- terminus of a protein of interest so that the tagged protein can be analyzed and visualized using immunochemical methods. The recognized HA epitope represents the amino acid sequence YPYDVPDYA. Synonyms: Monoclonal HA Tag antibody, Anti-HA Tag antibody, Hemagglutinin antibody, HA epitope antibody, HA antibody.
Target Information: Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induce an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore