Anti-MEKK2 antibody [EP626Y] ab33918 from Abcam

Product Specs
ItemAnti-MEKK2 antibody [EP626Y]
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab33918
Antibody TypePrimary
IsotypeIgG
CloneEP626Y
Quantity10 UL, 40 UL, 100 UL
ClonalityMonoclonal
ApplicationsFlow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Immunoprecipitation, Western blot, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Immunoprecipitation, Western blot, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Immunoprecipitation, Western blot
HostRabbit
Conjugate/TagUnconjugated
Gene NameMAP3K2
ValidationKnockOut Validated
ReactivityHuman, Mouse, Rat
TargetMEKK2

Add to Compare List

Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) VEGF Stimulates Activation of ERK5 in the Absence of C-Terminal Phosphorylation Preventing Nuclear Localization and Facilitating AKT Activation in Endothelial CellsCellsMarch 22, 2023Anil Kumar Mondru, Mohammad A. Aljasir, Ahmed Alrumayh, Gopika N. Nithianandarajah, Katie Ahmed, Jurgen Muller, Christopher E. P. Goldring, Bettina Wilm, Michael J. Cross(#3007) were purchased from Cell Signalling Technology (Leiden, Netherlands). Antibodies against MEKK2 (#ab33918) and MEKK3 (#ab40750) were purchased from Abcam (Cambridge, UK). All commercial antibodies were used

(2) ZAKβ is activated by cellular compression and mediates contraction‐induced MAP kinase signaling in skeletal muscleThe EMBO JournalSeptember 1, 2022Cathrine Nordgaard et al.phospho‐JNK (T183/Y185, Cell Signaling, 9255, mouse), ZAK (BioSite. 14945‐1‐AP, rabbit), MEKK2 (Abcam, ab33918, rabbit), ERK5 (Cell Signaling, 3372, rabbit), phospho‐AMPK (T172, Cell Signaling, 2535, rabbit), phospho‐ERK1/2

(3) MiR-20a-5p facilitates cartilage repair in osteoarthritis via suppressing mitogen-activated protein kinase kinase kinase 2BioengineeredMay 1, 2022Liu J, Tang G, Liu W, Zhou Y, Fan C, Zhang W.After blocked with 5% nonfat milk, the membranes were incubated with primary antibodies against Map3k2 (ab33918, 1:10000, Abcam), Aggrecan (13880-1-AP, 1:1000, Proteintech, Chicago, USA), collagen II (Col2, ab34712,

(4) MIR205HG acts as a ceRNA to expedite cell proliferation and progression in lung squamous cell carcinoma via targeting miR-299-3p/MAP3K2 axisBMC Pulmonary MedicineDecember 1, 2020Limin Liu, Yulei Li, Ruifang Zhang, Chun Li, Jing Xiong, Yuan Weianti-E-cadherin (ab194982, Abcam), anti-N-cadherin (ab202030, Abcam), anti-Vimentin (ab193555, Abcam), anti-MAP 3 K2 (ab33918, Abcam) and antiGAPDH (ab8245, Abcam). Following washing in TBST, the membranes Liu et al. BMC Pulmonary

(5) Down-Regulation of AHNAK2 Inhibits Cell Proliferation, Migration and Invasion Through Inactivating the MAPK Pathway in Lung AdenocarcinomaTechnology in Cancer Research & TreatmentOctober 1, 2020Dong-Wei Wang, Hai-Zheng Zheng, Na Cha, Xiao-Jie Zhang, Min Zheng, Ming-Ming Chen, Li-Xiang TianUK) overnight at 4°C against AHNAK2 (ab70053), Bcl-2 (ab32124), Bax (ab32503), p-MEK (ab214445), MEK (ab33918), p-ERK (ab73209), ERK (ab53277), p-P90RSK (ab32203) and P90RSK (ab32114), as well as secondary antibody

(6) Hedgehog signaling promotes sorafenib resistance in hepatocellular carcinoma patient-derived organoidsJournal of experimental & clinical cancer research : CRJanuary 28, 2020Wang S, Wang Y, Xun X, Zhang C, Xiang X, Cheng Q, Hu S, Li Z, Zhu J.anti-c-Myc (CST, 5605), anti-Nanog (Abcam, ab109250), anti-Oct4 (Abcam, 181,557), anti-MEKK2 (Abcam, ab33918), anti-MEKK3 (Abcam, ab40756) and anti-GAPDH (Proteintech, 60,004–1-Ig). RNA isolation and quantitative real-time PCR

(7) miR-302a inhibits human HepG2 and SMMC-7721 cells proliferation and promotes apoptosis by targeting MAP3K2 and PBX3Scientific ReportsDecember 1, 2019Meng Wang, Guoyue Lv, Chao Jiang, Shuli Xie, Guangyi Wangincubated with the membranes at 37 °C for 1 h. Then, the membranes were incubated with anti-MAP3K2 (1:500, ab33918, Abcam, USA), anti-PBX3 (1:1000, ab56239, Abcam, USA), anti-p-ERK1/2 (1:1000, ab214362, Abcam, USA),

(8) MEKK2 and MEKK3 suppress Hedgehog pathway-dependent medulloblastoma by inhibiting GLI1 functionOncogeneJuly 1, 2018Lu J, Liu L, Zheng M, Li X, Wu A, Wu Q, Liao C, Zou J, Song H.immunofluorescence. The following antibodies were used: GLI1(C68H3) rabbit mAb (CST, 3538); MEKK2 rabbit mAb (Abcam, ab33918); MEKK3 (Proteintech, 21072-1-AP); Sufu(C81H7) rabbit mAb (CST, 2522); Tubulin rabbit mAb (Abcam, ab6046);

(9) Statin regulated ERK5 stimulates tight junction formation and reduces permeability in human cardiac endothelial cellsJournal of cellular physiologyJanuary 1, 2018Wilkinson EL, Sidaway JE, Cross MJ.and unprenylated RAP1A (SC‐1482) were purchased from Santa Cruz Biotechnology. Antibodies to MEKK2 (ab33918), MEKK3 (ab40750), and MEK5 (ab45146) were purchased from Abcam (Cambridge, UK). Antibody to ZO‐1 (40‐2200)

(10) MicroRNA-186 suppresses cell proliferation and metastasis through targeting MAP3K2 in non-small cell lung cancerInternational Journal of OncologyOctober 1, 2016Tonghai Huang, Kelin She, Guilin Peng, Wei Wang, Jun Huang, Jingpei Li, Zheng Wang, Jianxing Heseparated by 12% SDS-PAGE and detected by western blot analysis using rabbit monoclonal anti-MAP3K2 (ab33918; Abcam, Cambridge, MA, USA) and rabbit monoclonal anti-GAPDH (ab181602; Abcam). Goat anti-rabbit IgG H&L

(11) The transcription factor FOXF1 promotes prostate cancer by stimulating the mitogen-activated protein kinase ERK5Science signalingJanuary 1, 2016Logan Fulford, David Milewski, Vladimir Ustiyan, Navin Ravishankar, Yuqi Cai, Tien Le, Sreeharsha Masineni, Susan Kasper, Bruce Aronow, Vladimir V Kalinichenko, Tanya V Kalin

(12) SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancerNatureJune 12, 2014Mazur PK, Reynoird N, Khatri P, Jansen PW, Wilkinson AW, Liu S, Barbash O, Van Aller GS, Huddleston M, Dhanak D, et al.

(13) MAP kinase kinase kinase-2 (MEKK2) regulates hypertrophic remodeling of the right ventricle in hypoxia-induced pulmonary hypertensionAmerican journal of physiology. Heart and circulatory physiologyJanuary 15, 2013Brown RD, Ambler SK, Li M, Sullivan TM, Henry LN, Crossno JT Jr, Long CS, Garrington TP, Stenmark KR.

(14) Identification of a novel amino acid response pathway triggering ATF2 phosphorylation in mammalsMolecular and cellular biologyDecember 1, 2009Cédric Chaveroux, Céline Jousse, Yoan Cherasse, Anne-Catherine Maurin, Laurent Parry, Valérie Carraro, Benoit Derijard, Alain Bruhat, Pierre Fafournoux

(15) Imaging mass spectrometry of a specific fragment of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase kinase 2 discriminates cancer from uninvolved prostate tissueClinical cancer research : an official journal of the American Association for Cancer ResearchSeptember 1, 2009Lisa H Cazares, Dean Troyer, Savvas Mendrinos, Raymond A Lance, Julius O Nyalwidhe, Hind A Beydoun, Mary Ann Clements, Richard R Drake, O John Semmes

Be the First to Write a Review!

Anti-MEKK2 antibody [EP626Y] from Abcam

Abcam

Citations (15)

Reviews

Anti-MEKK2 antibody [EP626Y] from Abcam

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map