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Anti-MAPK6/ERK3 antibody [EP1720Y]
Anti-MAPK6/ERK3 antibody [EP1720Y] from Abcam
Be the first to write a review!
Citations:
(25)
Supplier Page
Supplier Page from
Abcam for
Anti-MAPK6/ERK3 antibody [EP1720Y]
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Anti-MAPK6/ERK3 antibody [EP1720Y]
Company
Abcam
Price
Supplier Page
View Company Product Page
Catalog Number
ab53277
Antibody Type
Primary
Clonality
Monoclonal
Host
Rabbit
Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Western blot, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Western blot, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Western blot
Quantity
10 UL, 40 UL, 100 UL
Clone
EP1720Y
Isotype
IgG
Conjugate/Tag
Unconjugated
Concentration
2.228 mg/ml
Gene Name
MAPK6
Validation
KnockOut Validated
Reactivity
Human, Mouse, Rat
Target
MAPK6 / ERK-3
Add to Compare List
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB2 0AX
United Kingdom
Phone
: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600
Company Profile
Website:
http://www.abcam.com
Citations (25)
(1)
ERK3/MAPK6 dictates CDC42/RAC1 activity and ARP2/3-dependent actin polymerization
eLife
April 14, 2023
Katarzyna Bogucka-Janczi, Gregory Harms, Marie-May May-Coissieux, Mohamed Bentires-Alj, Bernd Thiede, Krishnaraj Rajalingam
cells were incubated in
1:250
dilution of
anti-ERK3
antibody (
mouse
Cat# MAB3196, R&D or rabbit Cat#
ab53277
,
Abcam
) in blocking solution for 1 hr at RT. For the
ARP3
and CDC42
staining
, the
anti-ARP3
antibody
(2)
Increased methylation of ZNF671 suppresses tumor progression by promoting MAPK6 transcription in laryngeal carcinoma
International journal of biological sciences
January 1, 2023
Zhang W, Liu T, Li X, Li T, Ma X, Zhao D, Zhao X.
follows:
ZNF671
(
Sigma-Aldrich
, Shanghai, China;
HPA046099
,
1:100
), MAPK6 (Abcam, Cambridge, MA, USA;
ab53277
,
1:100
), Ki67 (
Abcam
,
ab15580
,
1:100
), E-cadherin (
Abcam
,
ab76055
,
1:100
), N-cadherin (
Abcam
,
ab76011
,
(3)
On the Therapeutic Potential of ERK4 in Triple-Negative Breast Cancer
Cancers (Basel)
December 21, 2022
Fadia Boudghene-Stambouli, Mathilde Soulez, Natalia Ronkina, Anneke Dörrie, Alexey Kotlyarov, Ole-Morten Seternes, Matthias Gaestel, Sylvain Meloche
obtained from the following suppliers: anti-ERK4 (1/1000; #AP7298b) from Abcepta; anti-ERK3 (1/1000; #
ab53277
) and anti-phospho-
MK5
(Thr182) (1/1000; #
ab138668
) from
Abcam
; anti-HA (1/5000; #
901501
) from
BioLegend
;
(4)
miR-128-3p inhibits the inflammation by targeting MAPK6 in penicillin-induced astrocytes
NeuroReport
December 14, 2022
Yuejiu Pang, Dingzhen Luo, Shuhua Wang
(
ab200478
; RRID:AB_2888939;
1:1,000
;
Abcam
), TNF-α (
ab205587
; RRID:AB_2889389;
1:1,000
;
Abcam
), MAPK6 (
ab53277
; RRID:AB_2140288;
1:1,000
;
Abcam
) and GAPDH (
ab181602
; RRID:AB_2630358;
1:1,000
; Abcam) at 4°C overnight;
(5)
Systematic discovery of mutation-directed neo-protein-protein interactions in cancer
Cell
May 26, 2022
Mo X, Niu Q, Ivanov AA, Tsang YH, Tang C, Shu C, Li Q, Qian K, Wahafu A, Doyle SP,
et al
.
antibody,
Cell signaling
,Cat#
8943
; RRID:AB_11024092 Rabbit monoclonal anti-MAPK6 antibody,
Abcam
,Cat#
ab53277
;RRID:AB_2140288 Rabbit polyclonal anti-
ITPKB
antibody,
Proteintech
,Cat#
12816-1-AP
; RRID:AB_2129846 Rabbit
(6)
Paclitaxel binds and activates C5aR1: A new potential therapeutic target for the prevention of chemotherapy-induced peripheral neuropathy and hypersensitivity reactions
Cell death & disease
May 25, 2022
Brandolini L, d'Angelo M, Novelli R, Castelli V, Giorgio C, Sirico A, Cocchiaro P, D'Egidio F, Benedetti E, Cristiano C,
et al
.
Cell Signaling
), rabbit anti-p-MAPK6/
ERK3
1:1000
(S189,
ab74032
,
Abcam
), rabbit anti-MAPK6/ERK3
1:1000
(
ab53277
,
Abcam
). As secondary antibodies, peroxidase-conjugated anti-rabbit or anti-mouse IgG (
1:30000
; Invitrogen,
(7)
Conditional
ERK3
overexpression cooperates with
PTEN
deletion to promote lung adenocarcinoma formation in mice
Molecular Oncology
March 1, 2022
Sreeram Vallabhaneni, Jian Liu, Marion Morel, Jixin Wang, Francesco J. DeMayo, Weiwen Long
hematoxylin. The primary antibodies used
for immunohistochemistry
are anti‐ERK3 (
1 : 50
dilution,
Abcam
#
ab53277
, Waltham, MA, USA), anti‐TTF1 (
1 : 1000
dilution, DAKO #M3575, Santa Clara, CA, USA), anti‐P63 (
1 : 50
(8)
Rab31 promotes the invasion and metastasis of cervical cancer cells by inhibiting MAPK6 degradation
International journal of biological sciences
January 1, 2022
Huang Y, Liu R, Han X, Hou X, Tian Y, Zhang W.
Sample Kit (
1:1000
;
9782
;
Cell Signaling
), Lamin A/C (
1:1000
;
4777
;
Cell Signaling
), MAPK6 (
1:2000
;
ab53277
;
Abcam
),
MMP2
(
1:1000
;
40994
;
Cell Signaling
), MMP9 (
1:1000
;
13667
;
Cell Signaling
),
p53
(
1:2000
;
10442-1-AP
;
(9)
ERK3 is transcriptionally upregulated by ∆Np63α and mediates the role of ∆Np63α in suppressing cell migration in non-melanoma skin cancers
BMC Cancer
December 1, 2021
Eid S. Alshammari, Amjad A. Aljagthmi, Andrew J. Stacy, Mike Bottomley, H. Nicholas Shamma, Madhavi P. Kadakia, Weiwen Long
antibodies were used
in immunoblotting
:
Mouse
monoclonal anti-pan-p63 (4A4), rabbit monoclonal anti-ERK3 (
ab53277
,
1:1000
,
Abcam
), rabbit polyclonal anti-pRac1 S71 (sc-12924,
1:500
, Santa Cruz),
mouse
monoclonal anti-Rac1(
ab33186
,
(10)
MAPK6-AKT signaling promotes tumor growth and resistance to mTOR kinase blockade
Science Advances
November 12, 2021
Qinbo Cai, Wolong Zhou, Wei Wang, Bingning Dong, Dong Han, Tao Shen, Chad J. Creighton, David D. Moore, Feng Yang
and
MK5
(#
7419
) were from
Cell Signaling Technology
(CST). Other antibodies used include anti-
MAPK6
(#
ab53277
,
Abcam
), anti–β-Actin (#
AC026
,
Abclonal
), anti-FLAG (#
200474
,
Agilent
), and anti-MAPK4 (#AP7298b, Abcepta).
In vitro
(11)
Macrophage polarization-associated lnc-Ma301 interacts with caprin-1 to inhibit hepatocellular carcinoma metastasis through the Akt/Erk1 pathway
Cancer cell international
August 10, 2021
Luo HL, Luo T, Liu JJ, Wu FX, Bai T, Ou C, Chen J, Li LQ, Zhong JH.
(
1:1000
),
Ki67
(
27309-1-AP
,
Proteintech
) (
1:1000
), anti-
AKT1
(
ab179463
,
Abcam
) (
1:1000
), anti-ERK-3 (
ab53277
,
Abcam
) (
1:1000
),
caprin-1
(
ab241071
,
Abcam
) (
1:1000
), and GAPDH (
ab9484
,
Abcam
) (
1:5000
) were used
(12)
Atorvastatin Upregulates microRNA-186 and Inhibits the TLR4-Mediated MAPKs/NF-κB Pathway to Relieve Steroid-Induced Avascular Necrosis of the Femoral Head
Frontiers in Pharmacology
April 16, 2021
Yusong Zhang, Limin Ma, Erhai Lu, Wenhua Huang
ab192890), Beclin-1 (
1:1,000
,
ab210498
), TLR4 (
1:1,000
,
ab95562
), p38MAPK (
1:1,000
,
ab31828
), ERK (
1:1,000
,
ab53277
),
JNK
(
1:1,000
,
ab124956
), NF-κB (
1:1,000
,
ab16502
), and Tubulin (
1:5,000
,
ab7291
) (all from
Abcam
Inc.,
(13)
Down-Regulation of AHNAK2 Inhibits Cell Proliferation, Migration and Invasion Through Inactivating the MAPK Pathway in Lung Adenocarcinoma
Technology in Cancer Research & Treatment
October 1, 2020
Dong-Wei Wang, Hai-Zheng Zheng, Na Cha, Xiao-Jie Zhang, Min Zheng, Ming-Ming Chen, Li-Xiang Tian
AHNAK2 (
ab70053
), Bcl-2 (
ab32124
), Bax (
ab32503
), p-MEK (
ab214445
), MEK (
ab33918
), p-ERK (
ab73209
), ERK (
ab53277
), p-P90RSK (
ab32203
) and P90RSK (
ab32114
), as well as secondary antibody (
1:10,000
;
Abcam
, Cambridge,
(14)
MicroRNA‑490‑3p suppresses the proliferation and invasion of hepatocellular carcinoma cells via targeting TMOD3
Oncology Letters
August 6, 2020
Honghua Wang, Guobao Yang, Yang Yu, Peibing Gu Peibing Gu
no.
ab8805
), anti-p38 (dilution,
1:1,000
; cat. no.
ab31828
), anti-ERK (dilution,
1:1,000
; cat. no.
ab53277
) and anti-β-actin (dilution,
1:1,000
; cat. no.
ab8226
). All the antibodies were purchased from
Abcam
.
(15)
Circular RNA MAPK4 (circ-MAPK4) inhibits cell apoptosis via MAPK signaling pathway by sponging miR-125a-3p in gliomas
Molecular cancer
January 28, 2020
He J, Huang Z, He M, Liao J, Zhang Q, Wang S, Xie L, Ouyang L, Koeffler HP, Yin D,
et al
.
(
ab170099
,
Abcam
),
anti-p38 (phospho T180 + Y182
) antibody (
ab4822
,
Abcam
), anti-MAPK6/ERK-3 [EP1720Y] (
ab53277
,
Abcam
), anti-ERK1 (phospho T202) + ERK2 (phospho T185) [EPR19401] (
ab201015
,
Abcam
), anti-
JNK
(
66210–1-Ig
,
(16)
The atypical MAPK ERK3 potently suppresses melanoma cell growth and invasiveness
Journal of Cellular Physiology
August 1, 2019
Minyi Chen, Amanda K. Myers, Michael P. Markey, Weiwen Long
primary antibodies were used: anti-
BRAF
(
sc-5284
;
Santa Cruz Biotechnology
, Dallas, TX), anti-ERK3 (
ab53277
;
Abcam
, Cambridge, UK), anti-pERK1/2 (
4370
;
Cell Signaling Technology
, Danvers, MA), anti-Rictor (
A300-459A-M
;
(17)
Germ Line Deletion Reveals a Nonessential Role of Atypical Mitogen-Activated Protein Kinase 6/Extracellular Signal-Regulated Kinase 3
Molecular and Cellular Biology
March 15, 2019
N. Ronkina et al.
Hybond ECL
nitrocellulose
membranes
(
GE Healthcare
). Primary antibodies used were anti-ERK3 (EP1720Y;
ab53277
) from
Abcam
,
MK5
(
HPA015515
) from
Atlas
antibody, and GAPDH from Millipore. Secondary
horseradish
peroxidase-conjugated
(18)
L290P/V mutations increase ERK3’s cytoplasmic localization and migration/invasion-promoting capability in cancer cells
Scientific Reports
December 1, 2017
Hadel Alsaran, Lobna Elkhadragy, Astha Shakya, Weiwen Long
previously7,12. The following primary antibodies were used
in Western blotting
: anti-ERK3 (
Abcam
, Cat#
ab53277
), anti-p-ERK3 (S189) (generated for our lab by the monoclonal antibody core facility at Baylor School
(19)
Metformin potentiates the effect of arsenic trioxide suppressing intrahepatic cholangiocarcinoma: roles of p38 MAPK, ERK3, and mTORC1
Journal of Hematology & Oncology
December 1, 2017
Sunbin Ling et al.
MAPK(Thr180/Tyr182, #
4511
), and
Ki-67
(#
9449
) were from
Cell Signaling Technology
, Inc. (Danvers, MA, USA).
ERK3
(
ab53277
) was from
Abcam
(Cambridge, MA, USA). Goat anti-rabbit and goat anti-mouse IgG peroxidase-conjugated
(20)
Long non-coding RNA PTENP1 inhibits proliferation and migration of breast cancer cells via AKT and MAPK signaling pathways
Oncology Letters
October 1, 2017
Sheng Chen, Ye Wang, Jian-Hua Zhang, Qi-Jun Xia, Qiang Sun, Zhen-Kai Li, Jian-Guo Zhang, Mao-Sheng Tang, Mao-Sheng Dong
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Anti-MAPK6/ERK3 antibody [EP1720Y] from Abcam
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