Fig 1: The contribution of ozone exposure to airway smooth function and Th1/Th2 balance of asthmatic mice. (A–E) The bronchial wall thickness (A), smooth muscle thickness (B), airway resistance (C), lung compliance (D) and Log PC100 Penh (E) of mice was examined among saline+air, saline+ozone, OVA+air and OVA+ozone groups. *: P<0.05 when compared with saline+air group, #: P<0.05 when compared with saline+ozone group, &: P<0.05 when compared with OVA+air group. (F–H) Levels of HA (F), TNF-a (G) and IL-13 (H) were determined within mice of saline+air, saline+ozone, OVA+air and OVA+ozone groups. *: P<0.05 when compared with saline+air group, #: P<0.05 when compared with saline+ozone group, &: P<0.05 when compared with OVA+air group. (I–O) The amounts of IL-5 (I), IL-4 (J), IL-10 (K), IFN-? (L), IL-2 (M), T-bet (N) and GATA3 (O) were determined within mice treated by saline+air, saline+ozone, OVA+air and OVA+ozone. *: P<0.05 when compared with saline+air group, #: P<0.05 when compared with saline+ozone group, &: P<0.05 when compared with OVA+air group.