Fig 1: CYP24A1 expression in PDAC tissue, adjacent non-cancer tissue, and normal pancreas tissue. (A,B) In normal pancreatic tissue, CYP24A1 was zero expressed in exocrine glands and significantly expressed in islets. (C,D) Low expression of CYP24A1 in ANC zone of PDAC. (E,F) High expression of CYP24A1 in ANC zone of PDAC. (G,H) Low expression of CYP24A1 in the C zone of PDAC. (I,J) High expression of CYP24A1 in the C zone of PDAC. Original magnification ×100 (E), ×200 (A, C, G, and I) and ×400 (B, D, F, H, and J). PDAC, pancreatic ductal adenocarcinoma.
Fig 2: Silencing effects of CYP24A1 expression by transfection sequence (n=15). “Si606”, “si1045” and “si1599” are three kinds of small interfering RNA sequences. (A) Change of mRNA levels; (B) change of protein levels; (C) protein bands.
Fig 3: After multivariate analysis with survival, the results prompted that C% (A) and Cin (B) were the independent prognostic factors. The death risk of cases with a high expression of CYP24A1 was lower than those with poor expressions.
Supplier Page from Abcam for Anti-CYP24A1 antibody [EPR9394]