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Anti-Torsin A/DYT1 antibody
Anti-Torsin A/DYT1 antibody from Abcam
Be the first to write a review!
Citations:
(29)
Supplier Page
Supplier Page from
Abcam for
Anti-Torsin A/DYT1 antibody
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Anti-Torsin A/DYT1 antibody
Company
Abcam
Price
Pricing Info
Supplier Page
View Company Product Page
Catalog Number
ab34540
Antibody Type
Primary
Clonality
Polyclonal
Applications
Immunocytochemistry/ Immunofluorescence, Western blot
Isotype
IgG
Host
Rabbit
Quantity
100 UG
Conjugate/Tag
Unconjugated
Concentration
0.5 mg/ml
Gene Name
TOR1A
Reactivity
Human, Mouse, Rat
Target
Torsin A
Add to Compare List
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB2 0AX
United Kingdom
Phone
: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600
Company Profile
Website:
http://www.abcam.com
Citations (29)
(1)
Disulfide bond in SUN2 regulates dynamic remodeling of LINC complexes at the nuclear envelope
Life Science Alliance
August 1, 2023
Rahul Sharma, Martin W Hetzer
MilliporeSigma
); rabbit anti-GFP (#
ab290
-50 μl,
1:1,000
; EnquireBio); rabbit
anti-Torsin A/DYT1
(TOR1A) (#
ab34540
,
1:500
;
Abcam
);
mouse
anti-alpha-Tubulin (aTUB) (#
T5168
,
1:4,000
;
Sigma-Aldrich
). HRP-conjugated secondary
(2)
Alpha-Synuclein is Involved in DYT1 Dystonia Striatal Synaptic Dysfunction
Movement disorders : official journal of the Movement Disorder Society
May 1, 2022
Ponterio G, Faustini G, El Atiallah I, Sciamanna G, Meringolo M, Tassone A, Imbriani P, Cerri S, Martella G, Bonsi P,
et al
.
primary antibodies were used: rabbit (rb) anti‐α‐Syn
1:1000
(D37A6; Cell‐Signaling); rb anti‐TA
1:500
(
ab34540
;
Abcam
);
mouse
(ms) anti‐SNAP‐25
1:8000
(
ab66066
;
Abcam
); rb anti‐SNAP‐23
1:5000
(pab0057‐0; Covalab);
(3)
Vesicular Acetylcholine Transporter Alters Cholinergic Tone and Synaptic Plasticity in DYT1 Dystonia
Movement disorders : official journal of the Movement Disorder Society
December 1, 2021
Tassone A, Martella G, Meringolo M, Vanni V, Sciamanna G, Ponterio G, Imbriani P, Bonsi P, Pisani A.
polyvinylidene fluoride
membranes
were probed with the following primary antibodies: anti‐torsinA (
1:800
,
ab34540
,
Abcam
, Prodotti Gianni, Milan, Italy),
anti‐VGLUT3
(vesicular glutamate transporter 3) (
1:000
,
135203
,
(4)
Characterization of the direct pathway in Dyt1 ΔGAG heterozygous knock-in mice and dopamine receptor 1-expressing-cell-specific Dyt1 conditional knockout mice
Behavioural Brain Research
August 1, 2021
Fumiaki Yokoi, Huan-Xin Chen, Janneth Oleas, Mai Tu Dang, Hong Xing, Kelly M. Dexter, Yuqing Li
and washed with the glycine/PBS for 5 min. The slices were incubated with rabbit anti-torsinA (
Abcam
;
ab34540
;
1:714
dilution) and
goat
anti-Cre (
Santa Cruz
;
sc-83398
;
1:50
dilution) antibodies in 1% BSA/PBS at
(5)
TorsinA restoration in a mouse model identifies a critical therapeutic window for DYT1 dystonia
Journal of Clinical Investigation
March 15, 2021
Jay Li, Daniel S. Levin, Audrey J. Kim, Samuel S. Pappas, William T. Dauer
Supplemental Methods.
Western blotting
PVDF
membranes
were probed with rabbit anti-torsinA (
Abcam
,
ab34540
;
1:10,000
) and rabbit anti-calnexin (Enzo Life Sciences, SPA-860;
1:20,000
) primary antibodies. The
(6)
Effect of Gabapentin in a Neuropathic Pain Model in Mice Overexpressing Human Wild-Type or Human Mutated Torsin A
Life (Basel)
January 12, 2021
Damiana Scuteri, Laura Rombolà, Silvia Natoli, Antonio Pisani, Paola Bonsi, Chizuko Watanabe, Giacinto Bagetta, Paolo Tonin, Maria Tiziana Corasaniti
4 ◦ C with a primary antibody against TA (polyclonal antibody anti-TorsinA produced in rabbit
Abcam
ab34540
), α2δ-1 (monoclonal antibody anti-α2δ-1 produced in
mouse
Sigma
D219
), or the specific neuronal marker
(7)
TorsinB overexpression prevents abnormal twisting in DYT1 dystonia mouse models
eLife
March 23, 2020
Jay Li, Chun-Chi Liang, Samuel S Pappas, William T Dauer
,
Jackson Immunoresearch
,Cat#
705-065-147
RRID:AB_2340397,
IHC
(
1:800
) Antibody,Rabbit polyclonal α-torsinA,
Abcam
,#
ab34540
RRID:AB_2240792,"WB(
1:10,000
)" Antibody,Rabbit polyclonal α-torsinB,Kind gift of Schlieker lab,N/A,"WB(
1:1,000
)" Antibody,"
Goat
(8)
Improved survival and overt “dystonic” symptoms in a torsinA hypofunction mouse model
Behavioural Brain Research
March 1, 2020
Fumiaki Yokoi, Fangfang Jiang, Kelly Dexter, Bryan Salvato, Yuqing Li
torsinA and calnexin levels were detected with a combination of rabbit anti-torsinA antibody (
Abcam
,
ab34540
;
1:1,000
dilution) and IRDye 680RD
donkey anti-rabbit IgG (H+L
) (
LI-COR
,
926–68073
;
1:15
,556 dilution),
(9)
RGS9-2 rescues dopamine D2 receptor levels and signaling in
DYT1
dystonia mouse models
EMBO molecular medicine
January 1, 2019
Bonsi P, Ponterio G, Vanni V, Tassone A, Sciamanna G, Migliarini S, Martella G, Meringolo M, Dehay B, Doudnikoff E,
et al
.
(
1:1,000
,
sc‐8142
;
Santa Cruz
), rabbit anti‐DRD2 (
1:1,000
,
AB5084P
;
Millipore
), rabbit
anti‐torsinA
(
1:800
,
AB34540
;
Abcam
),
goat
anti‐RGS7 (
1:200
,
sc‐8139
;
Santa Cruz
), rabbit
anti‐Gβ5
(
1:1,000
,
071208
;
Millipore
),
(10)
A cell autonomous torsinA requirement for cholinergic neuron survival and motor control
eLife
August 17, 2018
Samuel S Pappas, Jay Li, Tessa M LeWitt, Jeong-Ki Kim, Umrao R Monani, William T Dauer
AB_561049
1:1000
Antibody Iba-1
Wako
019–19741
RRID: AB_839504
1:500
Antibody TorsinA
Abcam
ab34540
RRID: AB_2240792
1:100
Antibody anti-
mouse
ThermoFisher
A-31571
RRID: AB_162542
1:800
Antibody anti-rabbit
ThermoFisher
A-21206
RRID:
(11)
Disruption of Protein Processing in the Endoplasmic Reticulum of DYT1 Knock-in Mice Implicates Novel Pathways in Dystonia Pathogenesis
The Journal of neuroscience : the official journal of the Society for Neuroscience
October 5, 2016
Beauvais G, Bode NM, Watson JL, Wen H, Glenn KA, Kawano H, Harata NC, Ehrlich ME, Gonzalez-Alegre P.
20 – 40 g proteins were separated by
SDS-PAGE
and blotted with the following antibodies: TorsinA (
ab34540
,
Abcam
),
p58
(
2940
,
Cell Signaling Technology
),
BiP
(
3177
,
Cell Signaling Technology
), Kdel (
ADI-SPA-827
,
(12)
Mouse model of rare TOR1A variant found in sporadic focal dystonia impairs domains affected in DYT1 dystonia patients and animal models
Neurobiology of Disease
September 1, 2016
Srishti L. Bhagat, Sunny Qiu, Zachary F. Caffall, Yehong Wan, Yuanji Pan, Ramona M. Rodriguiz, William C. Wetsel, Alexandra Badea, Ute Hochgeschwender, Nicole Calakos
Tris-buffered saline with Tween (TBS-T) + 5% non-fat dry milk and probed with anti-TorsinA antibody (
Abcam
,
ab34540
). To control for gel loading, blots were additionally probed with anti-β-actin (
Chemicon
,
MAB1501
). Human
(13)
Abnormalities of motor function, transcription and cerebellar structure in mouse models of THAP1 dystonia
Human molecular genetics
December 20, 2015
Ruiz M, Perez-Garcia G, Ortiz-Virumbrales M, Méneret A, Morant A, Kottwitz J, Fuchs T, Bonet J, Gonzalez-Alegre P, Hof PR,
et al
.
(14)
A novel conditional knock-in approach defines molecular and circuit effects of the DYT1 dystonia mutation
Human molecular genetics
November 15, 2015
Corinne E Weisheit, William T Dauer
(15)
Forebrain deletion of the dystonia protein torsinA causes dystonic-like movements and loss of striatal cholinergic neurons
eLife
June 8, 2015
Pappas SS, Darr K, Holley SM, Cepeda C, Mabrouk OS, Wong JM, LeWitt TM, Paudel R, Houlden H, Kennedy RT,
et al
.
,Level,Antigen,Host,Conjugated,Dilution,Source
IHC
,Primary,TorsinA,Rabbit,–,
1:100
,
Abcam
ab34540
IHC
,Primary,GFAP,Rabbit,–,
1:2000
,Dako Z0334
IHC
,Primary,s100β,Rabbit,–,
1:2000
,
Abcam
ab41548
IHC
,Primary,Iba-1,Rabbit,–,
1:500
,
Wako
(16)
Dopamine Receptor and Gα(olf) Expression in DYT1 Dystonia Mouse Models during Postnatal Development
PLOS ONE
April 10, 2015
Lin Zhang, Deirdre M. McCarthy, Nutan Sharma, Pradeep G. Bhide
20, the
membranes
were incubated overnight at 4°C with rabbit anti-torsinA antibody (
1:500
;
Abcam
,
ab34540
) in 5% milk TBS-T buffer, rabbit anti-D2R antibody (
1:500
;
Millipore
,
AB5084P
) in 5% BSA TBS-T buffer
(17)
Behavioral and Electrophysiological Characterization of Dyt1 Heterozygous Knockout Mice
PLOS ONE
March 23, 2015
Fumiaki Yokoi, Huan-Xin Chen, Mai Tu Dang, Chad C. Cheetham, Susan L. Campbell, Steven N. Roper, J. David Sweatt, Yuqing Li
torsinA and β-tubulin separately. Each
membrane
was either incubated in the rabbit anti-torsinA (
Abcam
;
ab34540
;
1:1,000
dilution) or HRP-conjugated anti-β-tubulin (
Santa Cruz
;
sc-5274 HRP
;
1:250
dilution) in blocking
(18)
4-Phenylbutyrate Attenuates the ER Stress Response and Cyclic AMP Accumulation in DYT1 Dystonia Cell Models
PLoS ONE
November 7, 2014
Jin A. Cho, Xuan Zhang, Gregory M. Miller, Wayne I. Lencer, Flavia C. Nery
(19)
Dystonia type 6 gene product Thap1: identification of a 50 kDa DNA-binding species in neuronal nuclear fractions
Acta neuropathologica communications
September 18, 2014
Ortiz-Virumbrales M, Ruiz M, Hone E, Dolios G, Wang R, Morant A, Kottwitz J, Ozelius LJ, Gandy S, Ehrlich ME.
dilution. Additionally, monoclonal mouse anti-V5 (Invitrogen) was used at
1:2000
. TorA was detected with
ab34540
rabbit polyclonal (
Abcam
). All primary antibodies were incubated in in PBS-Tween 5% milk for 2 hours
(20)
TorsinA hypofunction causes abnormal twisting movements and sensorimotor circuit neurodegeneration
Journal of Clinical Investigation
July 1, 2014
Chun-Chi Liang, Lauren M. Tanabe, Stephanie Jou, Frank Chi, William T. Dauer
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Anti-Torsin A/DYT1 antibody from Abcam
Supplier Page
View Company Product Page
Pricing Info
Product Specs
Company Info
Citations
Reviews
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