Anti Iba1, Rabbit (for Western Blotting) from FUJIFILM Wako Chemicals U.S.A. Corp

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FUJIFILM Wako Chemicals U.S.A. Corp for
Anti Iba1, Rabbit (for Western Blotting)

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The Anti Iba1, Rabbit (for Western Blotting) Antibody from FUJIFILM Wako Chemicals U.S.A. Corp is a Rabbit Polyclonal antibody. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The Anti Iba1, Rabbit (for Western Blotting) Antibody has been validated for the following applications: Western Blot.

Description

Iba1 (Ionized calcium-binding adapter molecule1) is an approximately 17 kDa calcium-binding protein. It is used as a microglial marker because it is expressed specifically in microglia in the central nervous system. It is expressed in both resting and activated microglia, but is reportedly expressed more highly in activated microglia. It is also expressed in macrophages in peripheral tissues and is known as AIF-1 (Allograft inflammatory factor-1). Iba1 binds to F-actin in cells to form actin bundles. The formation of actin bundles is thought to be required for the membrane ruffling observed during cell migration and phagocytosis. This product is applicapable for Western blotting