Fig 1: Proposed mechanisms for the effect of CLE in inhibiting degranulation of MCs through the H1R- PKCd signaling pathway.
Fig 2: The mechanism of CLE on MC degranulation related to H1R and PKCδ. (A) Protein expression of H1R, PKCδ, and GAPDH determined by Western blot. (B) H1R protein expression. (C) PKCδ protein expression. (D) H1R mRNA expression. (E) PKCδ mRNA expression. n = 6 in each group. All data are the mean ± SD. ***p < 0.001 vs. the Sham group. # p < 0.05, ### p < 0.001 vs. the I/R group. &&& p < 0.001 vs. the C48/80+I/R group.
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