Anti-C5b-9 antibody ab55811 from Abcam

Product Specs
ItemAnti-C5b-9 antibody
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab55811
Antibody TypePrimary
IsotypeIgG
ApplicationsImmunocytochemistry/ Immunofluorescence, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Quantity100 UG
HostRabbit
ClonalityPolyclonal
Conjugate/TagUnconjugated
Concentration5 mg/ml
Gene NameC6
ReactivityHuman
TargetC5b-9

Add to Compare List

Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) Cholesterol crystal formation is a unifying pathogenic mechanism in the development of diabetic retinopathyDiabetologiaSeptember 1, 2023Sandra S. Hammer, Tim F. Dorweiler, Delaney McFarland, Yvonne Adu-Agyeiwaah, Natalia Mast, Nicole El-Darzi, Seth D. Fortmann, Sunil Nooti, Devendra K. Agrawal, Irina A. Pikuleva, et al.cell culture studies, HRECs were stained with antibody against membrane attack complex (MAC) C5b-9 (ab55811, Abcam) at a dilution of 1:100 in PBS with 1.5% BSA overnight at 4°C followed by incubation with chicken

(2) Complement and complement regulatory proteins are upregulated in lungs of COVID-19 patientsPathology - Research and PracticeJuly 1, 2023Xiaowen Ge, Zhui Yu, Xinxin Guo, Ling Li, Ling Ye, Maosong Ye, Jingping Yuan, Chouwen Zhu, Weiguo Hu, Yingyong HouC3b/iC3b/C3d (ab136916, Abcam, Cambridge, MA, USA), C3 (ab200999, Abcam, Cambridge, MA, USA), C5b-9 (ab55811, Abcam, Cambridge, MA, USA), CD59 (ab133707, Abcam, Cambridge, MA, USA), CD55 (ab133684, Abcam, Cambridge,

(3) Endothelial-derived complement factor D contributes to endothelial dysfunction in malignant nephrosclerosis via local complement activationHypertension research : official journal of the Japanese Society of HypertensionJuly 1, 2023Wang Z, Zhang Z, Li Y, Zhang Y, Wei M, Li H, Yang S, Zhou Y, Zhou X, Xing G.observed under a fluorescence microscope (Nikon, Tokyo, Japan). Antibodies against C5b-9 (catalog number: ab55811; Abcam, Cambridge, UK), CFD (catalog number: ab213682; Abcam, Cambridge, UK), and CD34 (catalog number:

(4) Single-cell RNA sequencing reveals the fragility of male spermatogenic cells to Zika virus-induced complement activationNature CommunicationsApril 29, 2023Wei Yang, Li-Bo Liu, Feng-Liang Liu, Yan-Hua Wu, Zi-Da Zhen, Dong-Ying Fan, Zi-Yang Sheng, Zheng-Ran Song, Jia-Tong Chang, Yong-Tang Zheng, et al.(1:100, Abcam, ab11861), rat anti-mouse C3 (1:100, Abcam, ab11862), rabbit anti-mouse MAC (1:100, Abcam, ab55811), rabbit anti-mouse CD45 (1:100, Abcam, ab10558), rabbit anti-mouse Granzyme B (GZMB) (1:100, Abcam,

(5) T follicular helper cells contribute to pathophysiology in a model of neuromyelitis optica spectrum disordersJCI InsightFebruary 22, 2023Leung-Wah Yick, Oscar Ka-Fai Ma, Ethel Yin-Ying Chan, Krystal Xiwing Yau, Jason Shing-Cheong Kwan, Koon-Ho Chan1:200; catalog 019-19741, Wako), rabbit anti–terminal complement complex (anti–C5b-9; 1:200; catalog AB55811, Abcam), rat anti–lymphocyte antigen 6 complex locus G6D (anti-Ly6G; 1:400; catalog AB2557, Abcam),

(6) Mice 3D testicular organoid system as a novel tool to study Zika virus pathogenesisVirologica SinicaFebruary 1, 2023Wei Yang, Chen Zhang, Yan-Hua Wu, Li-Bo Liu, Zi-Da Zhen, Dong-Ying Fan, Zheng-Ran Song, Jia-Tong Chang, Pei-Gang Wang, Jing Ananti-mouse C3 (1:100, Abcam, ab11862), rabbit anti-mouse membrane attack complex (MAC) (1:100, Abcam, ab55811) or mouse anti-ZIKV antibody 4G2 (1:500). After washed with PBS, sections were incubated with secondary

(7) The classical pathway triggers pathogenic complement activation in membranous nephropathyNature communicationsJanuary 28, 2023Seifert L, Zahner G, Meyer-Schwesinger C, Hickstein N, Dehde S, Wulf S, Köllner SMS, Lucas R, Kylies D, Froembling S, et al.goat anti-C3, 1:100; Cappel 55500), C4d (rabbit, 1:50; Hycultec HP8033), C5b-9 (rabbit, 1:200; Abcam ab55811), CFB (goat, 1:50; Complement Technology A235), CFH (goat, 1:100; Complement Technology A237), MBL (rabbit,

(8) Deficiency of CFB attenuates renal tubulointerstitial damage by inhibiting ceramide synthesis in diabetic kidney diseaseJCI insightDecember 22, 2022Sun ZJ, Chang DY, Chen M, Zhao MH.(1:300; Abcam catalog ab11878), C5aR (1:2,000; Abcam catalog ab117579), and C5b-9 (1:1,200; Abcam catalog ab55811) were added for overnight incubation at 4°C. Sections were incubated with anti-mouse secondary antibody

(9) Mechanistic target of rapamycin complex 1 orchestrates the interplay between hepatocytes and Kupffer cells to determine the outcome of immune-mediated hepatitisCell death & diseaseDecember 9, 2022Sun X, Ni Y, Lu Q, Liang Y, Gu M, Xue X, Dai C.stained with hematoxylin-and-eosin (HE), periodic acid-Schiff (PAS) or immunolabeled with C5b-9 (cat: ab55811, Abcam). The staining of human samples was using TSA-RM-275 kit (Panovue, China). For cryosections,

(10) Neutrophils predominate the immune signature of cerebral thrombi in COVID-19 stroke patientsActa Neuropathologica CommunicationsDecember 1, 2022Angela Genchi et al.anti-CD3 (clone 2GV6, Ventana, 790–4341), anti-CD20 (clone L26, Ventana,760–2531) and anti-C5b-9 (Abcam, ab55811). All stained slices were digitized using the Aperio® Microscope Digitizer (Leica Biosystems) at a magnification

(11) MASP-2 and MASP-3 inhibitors block complement activation, inflammation, and microvascular stasis in a murine model of vaso-occlusion in sickle cell diseaseTranslational research : the journal of laboratory and clinical medicineNovember 1, 2022Belcher JD, Nguyen J, Chen C, Abdulla F, Conglin R, Ivy ZK, Cummings J, Dudler T, Vercellotti GM.with primary antibodies to C3 activation fragments C3b/iC3b/C3c (Hycult #HM1065), MAC (C5b-9, Abcam #ab55811), and endothelial cell marker VE cadherin (R&D Systems #AF1002). Primary antibodies in tissues were

(12) Therapeutic Intervention with Anti-Complement Component 5 Antibody Does Not Reduce NASH but Does Attenuate Atherosclerosis and MIF Concentrations in Ldlr-/-.Leiden MiceInternational journal of molecular sciencesSeptember 14, 2022Seidel F, Kleemann R, van Duyvenvoorde W, van Trigt N, Keijzer N, van der Kooij S, van Kooten C, Verschuren L, Menke A, Kiliaan AJ, et al.over 45 min at room temperature. The sections were incubated with rabbit anti-mouse C5b-9 antibody (ab55811, 1:1000 in PBS with 1% normal goat serum, Abcam, Cambridge, UK) overnight at 4 °C and washed three times

(13) "Classical Complement Pathway Inhibition in a ""Human-On-A-Chip"" Model of Autoimmune Demyelinating Neuropathies"Advanced therapeuticsJune 1, 2022Rumsey JW, Lorance C, Jackson M, Sasserath T, McAleer CW, Long CJ, Goswami A, Russo MA, Raja SM, Gable KL, et al.anti-S100 (ThermoFisher 710363), 3) mouse anti-C3/C3b (Abcam ab11871), 4) rabbit anti-C5b-9 (Abcam ab55811) and rabbit anti-GM1 IgG (Abcam ab23943). Following three, five-minute washes with PBS, the coverslips

(14) Recruitment of IL ‐1β‐producing intermediate monocytes enhanced by C5a contributes to the development of malignant pleural effusionThoracic CancerMarch 1, 2022Lisha Luo, Shuanglinzi Deng, Wei Tang, Xinyue Hu, Feifei Yin, Huan Ge, Jiale Tang, Zhonghua Liao, Xiaozhao Li, Juntao Fengmouse anti‐human monoclonal antibody C5a (ab11877) and rabbit anti‐human polyclonal antibody SC5b‐9(ab55811), all antibodies were purchased from Abcam) for 18 h at 4°C. According to the manufacturer's instructions,

(15) C-Reactive Protein Protects Against Acetaminophen-Induced Liver Injury by Preventing Complement OveractivationCellular and molecular gastroenterology and hepatologyJanuary 1, 2022Li HY, Tang ZM, Wang Z, Lv JM, Liu XL, Liang YL, Cheng B, Gao N, Ji SR, Wu Y.number: HM1065; lot number: 24277M0518-A; 1:200), or an anti-C5b-9 antibody (Abcam; catalog number: ab55811; lot number: GR3210984-1; 1:1000) at 4°C overnight followed by an FITC-labeled rabbit anti-rat IgG H&L

(16) Complement C5 is not critical for the formation of sub-RPE deposits in Efemp1 mutant miceScientific ReportsDecember 1, 2021Donita L. Garland, Eric A. Pierce, Rosario Fernandez-Godinoincubated with primary antibodies anti C3/C3b/iC3b/C3d/C3dg (AB11862, Abcam), EFEMP1 (SDIX), MAC (C5b-9 AB55811, Abcam), TIMP-3 (AB39184 Abcam), ELN (sc17581, Santa Cruz Biotechnology), and CFH (AB53800, Abcam) overnight

(17) Complement factor B in high glucose-induced podocyte injury and diabetic kidney diseaseJCI insightOctober 8, 2021Lu Q, Hou Q, Cao K, Sun X, Liang Y, Gu M, Xue X, Zhao AZ, Dai C.(catalog ab192577, Abcam), anti-C3d (catalog AF2655, R&D Systems, Bio-Techne), anti-C5b-9 (catalog ab55811, Abcam), anti-C5aR (catalog BS1522, Bioworld), anti–p-STAT1 (Ser727) (catalog 8826S, Cell Signaling Technology

(18) Enhanced eosinophil-mediated inflammation associated with antibody and complement-dependent pneumonic insults in critical COVID-19Cell reportsOctober 5, 2021Kim DM, Kim Y, Seo JW, Lee J, Park U, Ha NY, Koh J, Park H, Lee JW, Ro HJ, et al.AE1/AE3),Agilent,"Cat#M3515, RRID: AB_2132885" Anti-C5b-9 antibody (rabbit polyclonal),Abcam,"Cat#ab55811, RRID:AB_879748" Anti-C3b antibody (mouse monoclonal),Thermo Fisher Scientific,"Cat#MA1-70054, RRID:AB_1073822" Rabbit (DA1E) mAb IgG XP® Isotype Control

(19) Single-cell profiling of infiltrating B cells and tertiary lymphoid structures in the TME of gastric adenocarcinomasOncoImmunologySeptember 13, 2021Lizhou Jia et al.BioLegend), CD8 (SP16, Abcam), CD14 (SP192, Abcam), Foxp3 (D2W8E, CST), C3b (ab11871, Abcam), C5b-9 (ab55811, Abcam) and C5aR1 ((PAB18321, Abnova) on a Leica-Bond III/max autostainer platform (Leica Biosystems).

(20) TPC2 promotes choroidal angiogenesis and inflammation in a mouse model of neovascular age-related macular degenerationLife science allianceAugust 1, 2021Li Y, Schön C, Chen CC, Yang Z, Liegl R, Murenu E, Schworm B, Klugbauer N, Grimm C, Wahl-Schott C, et al.Thermo Fisher Scientific), rabbit anti-Iba-1 (1:500, 019-19741; Wako), or rabbit anti-C5b-9 (1:500, ab55811; Abcam) overnight at 4°C and then incubated with secondary antibodies Alexa Fluor 555 donkey anti-rabbit

Be the First to Write a Review!

Anti-C5b-9 antibody from Abcam

Abcam

Citations (75)

Reviews

Anti-C5b-9 antibody from Abcam

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map