Anti-Tuberin antibody [Y320] ab32554 from Abcam

Product Specs
ItemAnti-Tuberin antibody [Y320]
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab32554
Antibody TypePrimary
Quantity10 UL, 40 UL, 100 UL
IsotypeIgG
CloneY320
ClonalityMonoclonal
ApplicationsFlow Cytometry, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Western blot, Flow Cytometry, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Western blot, Flow Cytometry, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Western blot
HostRabbit
Conjugate/TagUnconjugated
Gene NameTSC2
ValidationKnockOut Validated
ReactivityHuman, Mouse, Rat
TargetTuberin

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Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) Relationship between miR‐155 expression and clear cell papillary renal cell carcinoma in the dialyzed kidneyIJU Case ReportsMay 1, 2021Ei Shiomi, Renpei Kato, Tomohiko Matsuura, Shigekatsu Maekawa, Yoichiro Kato, Mitsugu Kanehira, Ryo Takata, Jun Sugimura, Kazuyuki Ishida, Takaya Abe, et al.antibody, sc‐377386, Santa Cruz Biotechnology), TSC2 (phosphorylated antibody: anti‐TSC2 antibody, ab32554, Abcam/nonphosphorylated antibody: Tuberin/TSC2 antibody, #3612, Cell Signaling Technology), mTOR [phosphorylated

(2) Investigation of the novel mTOR inhibitor AZD2014 in neuronal ischemiaNeuroscience LettersJuly 1, 2019Gina Hadley, Daniel J. Beard, Zoi Alexopoulou, Brad A. Sutherland, Alastair M. Buchanantibodies used were:1:1000 rabbit anti- ED hamartin (ab25882, Abcam, UK), 1:1000 rabbit anti-tuberin (ab32554, Abcam, UK), 1:1000 rabbit anti-mTOR (2983 Cell Signaling Technology, USA), 1:1000 rabbit anti-phosmTOR

(3) Feedback Activation of SGK3 and AKT Contributes to Rapamycin Resistance by Reactivating mTORC1/4EBP1 Axis via TSC2 in Breast CancerInternational Journal of Biological SciencesMarch 9, 2019Hongtao Wang et al.addition, γ-Tubulin (sc-7396,1:500) was purchased from Santa Cruz Biotechnology (Santa Cruz, CA). Tuberin (ab32554,1:1000) and INPP4B (ab81269, 1:1000) were purchased from Abcam (Cambridge, UK). Western blot assay Cell

(4) The ciliary protein RPGRIP1L governs autophagy independently of its proteasome-regulating function at the ciliary base in mouse embryonic fibroblastsAutophagyJanuary 1, 2018Struchtrup A, Wiegering A, Stork B, Rüther U, Gerhardt C.(Cell Signaling Technology, 2983), rabbit anti-AKT1 (Cell Signaling Technology, 4691), rabbit anti-TSC2 (Abcam, ab32554), mouse anti-GFP (Roche, 11814460001), rabbit anti-phospho-(Ser33/37/Thr41)-CTNNB1 (Cell Signaling Technology,

(5) Inhibition of ERK1/2 Restores GSK3β Activity and Protein Synthesis Levels in a Model of Tuberous SclerosisScientific reportsJune 23, 2017Pal R, Bondar VV, Adamski CJ, Rodney GG, Sardiello M.Addgene. Anti-GAPDH was purchased from Millipore (MAB374). Anti-TSC2 (for immunoblot) was from Abcam (Ab32554). Anti-puromycin was from Kerafast (EQ0001). LY294002 (9901), siRNA of ERK1/2 (6560), antibodies to

(6) Mesenchymal Tumorigenesis Driven by TSC2 Haploinsufficiency Requires HMGA2 and Is Independent of mTOR Pathway ActivationCancer researchFebruary 15, 2016D'Armiento J, Shiomi T, Marks S, Geraghty P, Sankarasharma D, Chada K.with two additional antibodies (Abcam anti-tuberin (EP1107Y) (ab52936) and Abcam anti-tuberin (Y320) (ab32554)) (a positive tuberin staining for the Y320 antibody is shown in Supplemental Figure S2C). These antibodies

(7) Case report Extracardiac rhabdomyomas – presentation of two cases with analysis of AKT/mTOR and ERK1/2 signalingPolish Journal of PathologyAugust 7, 2015Ewa Iżycka-Świeszewska, Wojciech Wesołowski, Blanka HermannCell Signaling Technology, MA, USA, and antibodies: pERK1/2 (ab 17942, 1 : 200), anti-tuberin [Y320] (ab32554) and anti-hamartin (ab32936) (1 : 100) (Abcam, UK). En Vision technology served for visualization, and

(8) RNA-dependent protein kinase (PKR) depletes nutrients, inducing phosphorylation of AMP-activated kinase in lung cancerOncotargetMay 10, 2015Chengcheng Guo et al.

(9) Autophagy-dependent metabolic reprogramming sensitizes TSC2-deficient cells to the antimetabolite 6-aminonicotinamideMolecular cancer research : MCRJanuary 1, 2014Parkhitko AA, Priolo C, Coloff JL, Yun J, Wu JJ, Mizumura K, Xu W, Malinowska IA, Yu J, Kwiatkowski DJ, et al.

(10) TSC1/2 signaling complex is essential for peripheral naïve CD8+ T cell survival and homeostasis in micePloS oneJanuary 1, 2012Zhang L, Zhang H, Li L, Xiao Y, Rao E, Miao Z, Chen H, Sun L, Li H, Liu G, et al.

(11) A Technical Assessment of the Utility of Reverse Phase Protein Arrays for the Study of the Functional Proteome in Non-microdissected Human Breast CancersClinical proteomicsDecember 1, 2010Hennessy BT, Lu Y, Gonzalez-Angulo AM, Carey MS, Myhre S, Ju Z, Davies MA, Liu W, Coombes K, Meric-Bernstam F, et al.

(12) ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROSProceedings of the National Academy of Sciences of the United States of AmericaMarch 2, 2010Angela Alexander, Sheng-Li Cai, Jinhee Kim, Adrian Nanez, Mustafa Sahin, Kirsteen H MacLean, Ken Inoki, Kun-Liang Guan, Jianjun Shen, Maria D Person, Donna Kusewitt, Gordon B Mills, Michael B Kastan, Cheryl Lyn Walker

(13) Carboxy Terminal Tail of Polycystin-1 Regulates Localization of TSC2 to Repress mTORPLoS ONEFebruary 16, 2010Ruhee Dere, Patricia D. Wilson, Richard N. Sandford, Cheryl Lyn Walker

(14) A Novel Derivative of the Natural Agent Deguelin for Cancer Chemoprevention and TherapyCancer Prevention ResearchJune 30, 2009Woo-Young Kim et al.

(15) The role of the Birt–Hogg–Dubé protein in mTOR activation and renal tumorigenesisOncogeneApril 2, 2009Tiffiney R. Hartman, Emmanuelle Nicolas, Andres Klein-Szanto, Tahseen Al-Saleem, Timothy P. Cash, M. Celeste Simon, Elizabeth P. Henske

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Anti-Tuberin antibody [Y320] from Abcam

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Anti-Tuberin antibody [Y320] from Abcam

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