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Antibodies
Antibodies
Anti-CRM1 antibody
Anti-CRM1 antibody from Abcam
Be the first to write a review!
Citations:
(22)
Supplier Page
Supplier Page from
Abcam for
Anti-CRM1 antibody
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Anti-CRM1 antibody
Company
Abcam
Price
Pricing Info
Supplier Page
View Company Product Page
Catalog Number
ab24189
Antibody Type
Primary
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Applications
Immunocytochemistry/ Immunofluorescence, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Western blot
Quantity
100 UG
Conjugate/Tag
Unconjugated
Concentration
0.2 mg/ml
Gene Name
xpo1
Reactivity
Human
Target
CRM1
Add to Compare List
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB2 0AX
United Kingdom
Phone
: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600
Company Profile
Website:
http://www.abcam.com
Citations (22)
(1)
Selective nuclear export inhibitor KPT‑330 enhances the radiosensitivity of esophageal carcinoma cells
Experimental and Therapeutic Medicine
May 16, 2023
Jing Xu, Shan Wu, Guang Li
10 min. The slides were incubated with polyclonal rabbit anti-
human
CRM1 antibody
(
1:180
; cat. no.
ab24189
;
Abcam
) overnight at 4˚C. According to SP kit instructions, the tissues were incubated with biotin-labeled
(2)
Down-regulated expression of CDK5RAP3 and UFM1 suggests a poor prognosis in gastric cancer patients
Frontiers in Oncology
October 27, 2022
Mi Lin, Ning-Zi Lian, Long-Long Cao, Chang-Ming Huang, Chao-Hui Zheng, Ping Li, Jian-Wei Xie, Jia-Bin Wang, Jun Lu, Qi-Yue Chen,
et al.
antigen repaired, blocked and then incubated with appropriate antibodies. The rabbit anti-
human
CDK5RAP3 (
ab24189
;
1:200
;
Abcam
) or
UFM1
(
ab109305
;
1:200
;
Abcam
) antibody was used as the primary antibody.
Immunohistochemical
(3)
RANBP2 and USP9x regulate nuclear import of adenovirus minor coat protein IIIa
PLOS Pathogens
June 16, 2022
Ashrafali M. Ismail, Amrita Saha, Ji S. Lee, David F. Painter, Yinghua Chen, Gurdeep Singh, Gabriela N. Condezo, James Chodosh, Carmen San Martín, Jaya Rajaiya
USP9x
(#ab19879), rabbit polyclonal antibody to
RANBP2
(#ab64276), rabbit polyclonal antibody to CRM1 (#
ab24189
), rabbit polyclonal antibody to
Centromere
-associated protein E (
CENPE
) (#
ab264252
) and
mouse
monoclonal
(4)
The abnormal expression of chromosomal region maintenance 1 (CRM1)-survivin axis in ovarian cancer and its related mechanisms regulating proliferation and apoptosis of ovarian cancer cells
Bioengineered
January 3, 2022
Jing Zhang, Xinyan Xu, Yongfeng Chen, Xiaoju Guan, Hong Zhu, Yuhong Qi
assays
.
Membranes
were blocked with 5% nonfat milk and then incubated with primary antibodies (
anti-CRM1
:
ab24189
;
1:500
, anti-bax:
ab182733
;
1:2000
, anti-
bcl-2
:
ab182858
;
1:2000
,
anti-cleaved Caspase-3
:
ab2302
,
1:500
,
(5)
Selinexor versus doxorubicin in dedifferentiated liposarcoma PDXs: evidence of greater activity and apoptotic response dependent on p53 nuclear accumulation and survivin down‐regulation
Journal of Experimental & Clinical Cancer Research
December 1, 2021
Valentina Zuco et al.
Cell Signaling Technology
), anti-
LC3B
(#
2775
Cell Signaling
), anti-survivin (#
ab469
; Abcam), anti-XPO1 (#
ab24189
;
Abcam
), anti-
LC3B
(#
2775
Cell Signaling Technology), anti-ubiquitin (#
ab7780
,
Abcam
), anti-α-tubulin
(6)
Rational Combination of CRM1 Inhibitor Selinexor and Olaparib Shows Synergy in Ovarian Cancer Cell Lines and Mouse Models
Molecular Cancer Therapeutics
December 1, 2021
Katelyn F. Handley et al.
blocked with 5% milk in TBST for 30 minutes, then incubated with anti-
human
CRM1 antibody
(
1:1000
, Cat.
ab24189
,
Abcam
, RRID: AB_2257217), RAD51 antibody (
1:4000
, Cat.
ABE257
,
Millipore
, RRID: AB_10850319), or
CHEK1
(7)
miR-34a-Mediated Survivin Inhibition Improves the Antitumor Activity of Selinexor in Triple-Negative Breast Cancer
Pharmaceuticals (Basel, Switzerland)
May 29, 2021
Martini S, Zuco V, Tortoreto M, Percio S, Campi E, El Bezawy R, Doldi V, Landesman Y, Pennati M, Zaffaroni N.
SDS-PAGE
, transferred onto nitrocellulose
membranes
and incubated with primary antibodies: anti-XPO1 (
ab24189
;
Abcam
, Cambridge, UK), anti-survivin (
ab469
;
Abcam
), anti-PARP-1 (#
9542
;
Cell Signaling Technology
,
(8)
Crm1 knockdown by specific small interfering RNA reduces cell proliferation and induces apoptosis in head and neck cancer cell lines
TURKISH JOURNAL OF BIOLOGY
March 1, 2019
SİBEL ÖZDAŞ, TALİH ÖZDAŞ
analyses, the
membranes
were incubated at 4 °C overnight with primary antibodies against
Crm1
(1/1000, Cat#
ab24189
;
Abcam
) and β-actin (1/20000, Cat#
sc-47778
;
Santa Cruz Biotechnology, Inc
., Dallas, TX, USA). Then the
(9)
Conserved methionine 165 of matrix protein contributes to the nuclear import and is essential for influenza A virus replication
Virology journal
December 3, 2018
Švančarová P, Betáková T.
(H3N2), matrix protein (I7650-19C) was purchased from US Biological. The rabbit polyclonal
anti-CRM1
antibodies (
ab24189
), anti-NP antibodies (
ab104870
), and
anti-sodium potassium ATPase
antibody(
ab197713
) –
plasma membrane
(10)
The prognostic value of Cyclin-Dependent Kinase 5 and Protein Phosphatase 2A in Gastric Cancer
Journal of Cancer
October 22, 2018
Jian-Xian Lin et al.
Biotechnology Co, Ltd.) for 30 minutes. Next, the sections were incubated with diluted rabbit anti-human CDK5 (
ab24189
diluted
1: 200
.USA) or rabbit anti-
human
PP2Aa (ab32104n diluted
1: 150
;
Abcam
, Cambridge, MA, USA)
(11)
Nuclear entrapment of p33ING1b by inhibition of exportin-1: A trigger of apoptosis in head and neck squamous cell cancer
Cellular and Molecular Biology
April 30, 2018
Sibel í–zdaş
membranes
were incubated at 4° C overnight with primary antibodies against exportin-1 (
1:1000
; Cat#
ab24189
;
Abcam
, Cambridge, MA, USA), p33ING1b (
1:250
; Cat#
sc-7566
-
goat
polyclonal (
Santa Cruz Biotechnology
,
(12)
CRM1/XPO1 expression in pancreatic adenocarcinoma correlates with survivin expression and the proliferative activity
Oncotarget
April 20, 2018
David M. Saulino, Pamela S. Younes, Jennifer M. Bailey, Mamoun Younes
sections were stained by
immunohistochemistry (IHC
) using antibodies to CRM1 (rabbit polyclonal, Cat#
ab24189
,
Abcam
, Inc., www.abcam.com), survivin (rabbit monoclonal antibody, Cat#
2808
,
Clone
71G4B7,
Cell Signaling Technology
(13)
EGFR feedback-inhibition by Ran-binding protein 6 is disrupted in cancer
Nature Communications
December 11, 2017
Barbara Oldrini et al.
1:1000
), EGFR (
ab52894
;
1:960
for
immunofluorescence
staining
), RanGAP1 (
ab92360
;
1:200
), and CRM1 (
ab24189
,
1:1000
) were purchased from
Abcam
. Antibodies to EGFR (#2085;
1:500
for GST-RanBP6 pulldown and
1:1000
–5000
(14)
Expression of CRM1 and CDK5 shows high prognostic accuracy for gastric cancer
World Journal of Gastroenterology
March 21, 2017
Yu-Qin Sun et al.
10%
goat
serum (ZhongShan Biotechnology, China) for 30 min and incubated with rabbit anti-
human
CRM1 (
ab24189
,
1:200
dilution;
Abcam
, Cambridge, MA, United States) or CDK5 (
sc-173
,
1:150
dilution;
Santa Cruz Biotechnology
,
(15)
Nuclear Export Signal Masking Regulates HIV-1 Rev Trafficking and Viral RNA Nuclear Export
Journal of virology
February 1, 2017
Behrens RT, Aligeti M, Pocock GM, Higgins CA, Sherer NM.
to permeabilization using 0.2% Triton X-100 and
incubation
with either rabbit
anti-CRM1
antiserum (
ab24189
;
Abcam
) or
mouse
anti-nucleoporin antiserum (Mab414; Covance) prior to detection using Alexa Fluor 488
(16)
A Nuclear Attack on Traumatic Brain Injury: Sequestration of Cell Death in the Nucleus
CNS Neuroscience & Therapeutics
April 1, 2016
Naoki Tajiri, Ike De La Peña, Sandra A. Acosta, Yuji Kaneko, Sharon Tamir, Yosef Landesman, Robert Carlson, Sharon Shacham, Cesar V. Borlongan
antibody (
1:100
,
ab124341
,
Abcam
, Cambridge, MA, USA), anti‐XPO1 (CRM1) rabbit polyclonal antibody (
1:100
,
ab24189
,
Abcam
), anti‐NF‐kB p65 rabbit polyclonal antibody (
1:100
,
ab16502
,
Abcam
), and anti‐FOXP1 rabbit polyclonal
(17)
The caspase-3-p120-RasGAP module generates a NF-κB repressor in response to cellular stress
Journal of cell science
September 15, 2015
Khalil H, Loukili N, Regamey A, Cuesta-Marban A, Santori E, Huber M, Widmann C.
(18)
Human Exportin-1 is a Target for Combined Therapy of HIV and AIDS Related Lymphoma
EBioMedicine
September 1, 2015
Eline Boons et al.
Santa Cruz Biotechnology
)
caspase-3
(
sc-271028
,
Santa Cruz Biotechnology
),
p53
(
sc-126
, Santa Cruz Biotechnology), XPO1 (
ab24189
,
Abcam
) and α-Tubulin (
sc-5286
,
Santa Cruz Biotechnology
). After washing, the
membranes
were incubated
(19)
Cooperativity among Rev-Associated Nuclear Export Signals Regulates HIV-1 Gene Expression and Is a Determinant of Virus Species Tropism
Journal of Virology
December 15, 2014
Mounavya Aligeti, Ryan T. Behrens, Ginger M. Pocock, Johannes Schindelin, Christian Dietz, Kevin W. Eliceiri, Chad M. Swanson, Michael H. Malim, Paul Ahlquist, Nathan M. Sherer
Triton X-100 and sequential
incubation
with
mouse
anti-Rev antiserum (Rev-6) and rabbit
anti-CRM1
antiserum (
ab24189
;
Abcam
).
Immunoblots
were performed as previously described (52) using
mouse
anti-p24Gag (24-2) (55),
(20)
The myxobacterial metabolite ratjadone A inhibits HIV infection by blocking the Rev/CRM1-mediated nuclear export pathway
Microbial Cell Factories
December 1, 2014
Eric Fleta-Soriano, Javier P Martinez, Bettina Hinkelmann, Klaus Gerth, Peter Washausen, Juana Diez, Ronald Frank, Florenz Sasse, Andreas Meyerhans
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Anti-CRM1 antibody from Abcam
Supplier Page
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