Anti-Tuberin antibody [EP1107Y] ab52936 from Abcam

Product Specs
ItemAnti-Tuberin antibody [EP1107Y]
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab52936
Antibody TypePrimary
IsotypeIgG
HostRabbit
Quantity10 UL, 40 UL, 100 UL
CloneEP1107Y
ClonalityMonoclonal
ApplicationsFlow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Immunoprecipitation, Western blot, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Immunoprecipitation, Western blot, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Immunoprecipitation, Western blot
Conjugate/TagUnconjugated
Gene NameTSC2
ValidationKnockOut Validated
ReactivityHuman
TargetTuberin

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Abcam

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Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) CBAP regulates the function of Akt-associated TSC protein complexes to modulate mTORC1 signalingJournal of Biological ChemistryDecember 1, 2023Wei-Ting Liao, Yun-Jung Chiang, Hsin-Fang Yang-Yen, Li-Chung Hsu, Zee-Fen Chang, Jeffrey J.Y. Yenimmunoprecipitation or immunoblotting: Akt1/2/3 (pan-Akt; ab179463), p-Akt1 (S473; ab81283), TSC2 (ab52936), and Rheb (ab92313) from Abcam; actin (3700), c-Myc (5650), Myc-tag (2276), TSC2 (4308), p-TSC2 (S939

(2) G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signalingCellFebruary 4, 2021Prentzell MT, Rehbein U, Cadena Sandoval M, De Meulemeester AS, Baumeister R, Brohée L, Berdel B, Bockwoldt M, Carroll B, Chowdhury SR, et al.Switzerland (Molle, 2006). Generated according to van Slegtenhorst et al. (1998).",N/A TSC2 #3,Abcam,Cat# ab52936; RRID: AB_883283 TUBA1B,Abcam,Cat# ab108629; RRID: AB_10866252 VDAC,Cell Signaling,Cat# 4661; RRID:

(3) Mesenchymal Tumorigenesis Driven by TSC2 Haploinsufficiency Requires HMGA2 and Is Independent of mTOR Pathway ActivationCancer researchFebruary 15, 2016D'Armiento J, Shiomi T, Marks S, Geraghty P, Sankarasharma D, Chada K.immunohistochemistry was performed on LAM samples with two additional antibodies (Abcam anti-tuberin (EP1107Y) (ab52936) and Abcam anti-tuberin (Y320) (ab32554)) (a positive tuberin staining for the Y320 antibody is shown

(4) Uterine-specific loss of Tsc2 leads to myometrial tumors in both the uterus and lungsMolecular endocrinology (Baltimore, Md.)September 1, 2013Hen Prizant, Aritro Sen, Allison Light, Sung-Nam Cho, Francesco J DeMayo, John P Lydon, Stephen R Hammes

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Anti-Tuberin antibody [EP1107Y] from Abcam

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Anti-Tuberin antibody [EP1107Y] from Abcam

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