Anti-c-Myc antibody [Y69] ab32072 from Abcam

Product Specs
ItemAnti-c-Myc antibody [Y69]
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab32072
Antibody TypePrimary
ClonalityMonoclonal
IsotypeIgG
ApplicationsFlow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Immunoprecipitation, Western blot, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Immunoprecipitation, Western blot, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Immunoprecipitation, Western blot
Quantity10 UL, 40 UL, 100 UL
CloneY69
HostRabbit
Conjugate/TagUnconjugated
Concentration1 mg/ml
Gene NameMYC
ValidationKnockOut Validated
ReactivityHuman, Mouse, Rat
Targetc-Myc

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Abcam

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Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) Exosome-transmitted hsa_circ_0012634 suppresses pancreatic ductal adenocarcinoma progression through regulating miR-147b/HIPK2 axisCancer Biology & TherapyDecember 31, 2023Luoluo Wang, Xiang Wu, Yi Ruan, Xueming Zhang, Xinhua ZhouUSA), anti-GLUT1 (1:2500, ab14683, Abcam), anti-HK2 (1:1000, ab209847, Abcam), anti-c-Myc (1:1000, ab32072, Abcam), anti-HIPK2 (1:1000, 55408–1-AP, Proteintech, Rosemont, IL, USA), anti-CD61 (1:1000, 25682–1-AP,

(2) Asymmetric triplex metallohelices stabilise DNA G-quadruplexes in promoter oncogene sequences and efficiently reduce their expression in cancer cellsJournal of Enzyme Inhibition and Medicinal ChemistryDecember 31, 2023Jaroslav Malina, Hana Kostrhunova, Hualong Song, Peter Scott, Viktor Brabecantibodies: Anti-GAPDH antibody, mouse monoclonal (Sigma-Aldrich; 1:200), Anti-c-Myc antibody [Y69] ab32072 (Abcam; 1:1000), Anti-K-Ras antibody 703 345 (Invitrogen; 1:5000), Goat anti-Mouse IgG (H + L) Secondary

(3) Paeoniflorin suppresses the apoptosis and inflammation of human coronary artery endothelial cells induced by oxidized low-density lipoprotein by regulating the Wnt/β-catenin pathwayPharmaceutical BiologyDecember 31, 2023Shasha Liu, Ying Li, Caojie Wuanti-Bcl2: ab182858 1/2000, anti-GAPDH: ab9485 1/2500, anti-β-catenin: ab32572 1/5000, anti-c-myc: ab32072 1/1000, anti-cyclin D1: ab16663 1/200, anti-E-cadherin: ab40772 1/10,000, Abcam) at 4 °C overnight and

(4) Histone demethylase KDM4B accelerates the progression of glioblastoma via the epigenetic regulation of MYC stabilityClin EpigeneticsDecember 13, 2023Zhongze Wang, Huarui Cai, Zekun Li, Wei Sun, Erhu Zhao, Hongjuan Cui(Guangzhou, China). KDM4B (A301-478A) antibodies from Bethyl, Ki67 (9449) antibodies from CST, and MYC (ab32072) antibodies from Abcam were used for immunohistochemistry (IHC). Cycloheximide (CHX) was obtained from

(5) USP13 drives lung squamous cell carcinoma by switching lung club cell lineage plasticityMol CancerDecember 13, 2023Juntae Kwon, Jinmin Zhang, Boram Mok, Samuel Allsup, Chul Kim, Jeffrey Toretsky, Cecil HanCat# 3728) 1:400, Cytokeratin 5 (Thermo Fisher Scientific, Cat# MA5-17057) 1:2000, MYC (Abcam, Cat# ab32072) 1:400. Images of H&E and IHC-stained slides were acquired on the inverted microscope with microscope

(6) RNA-binding motif protein 10 inactivates c-Myc by partnering with ribosomal proteins uL18 and uL5Proceedings of the National Academy of SciencesDecember 5, 2023Hyemin Lee, Ji Hoon Jung, Hyun Min Ko, Heewon Park, Allyson M. Segall, Roger L. Sheffmaker, Jieqiong Wang, Wesley D. Frey, Nathan Pham, Yongbo Wang, et al.(Santa Cruz, catalogue no. sc-515548, diluted 1:100 for immunofluorescence), anti-c-Myc (Abcam, catalogue no. ab32072, diluted 1:100 for immunohistochemistry), anti-c-Myc (Proteintech, catalogue no. 10828-1-AP, diluted

(7) Upregulation of miR-194-5p or silencing of PRC1 enhances radiotherapy sensitivity in esophageal squamous carcinoma cellsHeliyonDecember 1, 2023Yan Wang, Ninghua Yao, Jie Sunab27798, 1:500), Cyclin D1 (rabbit anti-human ab134175, 1:10000–1:50000), C-myc (rabbit anti-human, ab32072, 1:10000), MMP-2 (rabbit anti-human, ab92536, 1:1000–1:5000), GAPDH (rabbit anti-human, ab9485, 1:2500)

(8) circ-hnRNPU inhibits NONO-mediated c-Myc transactivation and mRNA stabilization essential for glycosylation and cancer progressionJournal of Experimental & Clinical Cancer ResearchNovember 23, 2023Hongjun Li, Wanju Jiao, Jiyu Song, Jianqun Wang, Guo Chen, Dan Li, Xiaojing Wang, Banghe Bao, Xinyi Du, Yang Cheng, et al.previously described [17, 18, 21], with antibodies (1:200 dilutions) specific for NONO (ab70335), c-Myc (ab32072), Flag-tag (ab45766), HA-tag (ab9110), GST-tag (ab36415, Abcam Inc.), or MBP (#2396, Cell Signaling

(9) Micelle-Formulated Juglone Effectively Targets Pancreatic Cancer and Remodels the Tumor MicroenvironmentPharmaceuticsNovember 21, 2023Vidhi M. Shah, Syed Rizvi, Alexander Smith, Motoyuki Tsuda, Madeline Krieger, Carl Pelz, Kevin MacPherson, Jenny Eng, Koei Chin, Michael W. Munks, et al.Biosciences, Lincoln, NE, USA). Primary antibodies’ total MYC (Y69 1:1000, Abcam, Waltham, MA, USA; ab32072), pMYC (1:500, Abcam, Waltham, MA, USA; ab78318), and GAPDH (6C5; 1:5000) were diluted in blocking buffer

(10) Concurrent Targeting of HDAC and PI3K to Overcome Phenotypic Heterogeneity of Castration-resistant and Neuroendocrine Prostate CancersCancer Res CommunNovember 20, 2023Zhang A, Lau NA, Wong A, Brown LG, Coleman IM, De Sarkar N, Li D, DeLucia DC, Labrecque MP, Nguyen HM, et al.Caspase-3 (Asp175) Ab #9661, 1:400; AR (441) Santa Cruz Biotechnology sc-7305, 1:100; c-Myc Ab (Y69) Abcam ab32072, 1:100; ASCL1 antibody BD Biosciences B556604, 1:100] diluted in 2.5% horse serum for 12–18 hours at

(11) Enitociclib, a Selective CDK9 Inhibitor, Induces Complete Regression of MYC+ Lymphoma by Downregulation of RNA Polymerase II Mediated TranscriptionCancer Research CommunicationsNovember 9, 2023Melanie M. Frigault, Arushi Mithal, Harvey Wong, Beatrix Stelte-Ludwig, Vinay Mandava, Xin Huang, Joseph Birkett, Amy J. Johnson, Raquel Izumi, Ahmed HamdySer-2, clone 3E10) rat antibody (Merck, 04-1571-I), recombinant anti-c-MYC rabbit antibody (Y69; Abcam, #ab32072), MCL1 (D5V5L) rabbit antibody (CST, #39224), cleaved-PARP (Asp214) (E2T4K) mouse antibody (CST, #32563),

(12) Long Non-Coding RNA LOC339059 Attenuates IL-6/STAT3-Signaling-Mediated PDL1 Expression and Macrophage M2 Polarization by Interacting with c-Myc in Gastric CancerCancers (Basel)November 7, 2023Haibo Han, Guangyu Ding, Shanshan Wang, Junling Meng, Yunwei Lv, Wei Yang, Hong Zhang, Xianzi Wen, Wei ZhaoUSA, #sc-4772), p-STAT3 (Tyr705; #9145), STAT3 (CST, #12640), IL-6 (Abcam, #ab9324), c-Myc (Abcam, #ab32072), and HRP-conjugated secondary antibodies (Jackson ImmunoResearch). Images were visualized using ECL

(13) CCDC50, an essential driver involved in tumorigenesis, is a potential severity marker of diffuse large B cell lymphomaAnnals of HematologyNovember 1, 2023Yuqi Gong, Hongyan Tong, Fang Yu, Qi Liu, Xianbo Huang, Guoping Ren, Zhongqin Fan, Zhe Wang, Jing Zhao, Zhengrong Mao, et al.buffer (Beyotime, P0013) and subjected to immunoprecipitation using an anti-c-Myc antibody (Abcam, ab32072). The anti-K48-Ub antibody (CST #4289) was used to detect the ubiquitination levels of c-Myc. Exosome

(14) Apoptotic bodies of bone marrow mesenchymal stem cells inhibit endometrial stromal cell fibrosis by mediating the Wnt/β-catenin signaling pathwayHeliyonNovember 1, 2023Zhenghua Xiong, Yaru Ma, Jia He, Qin Li, Liu Liu, Chunli Yang, Jia Chen, Yi Shen, Xuesong Han(1:1000, ab7046), FN (1:5000, ab45688), CTGF (1:1000, ab209780), Wnt2b (1:1000, ab178418), c-MYC (1:1000, ab32072), Cyclin D1 (1:1000, ab16663), CK-18 (1:20000, AB133263), VIM (1:5000, AB92547) and β-catenin (1:10000,

(15) The transcription factor EBF1 non-cell-autonomously regulates cardiac growth and differentiationDevelopmentNovember 1, 2023Eugene E. Kim, Akshay Shekhar, Jayalakshmi Ramachandran, Alireza Khodadadi-Jamayran, Fang-Yu Liu, Jie Zhang, Glenn I. Fishman(MilliporeSigma; 38591150UG, 1:200), Ki-67 (Abcam; AB16667; 1:100), ERG (Abcam; ab92513; 1:100), c-MYC (Abcam; AB32072; 1:100), GFP (Abcam; AB13970; 1:100), WGA (Thermo Fisher Scientific; W112621; 1:500) and visualized

(16) Recombinant immunotoxin induces tumor intrinsic STING signaling against head and neck squamous cell carcinomaScientific ReportsOctober 28, 2023Guiqin Xie, Liang Shan, Cuicui Yang, Yuanyi Liu, Xiaowu Pang, Shaolei Teng, Tzyy-Choou Wu, Xinbin GuIFNB (#27506-1-AP), MX1 (#13750-1-AP) were purchased from Proteintech (Rosemont, IL, USA) and MYC (ab32072), PD-L1 (ab210931) from Abcam (Cambridge, MA, USA). Antibodies against β-actin (#47778 HRP), SOX2 (sc-365823 HRP

(17) FORMATION OF MALIGNANT, METASTATIC SMALL CELL LUNG CANCERS THROUGH OVERPRODUCTION OF cMYC PROTEIN IN TP53 AND RB1 DEPLETED PULMONARY NEUROENDOCRINE CELLS DERIVED FROM HUMAN EMBRYONIC STEM CELLSbioRxivOctober 14, 2023Huanhuan Joyce Chen, Eric E. Gardner, Yajas Shah, Kui Zhang, Abhimanyu Thakur, Chen Zhang, Olivier Elemento, Harold Varmus(R&D systems, cat# AF2408), anti-Ki67 (Cell Signaling, clone D2H10, Cat# 9027, anti-MYC (Abcam, clone Y69, Cat# ab32072), and anti-NEUROD1 (Sigma-Aldrich, clone 3H8, Cat# WH004760M1). All antibodies were used at a 1:150

(18) Targeting of STAT5 using the small molecule topotecan hydrochloride suppresses acute myeloid leukemia progressionOncology ReportsOctober 11, 2023Jiahui Li, Bin Tang, Ying Miao, Guihong Li, Zhenliang Sunphosphorylated (p)-STAT5Y694 (1;500; cat. no. 4322T; Cell Signaling Technology, Inc.), CMYC (1:1,000; cat. no. ab32072; Abcam) and GAPDH (1:1,000; cat. no. ab181602; Abcam) overnight at 4°C. IRDye 680/800 (both 1:10,000;

(19) Signature-driven repurposing of Midostaurin for combination with MEK1/2 and KRASG12C inhibitors in lung cancerNature CommunicationsOctober 10, 2023Irati Macaya, Marta Roman, Connor Welch, Rodrigo Entrialgo-Cadierno, Marina Salmon, Alba Santos, Iker Feliu, Joanna Kovalski, Ines Lopez, Maria Rodriguez-Remirez, et al.30 min at 95 °C in Tris-EDTA, pH 9.0. The following rabbit primary antibodies were used: MYC (Abcam, ab32072) and CD8 (Cell Signalling, 98941). Real time PCR RT-PCR was performed using SYBR® GreenER™Select Master

(20) Class I HDAC inhibition reduces DNA damage repair capacity of MYC-amplified medulloblastoma cellsJournal of Neuro-OncologyOctober 3, 2023Johanna Vollmer, Jonas Ecker, Thomas Hielscher, Gintvile Valinciute, Johannes Ridinger, Nora Jamaladdin, Heike Peterziel, Cornelis M. van Tilburg, Ina Oehme, Olaf Witt, et al.Western blots were performed as previously described [9]. The following antibodies were used: c-MYC (Abcam; ab32072; 1:5000), PARP1 (CellSignalling; #9532S; 1:5000), Rad51 (GeneTex; GTX70230; 1:5000), γH2A.X (CellSignalling;

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12/20/2013Anti c-Myc Monoclonal Antibody (Y69) Rachel CrosslandI am interested in the biology of diffuse large B-cell lymphoma (DLBCL), a high grade aggressive lymphoma. Over-expression of Myc, detected by IHC, has been associated with prognosis in DLBCL and may ... Read Review

Anti-c-Myc antibody [Y69] from Abcam

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Anti-c-Myc antibody [Y69] from Abcam

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