Fig 1: Inducible deletion of Mof by Mx1-Cre.A, an outline of the experimental strategy. B, western blot for MOF and H4K16ac in hepatocytes isolated from polyI:C-treated Moff/f (no Cre recombinase) and Mx1-Cre; Moff/f livers. C, representative immunohistochemistry for MOF protein in livers of the polyI:C treated Moff/f (no Cre recombinase) and Mx1-Cre; Moff/f mice, as indicated on top. Arrows denote cholangiocytes and endothelial cells that escaped Mof deletion. Scale bar, 50 µm. D, representative immunofluorescence images for CK8 and H4K16ac staining in polyI:C-treated adult livers from Moff/f and Mx1-Cre; Moff/f mice following treatment.