ENaC Alpha antibody orb101489 from Biorbyt | Biocompare.com

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Journal of cellular and molecular medicine
April 01 2020

Fig 1: MCTR1 ameliorates acute lung injury induced by LPS in vitro and in vivo. In this study, we established the acute lung injury model induced by LPS in rats and primary ATII cells. MCTR1 activates ALX, cAMP, PI3K, P-Akt and P-Nedd4-2. In addition, it increases the expression of ENaC and Na, K-ATPase thereby improve the alveolar fluid clearance. ATII, Alveolar Type II; LPS, lipopolysaccharide; MCTR1, Maresin Conjugates in Tissue Regeneration 1

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ENaC Alpha antibody

The ENaC Alpha antibody from Biorbyt is a Rabbit Polyclonal antibody to CDKN2A, SCNN1A, and sodium channel epithelial 1 subunit alpha. This antibody recognizes Homo Sapiens, and Human antigen. The ENaC Alpha antibody has been validated for the following applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.

Description

ENaC Alpha antibody

Product Specs
ItemENaC Alpha antibody
CompanyBiorbyt
Price Pricing Info Supplier Page
Catalog Numberorb101489
Quantity100 µg, 200 µg
ApplicationsICC, IF, IHC-P, WB
Conjugate/TagUnconjugated
Format10 mM PBS, 0.02% sodium azide
ClonalityPolyclonal
TargetENaC Alpha
IsotypeIgG
HostRabbit
PurityPolyclonal antibodies are purified by peptide affinity chromatography
Molecular Weight76 kDa
NCBI Full Gene Namesodium channel, nonvoltage-gated 1 alpha, sodium channel epithelial 1 subunit alpha, cyclin dependent kinase inhibitor 2A
NCBI Gene AliasesSCNEA, mENaC, CDK4I, P19ARF, P16INK4A, CDKN2, ENaCA, MTS-1, P14, P16, P19, P16INK4, MLM, Scnn1, ENaC, MTS1, INK4, TP16, P16-INK4A, CMM2, ARF, P14ARF, INK4A
Concentration- 100 µg (in 200 µl): 0.5 mg/ml- 200 µg (in 400 µl): 0.5 mg/ml
ImmunogenKLH conjugated synthetic peptide derived from human ENaC Alpha. Please contact us for the exact immunogen sequence. The peptide is available as orb12930
StorageStore at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles

Specifications/Features

Application Dilutions: WB: 1:100-800, IHC-P: 1:100-600, IF/ICC: 1:100-600

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Biorbyt

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(1) Maresin Conjugates in Tissue Regeneration 1 improves alveolar fluid clearance by up-regulating alveolar ENaC, Na, K-ATPase in lipopolysaccharide-induced acute lung injuryJournal of cellular and molecular medicineApril 1, 2020Han J, Li H, Bhandari S, Cao F, Wang XY, Tian C, Li XY, Zhang PH, Liu YJ, Wu CH, et al.The ALX inhibitor BOC‐2(RP12950) was purchased from Biomol‐Enzo Life Sciences. The anti‐Na channel α (orb101489), β (orb67568) and γ (orb389322) antibodies were procured from Biorbyt (Cambridge, Cambridge shire)

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