Anti-ERK1 + ERK2 antibody [ERK-7D8] ab54230 from Abcam

Product Specs
ItemAnti-ERK1 + ERK2 antibody [ERK-7D8]
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab54230
Antibody TypePrimary
HostMouse, Nude mouse
Quantity100 UG
ClonalityMonoclonal
IsotypeIgG1
CloneERK-7D8
ApplicationsImmunocytochemistry/ Immunofluorescence, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Conjugate/TagUnconjugated
Concentration0.5 mg/ml
Gene NameMAPK3
ReactivityHuman, Mouse
TargetERK1 + ERK2

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Abcam

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Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

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Website: http://www.abcam.com

(1) Targeting the up-regulated CNOT3 reverses therapeutic resistance and metastatic progression of EGFR-mutant non-small cell lung cancerCell Death DiscoveryNovember 2, 2023Lin Jing, Meng-En Zhai, Mei-Rui Qian, Yi-Ming Li, Ming-Wei Han, Kun Wang, Wan Huang, Gang Nan, Jian-Li Jiangfrom Abcam (ab30620, Ab16667 and ab134953). The antibodies against ERK1/2 were purchased from Abcam (ab54230) and Cell Signaling Technology (4695). The antibody against mTOR was purchased from Santa Cruz Biotechnology

(2) miR-126 mitigates the osteogenic differentiation of human bone marrow-derived mesenchymal stem cells by targeting the ERK1/2 and Bcl-2 pathwaysActa Biochimica et Biophysica SinicaMarch 25, 2023Ying Zhang, Yiping Dong, Qiushi Wei, Zhikun Zhuang, Youwen Liu, Qiang Yuan, Wei He, Zhenhao Jing, Jitian Li, Peifeng Li, et al.1:2000; Abcam), anti-Bcl-2 (ab59348, 1:5000; Abcam), anti-p-ERK1/2 (ab214362, 1:500; Abcam), anti-ERK1/2 (ab54230, 1:1000; Abcam), anti-β-actin (ab8227, 1:5000; Abcam), and HRP-conjugated goat anti-mouse/rabbit (ab6789/ab6721,

(3) Microbiota dysbiosis influences immune system and muscle pathophysiology of dystrophin-deficient miceEMBO molecular medicineMarch 8, 2023Farini A, Tripodi L, Villa C, Strati F, Facoetti A, Baselli G, Troisi J, Landolfi A, Lonati C, Molinaro D, et al.(1:500, ab179463, Abcam); PPARγ (1:500, AB59256, Abcam); IL‐33 (1:500, af3626, R&D); ERK 1‐2 (1:500, ab54230, Abcam); OPN (1:500, AF808, R&D); MyD88 Innate Immune Signal Transduction Adaptor (MyD88) (1:500, 23230‐I‐AP,

(4) Epigenetic Differences Arise in Endothelial Cells Responding to Cobalt-ChromiumJournal of functional biomaterialsFebruary 26, 2023da C Fernandes CJ, da Silva RAF, de Almeida GS, Ferreira MR, de Morais PB, Bezerra F, Zambuzzi WF.(orb131790) were purchased from BiorByt (San Francisco, CA, USA). Anti-ERK1/ERK2 antibody (ERK-7D8) (ab54230); anti-ERK1/2 (phospho-Thr202/ Tyr204) antibody (ab214362); anti-P38 (ab7952); and anti-P38 (phospho-T180

(5) Yishen Xiezhuo formula ameliorates the development of cisplatin-induced acute kidney injury by attenuating renal tubular epithelial cell senescenceAnnals of translational medicineDecember 1, 2022Zhang Q, Qi J, Luo Q, Wu M, Zhang L, Qin L, Nie X.Affinity Biosciences Cat# AF6319), extracellular regulated protein kinases 1/2 (ERK1/2) (RRID:AB_2139967; Abcam Cat# ab54230), phospho-extracellular regulated protein kinases (p-ERK1/2) (RRID:AB_2139990; Santa Cruz Biotechnology

(6) Inhibition of the immunoproteasome modulates innate immunity to ameliorate muscle pathology of dysferlin-deficient BlAJ miceCell death & diseaseNovember 19, 2022Farini A, Tripodi L, Villa C, Napolitano F, Strati F, Molinaro D, Facciotti F, Cassani B, Torrente Y.Santa Cruz); TLR4 (1:500, sc-293072, Santa Cruz); phosphoP38 (1:500, E-AB-20949, Elabscience); ERK1-2 (1:500, ab54230, Abcam); phosphoERK1-2 (1:500, E-AB-20868, Elabscience); AMPK-1 α (1:500, sc-74461, Santa Cruz); phosphoAMPK-α1/2

(7) Regulatory Effects of Fyn on Trophoblast Cell Behaviors and FunctionBioMed Research InternationalOctober 25, 2022Qian Liu, Jinli Ding, Qingzhen XieCambridge, MA, USA), anti-HLA-G (79769, 1 : 1000, Cell Signaling Technology, Danvers, CO, USA), anti-ERK1/2 (ab54230, 1 : 1000, Abcam), anti-p-ERK1/2 (ab201015, 1 : 1000, Abcam), anti-STAT3 (ab68153, 1 : 1500, Abcam),

(8) Huangqi Guizhi Wuwu Decoction can prevent and treat oxaliplatin-induced neuropathic pain by TNFα/IL-1β/IL-6/MAPK/NF-kB pathwayAging (Albany NY)June 30, 2022Mingzhu Li, Zheng Li, Xiande Ma, Shengbo Jin, Yang Cao, Xuebing Wang, Jian Zhao, Jianbo Wang, Xin Wang, Jian Xudorsal root. Then, the specimens were incubated with a primary antibody against ERK1/2 (1:50; Abcam, ab54230), p38 (1:250; Abcam, ab170099), JNK (1:1000; Abcam, ab208035), C-Fos (1:800, Abcam, ab208942) CREB (1:400;

(9) Exploring the Mechanism of Weikang Keli in Inhibiting Gastric Cancer through the MAPK Signaling Pathway: Based on Network Pharmacology and Experimental VerificationEvidence-Based Complementary and Alternative MedicineMay 2, 2022Xiang Shao, Yuping Liu, Cuihua Jiang, Yue Sun, Qiyang Zhang, Jialin Gu, Jiege Huo, Canhong Huits docking score is higher. 2.6. Reagents Anti-p38 antibody (ab31828), anti-ERK1 + ERK2 antibody (ab54230), anti-PERK antibody (ab65142), β-actin Antibody (E12-051-1), anti-JNK1 + JNK2 + JNK3 antibody (ab179461),

(10) B7‑H3 promotes the epithelial‑mesenchymal transition of NSCLC by targeting SIRT1 through the PI3K/AKT pathwayMolecular Medicine ReportsJanuary 11, 2022Haixiu Liao, Meng Ding, Nannan Zhou, Ying Yang, Liwen ChenN-cadherin (cat. no. ab76011, 1:5,000), vimentin (cat. no. ab92547, 1:1,000), total (t)-ERK1/2 (cat. no. ab54230, 1:1,000), phosphorylated (p)-ERK1/2 (T202+T204; cat. no. ab214362, 1:1,000) and t-STAT-3 (cat. no.

(11) BHF177 Suppresses Diabetic Neuropathic Pain by Blocking PKC/CaMKII/ERK1/2/CREB Signaling Pathway through Activating GABA(B) ReceptorOxidative medicine and cellular longevityJanuary 1, 2022Liu B, Guan F, Zhao J, Niu Y, Jiang H.ab31), CaMKII (Abcam, ab171095), phosphorylation (p)-mitogen-activated protein kinase (ERK1/2) (Abcam, ab54230), p-CREB (Abcam, ab32096), and beta-actin antibody (Abcam, ab8226). Secondary antibody was mouse anti-rabbit

(12) Interfering with pak4 Protein Expression Affects Osteosarcoma Cell Proliferation and MigrationBioMed Research InternationalDecember 30, 2021Yuxin Fu, Lun Fang, Qipu Yin, Qi Wu, Wei Sui, Ying Sun, Xindi Zhao, Yadi Wu, Lu Zhou(1 : 2000; cat.no.GB13305; Servicebio), P21 (1 : 2000; cat.no. ab86696; Abcam.), Erk (1 : 2000; cat.no. ab54230; Abcam.), E-Cadherin (1 : 2000; cat.no.14472; Cell Signaling Technology, Inc.), and N-Cadherin (1 : 2000

(13) Electrospun fibers enhanced the paracrine signaling of mesenchymal stem cells for cartilage regenerationStem Cell Research & TherapyDecember 1, 2021Nurul Dinah Kadir, Zheng Yang, Afizah Hassan, Vinitha Denslin, Eng Hin Leeanti-FAK (phospho Y576 + Y577) antibody (0.182 μg/ml; Abcam; ab76244), mouse anti-ERK1 + ERK2 antibody (1 μg/ml; Abcam; ab54230), mouse anti-FAK antibody (1 μg/ml; Abcam; ab72140), and mouse anti-β-actin antibody (1 μg/ml; Abcam;

(14) Down-regulation of IGHG1 enhances Protoporphyrin IX accumulation and inhibits hemin biosynthesis in colorectal cancer by suppressing the MEK-FECH axisOpen Life SciencesSeptember 6, 2021Guangjian Yang, Gang Li, Xuemei Du, Wenting Zhou, Xiaohong Zou, Yuanfu Liu, Hong Lv, Zhenjiang Linon-fat milk and then probed with anti-IGHG1 (1:2,000; ab108969; Abcam, Cambridge, MA, USA), anti-ERK (ab54230) and anti-p-ERK (1:2,500; ab192591; Abcam), anti-FECH (1:3,000; ab219349; Abcam), and anti-β-actin (1:3,500;

(15) Hydrazinocurcumin Induces Apoptosis of Hepatocellular Carcinoma Cells Through the p38 MAPK PathwayClinical and Translational ScienceSeptember 1, 2021Hongtao He, Kuangyuan Qiao, Chao Wang, Wuhan Yang, Zhuo Xu, Zhilei Zhang, Yuming Jia, Chong Zhang, Li Pengpro‐caspase‐3 (1: 1000, ab32499), and mouse antibody against p38 (1: 1000, ab31828), ERK (1: 1000, ab54230), p53 (1: 1000, ab1101), and β‐actin (1: 1000, ab8226; Table S2 ). All the above‐mentioned antibodies

(16) Anti-Inflammatory Effect Fraction of Bletilla striata and Its Protective Effect on LPS-Induced Acute Lung InjuryMediators of InflammationMarch 13, 2021Chunchun Zhang, Dandan Ning, Jieli Pan, Cheng Chen, Chengxian Gao, Zhishan Ding, Fusheng Jiang, Meiya Li(ab208035, Abcam, USA), anti-JNK1+JNK2+JNK3(phospho T183+T183+T221) (ab124956, Abcam, USA), anti-ERK1+ERK2 (ab54230, Abcam, USA), anti-Erk1(pT202/pY204)+Erk2 (pT185/pY187) (ab50011, Abcam, USA), anti-Lamin A/C antibody

(17) Concentration-Dependent Pro- and Antitumor Activities of Quercetin in Human Melanoma Spheroids: Comparative Analysis of 2D and 3D Cell Culture ModelsMolecules (Basel, Switzerland)January 30, 2021Hundsberger H, Stierschneider A, Sarne V, Ripper D, Schimon J, Weitzenböck HP, Schild D, Jacobi N, Eger A, Atzler J, et al.anti-ERK1 (phospho T202) + ERK2 (phospho T185) antibody (EPR19401) (ab201015, Abcam), anti-ERK1 + ERK2 antibody (ERK-7D8) (ab54230, Abcam), ß-actin antibody (C4) (sc-47778, Santa Cruz), and vinculin antibody (7F9) (sc-73614 HRP, Santa Cruz

(18) CDCA5 promotes the progression of prostate cancer by affecting the ERK signalling pathwayOncology ReportsJanuary 4, 2021Junpeng Ji, Tianyu Shen, Yang Li, Yixi Liu, Zhiqun Shang, Yuanjie Niucaspase-3,"ab32150, Abcam","1:1,000 dilution for western blotting" ,,1:200 dilution for IHC ERK,"ab54230, Abcam,","1:2,000 dilution for western blotting" ,,1:100 dilution for IHC p-ERK,"ab50011, Abcam","1:1,000

(19) An Essential NRP1-Mediated Role for Tagln2 in Gastric Cancer AngiogenesisFrontiers in oncologyJanuary 1, 2021Jin H, Zheng W, Hou J, Peng H, Zhuo H.60322-1-AP, 19677-1-AP and 13371-1-AP), NRP1, Phospho-ERK1/2, Total ERK1/2 (Abcam, Cat#ab25998, ab50011 and ab54230), Phospho-JNK, and Phospho-C-JUN (Cell Signaling Technology, Cat#4668 and 3270), respectively. Targeted

(20) Long noncoding RNA BSN-AS2 induced by E2F1 promotes spinal osteosarcoma progression by targeting miR-654-3p/SYTL2 axisCancer Cell InternationalDecember 1, 2020Xianwei Zhou, Jitian Li, Junyan Teng, Yufeng Liu, Di Zhang, Linyun Liu, Wenming Zhang(ab218527, 1/1000), SYTL2 (ab231133, 1/1000), Akt (ab235958, 1/1000), p-Akt (ab81283, 1/5000), ERK (ab54230, 1/1000), p-ERK (ab201015, 1/1000) and GAPDH (ab8245, 1/1000) from Abcam (Cambridge, USA). Secondary

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Anti-ERK1 + ERK2 antibody [ERK-7D8] from Abcam

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Anti-ERK1 + ERK2 antibody [ERK-7D8] from Abcam

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